JACC:急性心梗患者不良预后事件的预测研究

2019-08-31 不详 MedSci原创

目前,对于疑似有急性心梗(AMI)患者进行早期及准确的主要不良事件(MACE)的评估尚未达到临床要求。本研究提出假设:将临床判断和心电图联合高敏心脏肌钙蛋白(hs-cTn)的检测可以进一步提高MACE的预测效果。本研究纳入了急症疑似有AMI的患者,主要终点事件是MACE,包括全因死亡、心脏猝死、AMI、心源性休克、持续性室性心律失常和房室传导阻滞。次要终点事件是MACE+接受早期血运重建的不稳定性

目前,对于疑似有急性心梗(AMI)患者进行早期及准确的主要不良事件(MACE)的评估尚未达到临床要求。本研究提出假设:将临床判断和心电图联合高敏心脏肌钙蛋白(hs-cTn)的检测可以进一步提高MACE的预测效果。

本研究纳入了急症疑似有AMI的患者,主要终点事件是MACE,包括全因死亡、心脏猝死、AMI、心源性休克、持续性室性心律失常和房室传导阻滞。次要终点事件是MACE+接受早期血运重建的不稳定性心绞痛。最终共纳入了3123名患者,与扩展算法相比,hs-ctnt 0/1h算法对更多患者进行了排除试验,而30天的MACE发生率无明显差异。hs-ctnt 0/1h算法预测了更少的阳性患者。在30天的MACE+心绞痛预测方面,hs-ctnt 0/1h算法的阳性预测值更高。

研究结果显示,高敏心脏肌钙蛋白算法更好地平衡了预测MACE的有效性和安全性,而新的联合算法更适合MACE+心绞痛的排他预测。

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    2020-01-16 jyzxjiangqin

    急性心梗患者的治疗。

    0

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    2019-09-27 jyzxjiangqin

    急性心血管疾病临床治疗。

    0

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    2019-12-05 hbwxf
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  6. [GetPortalCommentsPageByObjectIdResponse(id=2049503, encodeId=3f032049503ab, content=<a href='/topic/show?id=5c2e5106290' target=_blank style='color:#2F92EE;'>#心梗患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51062, encryptionId=5c2e5106290, topicName=心梗患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e6a1280, createdName=zhanglin3079, createdTime=Fri Dec 13 09:38:00 CST 2019, time=2019-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=378210, encodeId=2d153e8210f8, content=急性心梗患者的治疗。, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Thu Jan 16 19:22:20 CST 2020, time=2020-01-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=373266, encodeId=f41e3e3266ff, content=急性心血管疾病临床治疗。, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Fri Sep 27 17:29:31 CST 2019, time=2019-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1854494, encodeId=554018544942d, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Dec 05 14:38:00 CST 2019, time=2019-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1308387, encodeId=97a1130838e6e, content=<a href='/topic/show?id=8323522e503' target=_blank style='color:#2F92EE;'>#急性心梗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52275, encryptionId=8323522e503, topicName=急性心梗)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fa4f352, createdName=chenlianhui, createdTime=Mon Sep 02 07:38:00 CST 2019, time=2019-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1326319, encodeId=6c94132631935, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Mon Sep 02 07:38:00 CST 2019, time=2019-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1336393, encodeId=5e601336393b9, content=<a href='/topic/show?id=071820530c5' target=_blank style='color:#2F92EE;'>#不良预后#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=18, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=20530, encryptionId=071820530c5, topicName=不良预后)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c97a2500111, createdName=thinkibmz_44722594, createdTime=Mon Sep 02 07:38:00 CST 2019, time=2019-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=372106, encodeId=12f23e21067e, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Sep 01 14:24:40 CST 2019, time=2019-09-01, status=1, ipAttribution=)]
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    2019-09-01 天地飞扬

    学习

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