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NantKwest的NK细胞疗法联合T细胞激活剂在转移性胰腺癌患者的早期临床试验中，将肿瘤根除

2020-01-17 不详 MedSci原创

NantKwestNK细胞疗法T细胞激活剂转移性胰腺癌肿瘤根除
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总部位于加利福尼亚的生物技术公司NantKwest（NK）透露，其实验性癌症药物在首批接受治疗的胰腺癌患者中展现出有潜力的结果。早期结果来自转移性胰腺癌患者，该患者接受了NK的"自然杀伤细胞（NK细胞）"治疗，并与ImmunityBio公司的IL-15融合蛋白结合使用。

总部位于加利福尼亚的生物技术公司NantKwest（NK）透露，其实验性癌症药物在首批接受治疗的胰腺癌患者中展现出有潜力的结果。早期结果来自转移性胰腺癌患者，该患者接受了NK的"自然杀伤细胞（NK细胞）"治疗，并与ImmunityBio公司的IL-15融合蛋白结合使用。

NK在一份声明中说，这种特殊的组合可以诱导"自然杀伤细胞"和T细胞的免疫系统激活，从而导致二线转移性癌症患者的完全反应，这一点已得到PET / CT结果的证实。

胰腺癌的特征是难以击败，并且存活率很低，诊断后五年内只有不到7％的患者还活着。众所周知，它也很难靶向，因此严重缺乏新的治疗选择。

该公司首席执行官Patrick Soon-Shiong告诉Bloomberg Television，该患者的肿瘤在通过实验疗法治疗后得以根除。

根据Soon-Shiong的说法，前十个患者在试验中具有部分响应，没有能够完全根除肿瘤，此次强烈的变化结果是在第11名患者中观察到的。明显的不同之处在于，这名最新患者接受了PD-L1单抗的治疗。

这项惊人的结果建立在NK最近在三阴性乳腺癌患者中报告的数据的基础上，他们也接受了类似的联合疗法，并获得了完全的反应。

消息传出后，该公司股价飙升91％，至6.80美元，这是自2015年该股票开始交易以来的最大涨幅。

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    2020-11-19 风铃830

    #根除#

    0

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    2020-03-21 若水123

    #T细胞激活剂#

    0

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    2020-10-21 xiangyuzhou971

    #EST#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1683698, encodeId=2aca16836985d, content=<a href='/topic/show?id=c2fc6228167' target=_blank style='color:#2F92EE;'>#根除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62281, encryptionId=c2fc6228167, topicName=根除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=07d627990740, createdName=风铃830, createdTime=Thu Nov 19 18:24:00 CST 2020, time=2020-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1796510, encodeId=85831e965106b, content=<a href='/topic/show?id=ec8f18029a2' target=_blank style='color:#2F92EE;'>#T细胞激活剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18029, encryptionId=ec8f18029a2, topicName=T细胞激活剂)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIOca9icPByKxo3ZRUrvuibf7tWt7EScQ1NEiaKy4NCUctSU2jDjOayLicDIaicwUxaQhJ1SZKdEevgjRg/132, createdBy=4f272500131, createdName=若水123, createdTime=Sat Mar 21 20:24:00 CST 2020, time=2020-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051493, encodeId=caef20514930b, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Wed Oct 21 11:24:00 CST 2020, time=2020-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1809201, encodeId=874e180920133, content=<a href='/topic/show?id=2f1a829e75c' target=_blank style='color:#2F92EE;'>#肿瘤根除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82977, encryptionId=2f1a829e75c, topicName=肿瘤根除)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erCiat0j36p5MejdM9yCLtcVcY8WS5VIKuCMqXFNs56U6iacZib5CJvh6mVxGERicM6ZAkl91jMgpcDrw/132, createdBy=37622500012, createdName=ms2999106592497887, createdTime=Sun Feb 09 19:24:00 CST 2020, time=2020-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2086595, encodeId=4c2d208659594, content=<a href='/topic/show?id=c1bd1251583' target=_blank style='color:#2F92EE;'>#NantKwest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12515, encryptionId=c1bd1251583, topicName=NantKwest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e72268, createdName=zhixianchen, createdTime=Mon Mar 09 16:24:00 CST 2020, time=2020-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1386580, encodeId=3203138658002, content=<a href='/topic/show?id=f08293399f9' target=_blank style='color:#2F92EE;'>#转移性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93399, encryptionId=f08293399f9, topicName=转移性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1390226, encodeId=14a913902266d, content=<a href='/topic/show?id=8c36934354a' target=_blank style='color:#2F92EE;'>#转移性胰腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93435, encryptionId=8c36934354a, topicName=转移性胰腺癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5002500055, createdName=124986d2m09暂无昵称, createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1573365, encodeId=978c15e3365af, content=<a href='/topic/show?id=93a11285330' target=_blank style='color:#2F92EE;'>#NK细胞疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12853, encryptionId=93a11285330, topicName=NK细胞疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e9715863942, createdName=feather83, createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=)]
    2020-02-09 ms2999106592497887

    #肿瘤根除#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1683698, encodeId=2aca16836985d, content=<a href='/topic/show?id=c2fc6228167' target=_blank style='color:#2F92EE;'>#根除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62281, encryptionId=c2fc6228167, topicName=根除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=07d627990740, createdName=风铃830, createdTime=Thu Nov 19 18:24:00 CST 2020, time=2020-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1796510, encodeId=85831e965106b, content=<a href='/topic/show?id=ec8f18029a2' target=_blank style='color:#2F92EE;'>#T细胞激活剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18029, encryptionId=ec8f18029a2, topicName=T细胞激活剂)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIOca9icPByKxo3ZRUrvuibf7tWt7EScQ1NEiaKy4NCUctSU2jDjOayLicDIaicwUxaQhJ1SZKdEevgjRg/132, createdBy=4f272500131, createdName=若水123, createdTime=Sat Mar 21 20:24:00 CST 2020, time=2020-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051493, encodeId=caef20514930b, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Wed Oct 21 11:24:00 CST 2020, time=2020-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1809201, encodeId=874e180920133, content=<a href='/topic/show?id=2f1a829e75c' target=_blank style='color:#2F92EE;'>#肿瘤根除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82977, encryptionId=2f1a829e75c, topicName=肿瘤根除)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erCiat0j36p5MejdM9yCLtcVcY8WS5VIKuCMqXFNs56U6iacZib5CJvh6mVxGERicM6ZAkl91jMgpcDrw/132, createdBy=37622500012, createdName=ms2999106592497887, createdTime=Sun Feb 09 19:24:00 CST 2020, time=2020-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2086595, encodeId=4c2d208659594, content=<a href='/topic/show?id=c1bd1251583' target=_blank style='color:#2F92EE;'>#NantKwest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12515, encryptionId=c1bd1251583, topicName=NantKwest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e72268, createdName=zhixianchen, createdTime=Mon Mar 09 16:24:00 CST 2020, time=2020-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1386580, encodeId=3203138658002, content=<a href='/topic/show?id=f08293399f9' target=_blank style='color:#2F92EE;'>#转移性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93399, encryptionId=f08293399f9, topicName=转移性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1390226, encodeId=14a913902266d, content=<a href='/topic/show?id=8c36934354a' target=_blank style='color:#2F92EE;'>#转移性胰腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93435, encryptionId=8c36934354a, topicName=转移性胰腺癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5002500055, createdName=124986d2m09暂无昵称, createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1573365, encodeId=978c15e3365af, content=<a href='/topic/show?id=93a11285330' target=_blank style='color:#2F92EE;'>#NK细胞疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12853, encryptionId=93a11285330, topicName=NK细胞疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e9715863942, createdName=feather83, createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=)]
    2020-03-09 zhixianchen

    #NantKwest#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1683698, encodeId=2aca16836985d, content=<a href='/topic/show?id=c2fc6228167' target=_blank style='color:#2F92EE;'>#根除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62281, encryptionId=c2fc6228167, topicName=根除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=07d627990740, createdName=风铃830, createdTime=Thu Nov 19 18:24:00 CST 2020, time=2020-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1796510, encodeId=85831e965106b, content=<a href='/topic/show?id=ec8f18029a2' target=_blank style='color:#2F92EE;'>#T细胞激活剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18029, encryptionId=ec8f18029a2, topicName=T细胞激活剂)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIOca9icPByKxo3ZRUrvuibf7tWt7EScQ1NEiaKy4NCUctSU2jDjOayLicDIaicwUxaQhJ1SZKdEevgjRg/132, createdBy=4f272500131, createdName=若水123, createdTime=Sat Mar 21 20:24:00 CST 2020, time=2020-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051493, encodeId=caef20514930b, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Wed Oct 21 11:24:00 CST 2020, time=2020-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1809201, encodeId=874e180920133, content=<a href='/topic/show?id=2f1a829e75c' target=_blank style='color:#2F92EE;'>#肿瘤根除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82977, encryptionId=2f1a829e75c, topicName=肿瘤根除)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erCiat0j36p5MejdM9yCLtcVcY8WS5VIKuCMqXFNs56U6iacZib5CJvh6mVxGERicM6ZAkl91jMgpcDrw/132, createdBy=37622500012, createdName=ms2999106592497887, createdTime=Sun Feb 09 19:24:00 CST 2020, time=2020-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2086595, encodeId=4c2d208659594, content=<a href='/topic/show?id=c1bd1251583' target=_blank style='color:#2F92EE;'>#NantKwest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12515, encryptionId=c1bd1251583, topicName=NantKwest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e72268, createdName=zhixianchen, createdTime=Mon Mar 09 16:24:00 CST 2020, time=2020-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1386580, encodeId=3203138658002, content=<a href='/topic/show?id=f08293399f9' target=_blank style='color:#2F92EE;'>#转移性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93399, encryptionId=f08293399f9, topicName=转移性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1390226, encodeId=14a913902266d, content=<a href='/topic/show?id=8c36934354a' target=_blank style='color:#2F92EE;'>#转移性胰腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93435, encryptionId=8c36934354a, topicName=转移性胰腺癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5002500055, createdName=124986d2m09暂无昵称, createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1573365, encodeId=978c15e3365af, content=<a href='/topic/show?id=93a11285330' target=_blank style='color:#2F92EE;'>#NK细胞疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12853, encryptionId=93a11285330, topicName=NK细胞疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e9715863942, createdName=feather83, createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=)]
    2020-01-19 1249842em09(暂无昵称)

    #转移性#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1683698, encodeId=2aca16836985d, content=<a href='/topic/show?id=c2fc6228167' target=_blank style='color:#2F92EE;'>#根除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62281, encryptionId=c2fc6228167, topicName=根除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=07d627990740, createdName=风铃830, createdTime=Thu Nov 19 18:24:00 CST 2020, time=2020-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1796510, encodeId=85831e965106b, content=<a href='/topic/show?id=ec8f18029a2' target=_blank style='color:#2F92EE;'>#T细胞激活剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18029, encryptionId=ec8f18029a2, topicName=T细胞激活剂)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIOca9icPByKxo3ZRUrvuibf7tWt7EScQ1NEiaKy4NCUctSU2jDjOayLicDIaicwUxaQhJ1SZKdEevgjRg/132, createdBy=4f272500131, createdName=若水123, createdTime=Sat Mar 21 20:24:00 CST 2020, time=2020-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051493, encodeId=caef20514930b, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Wed Oct 21 11:24:00 CST 2020, time=2020-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1809201, encodeId=874e180920133, content=<a href='/topic/show?id=2f1a829e75c' target=_blank style='color:#2F92EE;'>#肿瘤根除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82977, encryptionId=2f1a829e75c, topicName=肿瘤根除)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erCiat0j36p5MejdM9yCLtcVcY8WS5VIKuCMqXFNs56U6iacZib5CJvh6mVxGERicM6ZAkl91jMgpcDrw/132, createdBy=37622500012, createdName=ms2999106592497887, createdTime=Sun Feb 09 19:24:00 CST 2020, time=2020-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2086595, encodeId=4c2d208659594, content=<a href='/topic/show?id=c1bd1251583' target=_blank style='color:#2F92EE;'>#NantKwest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12515, encryptionId=c1bd1251583, topicName=NantKwest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e72268, createdName=zhixianchen, createdTime=Mon Mar 09 16:24:00 CST 2020, time=2020-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1386580, encodeId=3203138658002, content=<a href='/topic/show?id=f08293399f9' target=_blank style='color:#2F92EE;'>#转移性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93399, encryptionId=f08293399f9, topicName=转移性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1390226, encodeId=14a913902266d, content=<a href='/topic/show?id=8c36934354a' target=_blank style='color:#2F92EE;'>#转移性胰腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93435, encryptionId=8c36934354a, topicName=转移性胰腺癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5002500055, createdName=124986d2m09暂无昵称, createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1573365, encodeId=978c15e3365af, content=<a href='/topic/show?id=93a11285330' target=_blank style='color:#2F92EE;'>#NK细胞疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12853, encryptionId=93a11285330, topicName=NK细胞疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e9715863942, createdName=feather83, createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=)]
    2020-01-19 124986d2m09暂无昵称

    #转移性胰腺癌#

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1683698, encodeId=2aca16836985d, content=<a href='/topic/show?id=c2fc6228167' target=_blank style='color:#2F92EE;'>#根除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=62281, encryptionId=c2fc6228167, topicName=根除)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=07d627990740, createdName=风铃830, createdTime=Thu Nov 19 18:24:00 CST 2020, time=2020-11-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1796510, encodeId=85831e965106b, content=<a href='/topic/show?id=ec8f18029a2' target=_blank style='color:#2F92EE;'>#T细胞激活剂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18029, encryptionId=ec8f18029a2, topicName=T细胞激活剂)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIOca9icPByKxo3ZRUrvuibf7tWt7EScQ1NEiaKy4NCUctSU2jDjOayLicDIaicwUxaQhJ1SZKdEevgjRg/132, createdBy=4f272500131, createdName=若水123, createdTime=Sat Mar 21 20:24:00 CST 2020, time=2020-03-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2051493, encodeId=caef20514930b, content=<a href='/topic/show?id=95f8e042dd' target=_blank style='color:#2F92EE;'>#EST#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7042, encryptionId=95f8e042dd, topicName=EST)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9a6357, createdName=xiangyuzhou971, createdTime=Wed Oct 21 11:24:00 CST 2020, time=2020-10-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1809201, encodeId=874e180920133, content=<a href='/topic/show?id=2f1a829e75c' target=_blank style='color:#2F92EE;'>#肿瘤根除#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82977, encryptionId=2f1a829e75c, topicName=肿瘤根除)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83erCiat0j36p5MejdM9yCLtcVcY8WS5VIKuCMqXFNs56U6iacZib5CJvh6mVxGERicM6ZAkl91jMgpcDrw/132, createdBy=37622500012, createdName=ms2999106592497887, createdTime=Sun Feb 09 19:24:00 CST 2020, time=2020-02-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2086595, encodeId=4c2d208659594, content=<a href='/topic/show?id=c1bd1251583' target=_blank style='color:#2F92EE;'>#NantKwest#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12515, encryptionId=c1bd1251583, topicName=NantKwest)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e72268, createdName=zhixianchen, createdTime=Mon Mar 09 16:24:00 CST 2020, time=2020-03-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1386580, encodeId=3203138658002, content=<a href='/topic/show?id=f08293399f9' target=_blank style='color:#2F92EE;'>#转移性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93399, encryptionId=f08293399f9, topicName=转移性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1ac22500003, createdName=1249842em09(暂无昵称), createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1390226, encodeId=14a913902266d, content=<a href='/topic/show?id=8c36934354a' target=_blank style='color:#2F92EE;'>#转移性胰腺癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=93435, encryptionId=8c36934354a, topicName=转移性胰腺癌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a5002500055, createdName=124986d2m09暂无昵称, createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1573365, encodeId=978c15e3365af, content=<a href='/topic/show?id=93a11285330' target=_blank style='color:#2F92EE;'>#NK细胞疗法#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12853, encryptionId=93a11285330, topicName=NK细胞疗法)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=7e9715863942, createdName=feather83, createdTime=Sun Jan 19 12:24:00 CST 2020, time=2020-01-19, status=1, ipAttribution=)]
    2020-01-19 feather83

    #NK细胞疗法#

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