AJOG:双胎妊娠时的最适孕期体重增加范围

2021-05-14 Nebula MedSci原创

37周时的最适体重增加范围为9.3-16.3kg~

妊娠期孕妇的体重增加是妊娠结局的重要决定因素。单胎妊娠时,妊娠期体重增加过多会增加高血压、糖尿病、早产、剖腹产、巨大儿和儿童期肥胖等并发症的风险。但是,关于双胎妊娠时最佳妊娠期体重增加(GWG)的数据有限。

本研究旨在明确双胎妊娠时GWG的最适范围,同时评估非最适GWG和不良妊娠结局的相关性

这是一项回顾性队列分析研究,纳入了从2000年至2014年有双胎妊娠史的所有女性。研究人员采用两种方法来明确GWG的最适范围:一种统计学方法(正常结局的低危妊娠的GWG的四分位数范围)和一种基于结局的方法(明确不良结局增加的GWG阈值)。主要结局是早产。

共有1274位有双胎妊娠史的女性符合本研究纳入标准,将其划分至体重不足(43位)、正常体重(777位)、超重(278位)和肥胖(176)位

IOM推荐的双胎妊娠孕期体重增加范围

经评估明确,除了肥胖的女性,最适的GWG范围与医学研究所(IOM)推荐的范围相似:本研究得出的37周时的最适GWG范围为9.3-16.3kg,稍低于IOM的推荐值(11.3-19.1kg)

在该研究队列中,接近一半的孕妇的GWG不在推荐范围内:30%(n=381)的个体的体重增加量偏低,17%(n=216)的个体的体重增加量超过了IOM的当前推荐量。

在整个GWG范围内的不良事件风险

对于正常体重组的个体,GWG低于推荐量可增加早产和新生儿低出生体重风险,但同时可降低高血压疾病风险;而GWG高于推荐量可增加高血压疾病风险,降低低出生体重儿风险。该相关性在超重和肥胖组中均不明显。

总之,该研究结果提示孕期体重增加量是双胎妊娠发生早产和其他妊娠并发症的一个可调控的风险因素。

原始出处:

Lipworth Hayley,Melamed Nir,Berger Howard et al. Maternal Weight Gain and Pregnancy Outcomes in Twin Gestations.[J] .Am J Obstet Gynecol, 2021, undefined: undefined.https://doi.org/10.1016/j.ajog.2021.04.260

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    2021-06-10 CCXX88CCXX

    涨知识啦

    0

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    2021-05-14 ms8757542268147266

    学习了

    0

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