Int J Oral Maxillofac Surg:第三磨牙拔除后辅助性应用富含生长因子的血浆并不会改善术后的疼痛情况

2022-09-20 MedSci原创 MedSci原创

第三磨牙拔除术是口腔科最常见的手术之一,疼痛是患者术后面临的常见困扰。近年来,人们对自体血小板浓缩物(APCs)的再生特性兴趣大增,有大量的证据支持其促进骨和软组织再生的能力。

第三磨牙拔除术是口腔科最常见的手术之一,疼痛是患者术后面临的常见困扰。近年来,人们对自体血小板浓缩物(APCs)的再生特性兴趣大增,有大量的证据支持其通过血小板激活和随后的生长因子释放的生理过程促进骨和软组织再生的能力。近日,发表于Int J Oral Maxillofac Surg的一项研究评估了富含生长因子的血浆(PRGF)对下颌第三磨牙拔除后患者和临床医生报告的结果的影响。

研究共招募了74名需要在局部麻醉下手术拔除单侧下颌第三磨牙的患者。所有患者都准备了PRGF,而不考虑研究组的分配。术后3天(T1)和7天(T2)进行复查。主要结果指标是疼痛(数字评分表,NRS)、OHIP-14(口腔健康影响档案-14)和术后症状严重程度表(PoSSe)数据。此外,研究人员还探讨了次要的结果指标,包括张口度、干牙槽、牙槽愈合和镇痛剂的使用。采用协方差分析和χ2检验进行统计分析。

 

结果显示,PRGF组的NRS疼痛评分在T1时较高,显示出边缘意义(平均差异1.0;P = 0.06),在T2时没有统计学差异。PoSSe评分在各组之间没有显著差异,但T1时"对日常活动的干扰"分量表除外,PRGF组患者的评分高出1.2个单位(P = 0.02)。OHIP-14评分显示,PRGF患者在T1时报告进食不适的可能性增加25%(P = 0.02),在T2时没有统计学意义。次要结果在各组之间均没有显著差异。

综上所述,第三磨牙拔除后,牙槽窝内辅助性应用PRGF并没有改善患者的临床或生活质量,因此,当前的研究并不支持PRGF应用于第三磨牙拔除术。

 

原始出处:

 

L O'Sullivan, et al., Effect of plasma rich in growth factors on quality of life following mandibular third molar removal: a double-blind randomized controlled trial. Int J Oral Maxillofac Surg. 2022 Sep;51(9):1237-1244. doi: 10.1016/j.ijom.2022.02.003.  

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (7)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2020717, encodeId=24792020e17de, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu May 25 17:10:43 CST 2023, time=2023-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956825, encodeId=304a1956825ef, content=<a href='/topic/show?id=7647e210ac' target=_blank style='color:#2F92EE;'>#FAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7210, encryptionId=7647e210ac, topicName=FAC)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Sun Jan 22 03:10:43 CST 2023, time=2023-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2091613, encodeId=d99f209161390, content=<a href='/topic/show?id=f8341466954' target=_blank style='color:#2F92EE;'>#PRF#</a> , beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14669, encryptionId=f8341466954, topicName=PRF)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6edf6489198, createdName=ms3000001190871915, createdTime=Mon Oct 03 17:05:32 CST 2022, time=2022-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2089329, encodeId=f38320893291f, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=71988336493, createdName=ms1000001662327619, createdTime=Tue Sep 20 13:12:34 CST 2022, time=2022-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1518091, encodeId=af4e1518091f9, content=<a href='/topic/show?id=aa2269613cd' target=_blank style='color:#2F92EE;'>#生长因子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69613, encryptionId=aa2269613cd, topicName=生长因子)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3df311117154, createdName=12499e01m50暂无昵称, createdTime=Mon Sep 19 02:10:43 CST 2022, time=2022-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576267, encodeId=e9de15e62674a, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=570716304996, createdName=12498474m35暂无昵称, createdTime=Mon Sep 19 02:10:43 CST 2022, time=2022-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651380, encodeId=942616513801b, content=<a href='/topic/show?id=0e39e5792aa' target=_blank style='color:#2F92EE;'>#第三磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75792, encryptionId=0e39e5792aa, topicName=第三磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c6124182829, createdName=zexyw09, createdTime=Fri Jul 07 05:10:43 CST 2023, time=2023-07-07, status=1, ipAttribution=)]
    2023-05-25 小几洁
  2. [GetPortalCommentsPageByObjectIdResponse(id=2020717, encodeId=24792020e17de, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu May 25 17:10:43 CST 2023, time=2023-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956825, encodeId=304a1956825ef, content=<a href='/topic/show?id=7647e210ac' target=_blank style='color:#2F92EE;'>#FAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7210, encryptionId=7647e210ac, topicName=FAC)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Sun Jan 22 03:10:43 CST 2023, time=2023-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2091613, encodeId=d99f209161390, content=<a href='/topic/show?id=f8341466954' target=_blank style='color:#2F92EE;'>#PRF#</a> , beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14669, encryptionId=f8341466954, topicName=PRF)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6edf6489198, createdName=ms3000001190871915, createdTime=Mon Oct 03 17:05:32 CST 2022, time=2022-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2089329, encodeId=f38320893291f, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=71988336493, createdName=ms1000001662327619, createdTime=Tue Sep 20 13:12:34 CST 2022, time=2022-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1518091, encodeId=af4e1518091f9, content=<a href='/topic/show?id=aa2269613cd' target=_blank style='color:#2F92EE;'>#生长因子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69613, encryptionId=aa2269613cd, topicName=生长因子)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3df311117154, createdName=12499e01m50暂无昵称, createdTime=Mon Sep 19 02:10:43 CST 2022, time=2022-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576267, encodeId=e9de15e62674a, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=570716304996, createdName=12498474m35暂无昵称, createdTime=Mon Sep 19 02:10:43 CST 2022, time=2022-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651380, encodeId=942616513801b, content=<a href='/topic/show?id=0e39e5792aa' target=_blank style='color:#2F92EE;'>#第三磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75792, encryptionId=0e39e5792aa, topicName=第三磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c6124182829, createdName=zexyw09, createdTime=Fri Jul 07 05:10:43 CST 2023, time=2023-07-07, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2020717, encodeId=24792020e17de, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu May 25 17:10:43 CST 2023, time=2023-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956825, encodeId=304a1956825ef, content=<a href='/topic/show?id=7647e210ac' target=_blank style='color:#2F92EE;'>#FAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7210, encryptionId=7647e210ac, topicName=FAC)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Sun Jan 22 03:10:43 CST 2023, time=2023-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2091613, encodeId=d99f209161390, content=<a href='/topic/show?id=f8341466954' target=_blank style='color:#2F92EE;'>#PRF#</a> , beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14669, encryptionId=f8341466954, topicName=PRF)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6edf6489198, createdName=ms3000001190871915, createdTime=Mon Oct 03 17:05:32 CST 2022, time=2022-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2089329, encodeId=f38320893291f, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=71988336493, createdName=ms1000001662327619, createdTime=Tue Sep 20 13:12:34 CST 2022, time=2022-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1518091, encodeId=af4e1518091f9, content=<a href='/topic/show?id=aa2269613cd' target=_blank style='color:#2F92EE;'>#生长因子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69613, encryptionId=aa2269613cd, topicName=生长因子)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3df311117154, createdName=12499e01m50暂无昵称, createdTime=Mon Sep 19 02:10:43 CST 2022, time=2022-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576267, encodeId=e9de15e62674a, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=570716304996, createdName=12498474m35暂无昵称, createdTime=Mon Sep 19 02:10:43 CST 2022, time=2022-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651380, encodeId=942616513801b, content=<a href='/topic/show?id=0e39e5792aa' target=_blank style='color:#2F92EE;'>#第三磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75792, encryptionId=0e39e5792aa, topicName=第三磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c6124182829, createdName=zexyw09, createdTime=Fri Jul 07 05:10:43 CST 2023, time=2023-07-07, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2020717, encodeId=24792020e17de, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu May 25 17:10:43 CST 2023, time=2023-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956825, encodeId=304a1956825ef, content=<a href='/topic/show?id=7647e210ac' target=_blank style='color:#2F92EE;'>#FAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7210, encryptionId=7647e210ac, topicName=FAC)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Sun Jan 22 03:10:43 CST 2023, time=2023-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2091613, encodeId=d99f209161390, content=<a href='/topic/show?id=f8341466954' target=_blank style='color:#2F92EE;'>#PRF#</a> , beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14669, encryptionId=f8341466954, topicName=PRF)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6edf6489198, createdName=ms3000001190871915, createdTime=Mon Oct 03 17:05:32 CST 2022, time=2022-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2089329, encodeId=f38320893291f, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=71988336493, createdName=ms1000001662327619, createdTime=Tue Sep 20 13:12:34 CST 2022, time=2022-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1518091, encodeId=af4e1518091f9, content=<a href='/topic/show?id=aa2269613cd' target=_blank style='color:#2F92EE;'>#生长因子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69613, encryptionId=aa2269613cd, topicName=生长因子)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3df311117154, createdName=12499e01m50暂无昵称, createdTime=Mon Sep 19 02:10:43 CST 2022, time=2022-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576267, encodeId=e9de15e62674a, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=570716304996, createdName=12498474m35暂无昵称, createdTime=Mon Sep 19 02:10:43 CST 2022, time=2022-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651380, encodeId=942616513801b, content=<a href='/topic/show?id=0e39e5792aa' target=_blank style='color:#2F92EE;'>#第三磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75792, encryptionId=0e39e5792aa, topicName=第三磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c6124182829, createdName=zexyw09, createdTime=Fri Jul 07 05:10:43 CST 2023, time=2023-07-07, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=2020717, encodeId=24792020e17de, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu May 25 17:10:43 CST 2023, time=2023-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956825, encodeId=304a1956825ef, content=<a href='/topic/show?id=7647e210ac' target=_blank style='color:#2F92EE;'>#FAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7210, encryptionId=7647e210ac, topicName=FAC)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Sun Jan 22 03:10:43 CST 2023, time=2023-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2091613, encodeId=d99f209161390, content=<a href='/topic/show?id=f8341466954' target=_blank style='color:#2F92EE;'>#PRF#</a> , beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14669, encryptionId=f8341466954, topicName=PRF)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6edf6489198, createdName=ms3000001190871915, createdTime=Mon Oct 03 17:05:32 CST 2022, time=2022-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2089329, encodeId=f38320893291f, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=71988336493, createdName=ms1000001662327619, createdTime=Tue Sep 20 13:12:34 CST 2022, time=2022-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1518091, encodeId=af4e1518091f9, content=<a href='/topic/show?id=aa2269613cd' target=_blank style='color:#2F92EE;'>#生长因子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69613, encryptionId=aa2269613cd, topicName=生长因子)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3df311117154, createdName=12499e01m50暂无昵称, createdTime=Mon Sep 19 02:10:43 CST 2022, time=2022-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576267, encodeId=e9de15e62674a, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=570716304996, createdName=12498474m35暂无昵称, createdTime=Mon Sep 19 02:10:43 CST 2022, time=2022-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651380, encodeId=942616513801b, content=<a href='/topic/show?id=0e39e5792aa' target=_blank style='color:#2F92EE;'>#第三磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75792, encryptionId=0e39e5792aa, topicName=第三磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c6124182829, createdName=zexyw09, createdTime=Fri Jul 07 05:10:43 CST 2023, time=2023-07-07, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=2020717, encodeId=24792020e17de, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu May 25 17:10:43 CST 2023, time=2023-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956825, encodeId=304a1956825ef, content=<a href='/topic/show?id=7647e210ac' target=_blank style='color:#2F92EE;'>#FAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7210, encryptionId=7647e210ac, topicName=FAC)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Sun Jan 22 03:10:43 CST 2023, time=2023-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2091613, encodeId=d99f209161390, content=<a href='/topic/show?id=f8341466954' target=_blank style='color:#2F92EE;'>#PRF#</a> , beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14669, encryptionId=f8341466954, topicName=PRF)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6edf6489198, createdName=ms3000001190871915, createdTime=Mon Oct 03 17:05:32 CST 2022, time=2022-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2089329, encodeId=f38320893291f, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=71988336493, createdName=ms1000001662327619, createdTime=Tue Sep 20 13:12:34 CST 2022, time=2022-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1518091, encodeId=af4e1518091f9, content=<a href='/topic/show?id=aa2269613cd' target=_blank style='color:#2F92EE;'>#生长因子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69613, encryptionId=aa2269613cd, topicName=生长因子)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3df311117154, createdName=12499e01m50暂无昵称, createdTime=Mon Sep 19 02:10:43 CST 2022, time=2022-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576267, encodeId=e9de15e62674a, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=570716304996, createdName=12498474m35暂无昵称, createdTime=Mon Sep 19 02:10:43 CST 2022, time=2022-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651380, encodeId=942616513801b, content=<a href='/topic/show?id=0e39e5792aa' target=_blank style='color:#2F92EE;'>#第三磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75792, encryptionId=0e39e5792aa, topicName=第三磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c6124182829, createdName=zexyw09, createdTime=Fri Jul 07 05:10:43 CST 2023, time=2023-07-07, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=2020717, encodeId=24792020e17de, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu May 25 17:10:43 CST 2023, time=2023-05-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956825, encodeId=304a1956825ef, content=<a href='/topic/show?id=7647e210ac' target=_blank style='color:#2F92EE;'>#FAC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7210, encryptionId=7647e210ac, topicName=FAC)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/B389FA68ECBF51BE2FE14093CF61F6AE/100, createdBy=eb8e2500096, createdName=夏天与十三菇凉, createdTime=Sun Jan 22 03:10:43 CST 2023, time=2023-01-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2091613, encodeId=d99f209161390, content=<a href='/topic/show?id=f8341466954' target=_blank style='color:#2F92EE;'>#PRF#</a> , beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14669, encryptionId=f8341466954, topicName=PRF)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6edf6489198, createdName=ms3000001190871915, createdTime=Mon Oct 03 17:05:32 CST 2022, time=2022-10-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2089329, encodeId=f38320893291f, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=71988336493, createdName=ms1000001662327619, createdTime=Tue Sep 20 13:12:34 CST 2022, time=2022-09-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1518091, encodeId=af4e1518091f9, content=<a href='/topic/show?id=aa2269613cd' target=_blank style='color:#2F92EE;'>#生长因子#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=69613, encryptionId=aa2269613cd, topicName=生长因子)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3df311117154, createdName=12499e01m50暂无昵称, createdTime=Mon Sep 19 02:10:43 CST 2022, time=2022-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1576267, encodeId=e9de15e62674a, content=<a href='/topic/show?id=05a7e3816d7' target=_blank style='color:#2F92EE;'>#磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73816, encryptionId=05a7e3816d7, topicName=磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=570716304996, createdName=12498474m35暂无昵称, createdTime=Mon Sep 19 02:10:43 CST 2022, time=2022-09-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651380, encodeId=942616513801b, content=<a href='/topic/show?id=0e39e5792aa' target=_blank style='color:#2F92EE;'>#第三磨牙#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75792, encryptionId=0e39e5792aa, topicName=第三磨牙)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9c6124182829, createdName=zexyw09, createdTime=Fri Jul 07 05:10:43 CST 2023, time=2023-07-07, status=1, ipAttribution=)]

相关资讯

Rheumatol Ther:托法替布对银屑病关节炎患者疼痛减轻的作用

银屑病关节炎(PSA)影响大约30%的银屑病患者,这项分析旨在利用中介模型量化接受tofacitinib治疗的PSA患者中潜在的炎症相关结果在减轻疼痛方面的作用。

Med Sci Monit:根管治疗后疼痛,试试口服布洛芬

牙髓治疗的目的之一是控制术前和术后疼痛。术后疼痛的原因包括化学介质、与免疫系统有关的因素、心理因素和/或根尖周组织的微生物损伤等。术后疼痛的处理是具有挑战性的,需要使用镇痛剂。

A&R:青少年纤维肌痛期间的脑结构变化与疼痛、疲劳和功能障碍的关系

与疼痛相关的前中扣带回(aMCC)减少可能是青少年FM的结构标志,而涉及情绪、自我参照和语言相关过程的区域的改变可能预测疾病对患者健康的影响。青少年和成人FM之间部分重叠。

Complement Ther Med:烧伤护理过程中,虚拟现实技术可有效减少创口疼痛

烧伤是全世界最常见的伤害之一,具有严重的并发症(如低血容量引起的败血症休克或伤口愈合不当后的疤痕组织收缩),每年在全球造成26.5万人死亡。此外,烧伤的伤口会导致多种疾病,并延长住院和恢复时间。近日,

J Cutan Med Surg:巴瑞克替尼可快速改善快速中重度特应性皮炎患者的皮肤疼痛程度

皮肤疼痛(不适感/疼痛)是特应性皮炎(AD)一种常见的症状。近日,研究人员探究了巴瑞克替尼对皮肤疼痛严重程度的改善效果,以及其对局部治疗反应欠佳的中重度AD患者的生活质量的影响。

J Neuroinflammation:岳阳医院房敏教授团队首次阐释推拿手法镇痛的关键机制

中医推拿解决临床“筋骨病疼痛”问题特色鲜明,疗效显著。我院推拿学科带头人、推拿研究所所长房敏教授团队在前期推拿镇痛研究基础上,首次探索了推拿通过调控外周神经炎性微环境发挥抗炎镇