Lancet:警惕电子烟相关肺损伤!

2019-11-09 不详 MedSci原创

与电子烟有关(也称为E-VALI或VALI)的肺损伤持续爆发,于2019年3月在美国开始。该病的病因、诊断、治疗和病程尚不清楚。研究人员开展一项多中心、前瞻性的观察性队列研究,收集2019年6月27日-10月4日美国Utah所有与电子烟有关的肺损伤患者数据,对此展开研究。共收纳了60位患者。其中33位(55%)住进了重症监护室(ICU)。53位(88%)患者出现体征,59位(8%)患者有呼吸道症状

与电子烟有关(也称为E-VALI或VALI)的肺损伤持续爆发,于2019年3月在美国开始。该病的病因、诊断、治疗和病程尚不清楚。

研究人员开展一项多中心、前瞻性的观察性队列研究,收集2019年6月27日-10月4日美国Utah所有与电子烟有关的肺损伤患者数据,对此展开研究。

共收纳了60位患者。其中33位(55%)住进了重症监护室(ICU)。53位(88%)患者出现体征,59位(8%)患者有呼吸道症状,54位(90%)患者有消化道症状。54位(90%)患者接受抗生素治疗,57位(95%)接受类固醇激素治疗。6位(10%)患者在2周内二次入住ICU或医院,其中3位是因为用电子烟而复发。在2周内随访的26例患者中,虽然所有患者的临床和影像学均有改善,但许多患者的胸片(10/15[67%])和肺功能检查(6/9[67%])仍存在异常。两名患者死亡,与电子烟或电子烟有关的肺损伤被认为是一个诱因,但不是死因。

与电子烟有关的肺损伤是一种新出现的疾病,与严重的肺损伤和体质及肠道症状有关。越来越多的人认识到,在接受抗生素和类固醇治疗的患者中,病情严重程度范围很广。尽管经过治疗患者可获得一定改善,但在短期随访中,大量患者仍有残留异常。与电子烟有关的肺损伤仍然是一种临床诊断,其症状与传染性疾病和其他肺部疾病重叠。保持对这种疾病的高度怀疑仍很重要,对这类患者的病因、最佳治疗和长期预后方面的研究仍需继续。

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    2020-03-11 howi
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    2019-11-11 tastas
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