Am J Clin Nutr:孕期补充DHA,后代5岁时都能受益

2016-09-13 Mechront 译 MedSci原创

二十二碳六烯酸(DHA)是大脑的重要组成部分。关于孕期增加DHA摄入的长期效益的证据仍不多。我们对参与产前补充DHA的随机对照试验中的墨西哥妇女和后代进行了研究,评估后代5岁时的认知、行为和注意力情况。 总共有1094名妇女被随机分配接受400毫克/天的DHA或安慰剂,从妊娠18-22周开始,直到分娩。对797名5岁后代(973名活产儿中的82%)进行了认知发展、行为、执行功能和注意力研究(

二十二碳六烯酸(DHA)是大脑的重要组成部分。关于孕期增加DHA摄入的长期效益的证据仍不多。我们对参与产前补充DHA的随机对照试验中的墨西哥妇女和后代进行了研究,评估后代5岁时的认知、行为和注意力情况。

总共有1094名妇女被随机分配接受400毫克/天的DHA或安慰剂,从妊娠18-22周开始,直到分娩。对797名5岁后代(973名活产儿中的82%)进行了认知发展、行为、执行功能和注意力研究(使用麦卡锡儿童能力量表(MSCA)、儿童行为评估系统父母量表第二版(BASC-2)、康纳斯小孩持续性能测试(K-CPT))。

分析结果显示,MSCA分数没有组间差异(P > 0.05),但是DHA组与安慰剂组相比,家庭环境对后代12个月时的认知能力有积极作用(P-相互作用 < 0.05)。BASC-2评分也没有组间差异。对于K-CPT,DHA组与安慰剂组相比,在疏忽方面后代T分有改善(DHA: 47.6 ± 10.3;安慰剂: 49.6 ± 11.2; P < 0.01),在其他K-CPT评分方面,或者对于临床上有注意缺陷多动障碍风险(Bonferroni校正后进行多重比较)的后代中,没有组间差异(P > 0.05)。

结果表明,孕期补充DHA可能有助于改善学龄前儿童的持续性注意力。

原始出处:

Usha Ramakrishnan.et al.Prenatal supplementation with DHA improves attention at 5 y of age: a randomized controlled trial.Am J Clin Nutr.First published September 7, 2016, doi: 10.3945/​

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    2016-09-14 青龙偃月

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    0

  4. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Tue Sep 13 11:58:00 CST 2016, time=2016-09-13, status=1, ipAttribution=)]
    2016-09-14 青龙偃月

    学习了,赞一个!

    0

  5. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Tue Sep 13 11:58:00 CST 2016, time=2016-09-13, status=1, ipAttribution=)]
    2016-09-14 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

  6. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Tue Sep 13 11:58:00 CST 2016, time=2016-09-13, status=1, ipAttribution=)]
    2016-09-14 1dd8a7c5m95(暂无匿称)

    学习了,赞一个!!!

    0

  7. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Tue Sep 13 11:58:00 CST 2016, time=2016-09-13, status=1, ipAttribution=)]
    2016-09-13 医路开来

    二十二碳六烯酸(DHA)是大脑的重要组成部分。

    0

  8. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Tue Sep 13 11:58:00 CST 2016, time=2016-09-13, status=1, ipAttribution=)]
    2016-09-13 医路开来

    孕期补充DHA可能有助于改善学龄前儿童的持续性注意力。

    0

  9. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfdY7yem1P7bRvOP6z0jKsBoYR8ezfAricY7meQWcte7LRJsWHVn0CnPJg2JuQmevR0DoFmmEib5QLD2kNESBESQT/0, createdBy=59191706502, createdName=医路开来, createdTime=Tue Sep 13 11:58:00 CST 2016, time=2016-09-13, status=1, ipAttribution=)]
    2016-09-13 医路开来

    学习啦,,,

    0

  10. 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    2016-09-13 医路开来

    谢谢分享,,

    0

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