JACC:一种有效的继发性二尖瓣反流评估方法

2019-05-23 不详 MedSci原创

目前,指南对于严重继发性二尖瓣反流(sMR)的定量评估方法尚未统一,本研究的目的旨在明确针对sMR复杂性质的改进风险阈值,为正在进行的指导方针争议提供统一的解决方案。本研究纳入了423名接受有指南推荐下药物治疗的心衰患者,并通过有效反流孔面积(EROA)、反流体积(RegVol)和反流分数(RegFrac)来评估患者的sMR。分析结果显示,sMR与患者的5年死亡率呈明显相关性,EROA每增加1-S

目前,指南对于严重继发性二尖瓣反流(sMR)的定量评估方法尚未统一,本研究的目的旨在明确针对sMR复杂性质的改进风险阈值,为正在进行的指导方针争议提供统一的解决方案。

本研究纳入了423名接受有指南推荐下药物治疗的心衰患者,并通过有效反流孔面积(EROA)、反流体积(RegVol)和反流分数(RegFrac)来评估患者的sMR。分析结果显示,sMR与患者的5年死亡率呈明显相关性,EROA每增加1-SD,死亡风险增加1.42(95%[CI]: 1.25-1.63; p < 0.001)。样条曲线分析显示,线性增加的风险可以为风险进行风险,分为低风险组(EROA <20 mm2和RegVol <30 ml)、中等风险组(EROA 20-29 mm2和RegVol 30-44 ml)和高风险组(EROA ≥30 mm2和RegVol ≥45 ml)。在中等风险组,RegFrac ≥50%可作为血流动力学sMR的预测因子,且与不良预后相关(p = 0.017)。

研究结果显示,与现有的算法相比,联合有效反流孔面积、反流体积和反流分数评估方法可以很好地对继发性二尖瓣反流进行危险分层。

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    2020-01-25 feifers
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    2019-11-01 xzw113
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    2019-09-18 hbwxf
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    2019-05-25 wwzzly
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    2019-05-25 feifers
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    2019-05-23 天地飞扬

    学习,谢谢分享!

    0

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