抗体药物偶联物治疗肺癌:U3-1402和DS-1062的临床结果更新将在2019年世界肺癌大会上发表

2019-08-22 Allan MedSci原创

Daiichi Sankyo(第一三共株式会社)近日宣布,以评估抗体药物偶联物(ADC)U3-1402和DS-1062治疗晚期或转移性非小细胞肺癌(NSCLC)的最新数据将于2019年9月7日至10日在世界肺癌大会上发表。

Daiichi Sankyo(第一三共株式会社)近日宣布,以评估抗体药物偶联物(ADCU3-1402DS-1062治疗晚期或转移性非小细胞肺癌NSCLC)的最新数据将于201997日至10日在世界肺癌大会上发表。U3-1402是一种潜在的HER3靶向ADC,用于EGFR突变的转移性NSCLC患者,该类患者已对TKI治疗产生抗药性;DS-1062是一种潜在的TROP2靶向ADC,用于晚期NSCLC患者。

抗体药物偶联物(antibody-drug conjugateADC)是通过一个化学链接将具有生物活性的小分子药物连接到单克隆抗体上,而单克隆抗体作为载体将小分子药物靶向运输到目标细胞中。


原始出处:

http://www.firstwordpharma.com/node/1660980#axzz5xBxiqv3r

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