ENVIRON RES:这些化妆品或导致不孕

2021-04-07 K.K MedSci原创

使用面膜、口红、面霜、指甲油、染发剂、面霜、发胶、摩丝等产品可能与患子宫内膜异位症增加有关。

近年来,被诊断为宫内膜异位症的妇女人数逐渐增加,子宫内膜异位症是一种常见的妇科疾病:据估计,每10名育龄妇女中就有1名可能患有该病,疾病的特点是子宫内膜组织(位于子宫内侧)异常生长。这种生长将延伸到腹部、骨盆等部位,引发各种症状,常见的症状有骨盆区慢性剧痛、肠道疾病和不孕症,甚至降低了这些妇女的生活质量。从出现症状到确诊则需要10年。子宫内膜异位症也是一种慢性疾病,由于缺乏明确的治疗方法,会给人们日常生活带来极大的挑战。

Granada 大学和San Cecilio de Granada教学医院的研究人员证实:一些化妆品中的确存在内分泌干扰物。研究人员认为使用面膜、口红、指甲油、染发剂、面霜、发胶、摩丝等产品可能与患子宫内膜异位症增加有关。 Granada大学和San Cecilio de Granada教学医院的研究人员将这项研究,发表在近期的《环境研究》杂志上。

 

F.M. Peinado et al. Cosmetic and personal care product use, urinary levels of parabens and benzophenones, and risk of endometriosis: results from the EndEA study, Environmental Research (2020). DOI: 10.1016/j.envres.2020.110342

San Cecilio de Granada教学医院的妇科医生Olga Ocón谈道:"我们怀疑有多种因素参与其中,包括遗传、表观遗传和环境原因,其中激素原因不容忽视。"而内分泌干扰物能够模拟激素对身体造成一些影响。

内分泌干扰物包括对羟基苯甲酸酯和二苯甲酮,这两种物质广泛用于化妆品和美容产品行业。研究人员目前正在研究内分泌干扰物在子宫内膜异位症起着怎样的作用。

科学家们对124名妇女(有或没有子宫内膜异位症)体内对羟基苯甲酸酯和二苯甲酮的含量进行了量化。他们收集了每位妇女使用化妆品和美容产品的详细信息。在年龄、BMI方面,病例组(35例)与对照组(89例)无差异。35例中,卵巢子宫内膜异位症24例(68.6%),子宫内膜异位症深层病变11例(31.4%);子宫内膜异位症I期14例(40.0%)。

子宫内膜异位症病例和对照组的特点

结果显示,频繁地使用一些化妆品(面膜、口红、面霜、足部护理产品、染发剂、面霜、发胶和头发摩丝)与体内较高的对羟基苯甲酸酯和二苯甲酮水平之间存在明显关系。Olga Ocón指出,"一些化妆品里的内分泌干扰物的含量与患子宫内膜异位症的风险有关。"

鉴于子宫内膜异位症难以诊断,目前还没有能够明确治愈子宫内膜异位症的方法,我们也必须采取有效的预防措施,通过使用不含内分泌干扰物的产品,来减少有害物质的接触。

 

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1189727, encodeId=db231189e2796, content=含有这类物质的化妆品还是要少用。, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee616470317, createdName=ms8000002131411968, createdTime=Wed Feb 02 15:49:36 CST 2022, time=2022-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977008, encodeId=08cc9e700818, content=<a href='/topic/show?id=512a20366d0' target=_blank style='color:#2F92EE;'>#不孕症#</a>现在很多很可能与化妆品有关, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20366, encryptionId=512a20366d0, topicName=不孕症)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Sat Jun 26 10:12:47 CST 2021, time=2021-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=955163, encodeId=99db955163c8, content=希望能更进一步公布哪些品牌以便于市民掉坑, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cec72111766, createdName=乙娆, createdTime=Thu Apr 08 11:16:44 CST 2021, time=2021-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346892, encodeId=6a9e1346892a1, content=<a href='/topic/show?id=75e0334e76e' target=_blank style='color:#2F92EE;'>#化妆品#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33477, encryptionId=75e0334e76e, topicName=化妆品)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=796422, createdName=lvliquan, createdTime=Thu Apr 08 07:39:36 CST 2021, time=2021-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1524317, encodeId=224d152431e99, content=<a href='/topic/show?id=053710045ad' target=_blank style='color:#2F92EE;'>#iron#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10045, encryptionId=053710045ad, topicName=iron)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3f1b11597510, createdName=july_979, createdTime=Thu Apr 08 07:39:36 CST 2021, time=2021-04-08, status=1, ipAttribution=)]
    2022-02-02 ms8000002131411968

    含有这类物质的化妆品还是要少用。

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1189727, encodeId=db231189e2796, content=含有这类物质的化妆品还是要少用。, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee616470317, createdName=ms8000002131411968, createdTime=Wed Feb 02 15:49:36 CST 2022, time=2022-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977008, encodeId=08cc9e700818, content=<a href='/topic/show?id=512a20366d0' target=_blank style='color:#2F92EE;'>#不孕症#</a>现在很多很可能与化妆品有关, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20366, encryptionId=512a20366d0, topicName=不孕症)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Sat Jun 26 10:12:47 CST 2021, time=2021-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=955163, encodeId=99db955163c8, content=希望能更进一步公布哪些品牌以便于市民掉坑, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cec72111766, createdName=乙娆, createdTime=Thu Apr 08 11:16:44 CST 2021, time=2021-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346892, encodeId=6a9e1346892a1, content=<a href='/topic/show?id=75e0334e76e' target=_blank style='color:#2F92EE;'>#化妆品#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33477, encryptionId=75e0334e76e, topicName=化妆品)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=796422, createdName=lvliquan, createdTime=Thu Apr 08 07:39:36 CST 2021, time=2021-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1524317, encodeId=224d152431e99, content=<a href='/topic/show?id=053710045ad' target=_blank style='color:#2F92EE;'>#iron#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10045, encryptionId=053710045ad, topicName=iron)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3f1b11597510, createdName=july_979, createdTime=Thu Apr 08 07:39:36 CST 2021, time=2021-04-08, status=1, ipAttribution=)]
    2021-06-26 小小医者

    #不孕症#现在很多很可能与化妆品有关

    0

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    2021-04-08 乙娆

    希望能更进一步公布哪些品牌以便于市民掉坑

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1189727, encodeId=db231189e2796, content=含有这类物质的化妆品还是要少用。, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee616470317, createdName=ms8000002131411968, createdTime=Wed Feb 02 15:49:36 CST 2022, time=2022-02-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=977008, encodeId=08cc9e700818, content=<a href='/topic/show?id=512a20366d0' target=_blank style='color:#2F92EE;'>#不孕症#</a>现在很多很可能与化妆品有关, beContent=null, objectType=article, channel=null, level=null, likeNumber=87, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20366, encryptionId=512a20366d0, topicName=不孕症)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220519/c2ab253484ee4527a2d4e9589a4821ac/45de9bf494a54becb2ea4369c9d11e85.jpg, createdBy=7a3710, createdName=小小医者, createdTime=Sat Jun 26 10:12:47 CST 2021, time=2021-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=955163, encodeId=99db955163c8, content=希望能更进一步公布哪些品牌以便于市民掉坑, beContent=null, objectType=article, channel=null, level=null, likeNumber=97, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cec72111766, createdName=乙娆, createdTime=Thu Apr 08 11:16:44 CST 2021, time=2021-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1346892, encodeId=6a9e1346892a1, content=<a href='/topic/show?id=75e0334e76e' target=_blank style='color:#2F92EE;'>#化妆品#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33477, encryptionId=75e0334e76e, topicName=化妆品)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=796422, createdName=lvliquan, createdTime=Thu Apr 08 07:39:36 CST 2021, time=2021-04-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1524317, encodeId=224d152431e99, content=<a href='/topic/show?id=053710045ad' target=_blank style='color:#2F92EE;'>#iron#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10045, encryptionId=053710045ad, topicName=iron)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3f1b11597510, createdName=july_979, createdTime=Thu Apr 08 07:39:36 CST 2021, time=2021-04-08, status=1, ipAttribution=)]
    2021-04-08 july_979

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