乳腺癌保乳术后近距离放疗乳房切除术风险加倍

2011-12-07 MedSci原创 MedSci原创

    2011年12月6-10日举行的美国圣安东尼奥乳腺癌大会报告的一项研究显示,接受近距离放疗的女性乳腺癌患者失去乳房的风险较接受全乳放疗者加倍。   美国MD安德森癌症中心放射肿瘤学系助理教授Benjamin D. Smith博士及其同事们评估了2000~2007年诊断的130535例>66岁女性乳腺癌患者的资料。患者接受保乳手术继以部分乳腺加速近距离放疗或

    2011年12月6-10日举行的美国圣安东尼奥乳腺癌大会报告的一项研究显示,接受近距离放疗的女性乳腺癌患者失去乳房的风险较接受全乳放疗者加倍。

  美国MD安德森癌症中心放射肿瘤学系助理教授Benjamin D. Smith博士及其同事们评估了2000~2007年诊断的130535例>66岁女性乳腺癌患者的资料。患者接受保乳手术继以部分乳腺加速近距离放疗或全乳放疗。

  结果显示,接受近距离放疗的患者后续需行乳房切除术的风险为4%,而这一数值在接受全乳放疗的患者中为2.2%。

  Smith说,接受近距离放疗者术后感染和非感染性并发症风险也接近为对照组的两倍。

  “接受近距离放疗的女性发生放疗相关副作用,如乳房疼痛、脂肪坏死和肋骨骨折的概率更高,”他说。

  “我认为该研究结果是可信的,且与先前文献一致,”他说。

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