Clin Nutr:老年营养风险指数(GNRI)与住院时长、炎症标志物显著相关

2016-08-07 Mechront 译 MedSci原创

目的:在老年患者中营养不良是一种普遍的情况,会增加发病率和直接医疗费用;但营养不良的患者很少接受足够的营养评估和治疗。因此,住院患者营养不良的医疗和经济后果往往被低估。本研究的目的是探讨老年营养风险指数(GNRI)能否预测老年患者的住院死亡率、住院时长(LOS)和炎症标志物。方法:我们进行了一项前瞻性单中心研究,纳入500名年龄超过65岁的住院病人(女:248;男:252;年龄:76.3±0.31

目的:在老年患者中营养不良是一种普遍的情况,会增加发病率和直接医疗费用;但营养不良的患者很少接受足够的营养评估和治疗。因此,住院患者营养不良的医疗和经济后果往往被低估。本研究的目的是探讨老年营养风险指数(GNRI)能否预测老年患者的住院死亡率、住院时长(LOS)和炎症标志物。

方法:我们进行了一项前瞻性单中心研究,纳入500名年龄超过65岁的住院病人(女:248;男:252;年龄:76.3±0.31岁)。调整潜在的混杂因素后,评估了GNRI与C-反应蛋白(CRP)、淋巴细胞计数、LOS和全因死亡率之间的关联。

结果:中位数BMI是24.1(第二十五百分位:21.1;第七十五百分位:27.8)kg/m2,平均GNRI 82.2 ± 0.56。更高风险的GNRI与CRP水平的增加有关(p < 0.05),此外还和更低水平的(p < 0.05)有关(p < 0.05)。不仅如此,研究者还发现,更高风险的GNRI与LOS呈正相关,但是与院内死亡率无关。

结论:对于老年患者,GNRI与炎症指标和住院时长密切相关。临床上对老年患者的营养进行常规GNRI评估,或许会对医学和社会经济产生重要影响。

原始出处:

Gärtner S.et al.Geriatric nutritional risk index correlates with length of hospital stay and inflammatory markers in older inpatients.Clin Nutr. 2016 Jul 9. pii: S0261-5614(16)30154-6. doi: 10.1016/j.clnu.2016.06.019.


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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96754, encodeId=b6c196e5426, content=讲的非常好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLF3V7KY7WyRVHCticgpdCWVsqAsLGF1UrrVc5TFS9ZI2DrEs5plCGBUaLqHXvCU4fhImjFdZ9PjiaS/0, createdBy=8f971728670, createdName=1dee1b88m43(暂无匿称), createdTime=Sun Aug 07 16:24:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-09-15 ylzr123

    好文,赞一个,深入学习。

    0

  7. 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19:46:00 CST 2016, time=2016-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105494, encodeId=0fd51054948f, content=赞!文章有深度,值得收藏拜读。, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 12:51:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=97005, encodeId=e1339e0054a, content=营养不良容易致病, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Tue Aug 09 12:02:00 CST 2016, time=2016-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96754, encodeId=b6c196e5426, content=讲的非常好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLF3V7KY7WyRVHCticgpdCWVsqAsLGF1UrrVc5TFS9ZI2DrEs5plCGBUaLqHXvCU4fhImjFdZ9PjiaS/0, createdBy=8f971728670, createdName=1dee1b88m43(暂无匿称), createdTime=Sun Aug 07 16:24:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-09-09 1e10c84am36(暂无匿称)

    赞!好文章,拜读,深入学习。

    0

  8. 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19:46:00 CST 2016, time=2016-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105494, encodeId=0fd51054948f, content=赞!文章有深度,值得收藏拜读。, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 12:51:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=97005, encodeId=e1339e0054a, content=营养不良容易致病, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Tue Aug 09 12:02:00 CST 2016, time=2016-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96754, encodeId=b6c196e5426, content=讲的非常好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLF3V7KY7WyRVHCticgpdCWVsqAsLGF1UrrVc5TFS9ZI2DrEs5plCGBUaLqHXvCU4fhImjFdZ9PjiaS/0, createdBy=8f971728670, createdName=1dee1b88m43(暂无匿称), createdTime=Sun Aug 07 16:24:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-08-27 ylzr123

    赞!文章有深度,值得收藏拜读。

    0

  9. 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status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96754, encodeId=b6c196e5426, content=讲的非常好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLF3V7KY7WyRVHCticgpdCWVsqAsLGF1UrrVc5TFS9ZI2DrEs5plCGBUaLqHXvCU4fhImjFdZ9PjiaS/0, createdBy=8f971728670, createdName=1dee1b88m43(暂无匿称), createdTime=Sun Aug 07 16:24:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-08-09 明崖

    营养不良容易致病

    0

  10. 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encodeId=471312e946f5, content=好文,赞一个,深入学习。, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Thu Sep 15 16:32:00 CST 2016, time=2016-09-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=116816, encodeId=9abf1168168e, content=赞!好文章,拜读,深入学习。, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Fri Sep 09 19:46:00 CST 2016, time=2016-09-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=105494, encodeId=0fd51054948f, content=赞!文章有深度,值得收藏拜读。, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Sat Aug 27 12:51:00 CST 2016, time=2016-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=97005, encodeId=e1339e0054a, content=营养不良容易致病, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=73441710184, createdName=明崖, createdTime=Tue Aug 09 12:02:00 CST 2016, time=2016-08-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96754, encodeId=b6c196e5426, content=讲的非常好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLF3V7KY7WyRVHCticgpdCWVsqAsLGF1UrrVc5TFS9ZI2DrEs5plCGBUaLqHXvCU4fhImjFdZ9PjiaS/0, createdBy=8f971728670, createdName=1dee1b88m43(暂无匿称), createdTime=Sun Aug 07 16:24:00 CST 2016, time=2016-08-07, status=1, ipAttribution=)]
    2016-08-07 1dee1b88m43(暂无匿称)

    讲的非常好!

    0