Crit Care:床旁肺部超声评分对COVID-19患者的预后价值

2020-12-23 MedSci原创 MedSci原创

床旁肺部超声(LUS)已成为一种有用的无创性检查手段,可用于检测COVID-19患者有无肺部受累并监测其变化。但是,LUS评分在COVID-19患者中的临床意义尚未明确。近日,危重病医学领域权威杂志C

床旁肺部超声(LUS)已成为一种有用的无创性检查手段,可用于检测COVID-19患者有无肺部受累并监测其变化。但是,LUS评分在COVID-19患者中的临床意义尚未明确。近日,危重病医学领域权威杂志Critical Care上发表了一篇研究文章,该研究旨在调查LUS评分对COVID-19患者的预后价值。

LUS检查需要对患者12个区域进行扫描,研究人员对280例COVID-19患者进行LUS检查。根据B线、肺实变和胸膜线异常评估了LUS评分。

从入院到LUS检查的中位时间为7天(四分位间距[IQR]为3-10)。相比于最低LUS评分组的患者,LUS评分最高的患者更有可能具有较低的淋巴细胞百分比(LYM%);较高水平的D-二聚体、C反应蛋白、肌钙蛋白I和肌酸激酶肌;更需要机械通气;更高的ARDS发生率;并且死亡率更高。中位随访14天[IQR为10-20天]后,37例患者发展为ARDS,其中13例死亡。相比于无事件幸存者,结果不良的患者双侧肺受累率较高;累及更多的区域和B线,胸膜异常和实变;并且LUS评分更高于。将LUS评分作为连续变量(风险比[HR]:1.05,95%置信区间[CI]1.02〜1.08;P<0.001;Akaike信息标准[AIC]=272;C指标=0.903)或作为分类变量(HR 10.76,95%CI 2.75〜42.05; P = 0.001; AIC = 272; C-index = 0.902)添加到Cox模型相比于基本模型(AIC=286; C指数=0.866)能更准确地预测不良结局。将LUS评分临界值设定为>12预测不良结局的特异性和敏感性分别为90.5%和91.9%。

由此可见,LUS评分在预测COVID-19患者不良结局方面表现良好,对于COVID-19患者的风险分层非常重要

原始出处:

Li Ji.et al.Prognostic value of bedside lung ultrasound score in patients with COVID-19.Critical Care.2020.https://ccforum.biomedcentral.com/articles/10.1186/s13054-020-03416-1

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    2023-05-27 古木5555 来自浙江省

    学习了

    0

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    2020-12-23 ms5000001042177316

    学习了

    0

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    2020-12-23 wxl882001

    了解

    0

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