Dent Mater J:比较不同生物材料促进垂直性骨缺损愈合的能力

2019-12-08 lishiting MedSci原创

由严重牙周炎引起的垂直性骨吸收的治疗需要牙周组织的再生。尽管多种骨置换物已经应用于临床治疗垂直性骨缺损,但是这些材料在牙周组织中的评价还不完善。这篇研究的目的是为了检测多种骨置换物在3壁骨缺损的动物模型中的骨再生能力,包括:半胱氨酸、陶瓷吸附剂、新骨和Bio-Oss。

由严重牙周炎引起的垂直性骨吸收的治疗需要牙周组织的再生。尽管多种骨置换物已经应用于临床治疗垂直性骨缺损,但是这些材料在牙周组织中的评价还不完善。这篇研究的目的是为了检测多种骨置换物在3壁骨缺损的动物模型中的骨再生能力,包括:半胱氨酸、陶瓷吸附剂、新骨和Bio-Oss。结果显示,所有这些骨置换物对牙周膜和牙骨质的愈合均表现出相似的效果。然而,在植入后4周,半胱氨酸与其他材料相比促进骨愈合能力更快。另外,4周的半胱氨酸移植瓣中可检测到破骨细胞和内皮细胞的募集,但在其他材料中仅在8周时才可检测到。这些结果表明,半胱氨酸能够通过诱导骨重建和血管再生促进骨快速愈合。原始出处:Sato N, Handa K. Comparison of the vertical bone defect healing abilities of carbonate apatite, β-tricalcium phosphate, hydroxyapatite and bovine-derived heterogeneous bone. Dent Mater J. 2019 Nov 28. doi: 10.4012/

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    2019-12-10 lfcmxl
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