JACC:先心病孕妇分娩时的不良事件风险明显更高

2019-05-08 Nathan MedSci原创

患有先心病的孕妇在分娩时发生不良事件的风险会更高,本研究的目的旨在评估和比较患有先心病孕妇和不患有先心病孕妇分娩时发生的不良心血管、产科和胎儿结局。本研究纳入了美国2008-2013年期间22881691名孕妇,其中17729名患有先心病(77.5/100000),与非先心病孕妇相比,先心病孕妇的住院时间和费用更高,并发症的发病率也更高,包括肺动脉高压(aOR: 193.8; 95% [CI]:

患有先心病的孕妇在分娩时发生不良事件的风险会更高,本研究的目的旨在评估和比较患有先心病孕妇和不患有先心病孕妇分娩时发生的不良血管、产科和胎儿结局。

本研究纳入了美国2008-2013年期间22881691名孕妇,其中17729名患有先心病(77.5/100000),与非先心病孕妇相比,先心病孕妇的住院时间和费用更高,并发症的发病率也更高,包括肺动脉高压(aOR: 193.8; 95% [CI]: 157.7-238.0)、充血性心衰(aOR: 49.1; 95% CI: 37.4-64.3)和冠心病(aOR: 31.7; 95% CI: 21.4-47.0),不良事件的发生风险也更高,包括心衰(aOR: 22.6; 95% CI: 20.5-37.3)、心律失常(aOR: 12.4; 95% CI: 11.0-14.0)、血栓栓塞事件(aOR: 2.4; 95% CI: 2.0-2.9)、先兆子痫(aOR: 1.5; 95% CI: 1.3-1.7)和前置胎盘(aOR: 1.5; 95% CI: 1.2-1.8),剖宫产、引产和手术阴道分娩更常见,而胎儿窘迫则不常见。另外,先心病严重程度对大部分不良事件的影响无明显差异。

研究结果显示,先心病孕妇在分娩时的并发症和不良事件发生风险明显更高。

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    2019-11-07 hbwxf
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    2019-05-10 linlin2312
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    2019-05-10 ssnine
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