abexinostat治疗肾癌的III期研究:首位中国患者已经入组

2019-09-15 Allan MedSci原创

Xynomic是一家临床阶段的肿瘤药物开发公司,近日宣布,在abexinostat联合pazopanib治疗肾癌的全球关键III期临床试验中,第一位中国患者已经在北京大学肿瘤医院入组,abexinostat联合pazopanib预计成为针对肾细胞癌(RCC)的一线或二线疗法。

Xynomic是一家临床阶段的肿瘤药物开发公司,近日宣布,在abexinostat联合pazopanib治疗肾癌的全球关键III临床试验中,第一位中国患者已经在北京大学肿瘤医院入组,abexinostat联合pazopanib预计成为针对肾细胞癌(RCC)的一线或二线疗法。

abexinostat是基于异羟肟酸的小分子组蛋白去乙酰化酶(HDAC)口服抑制剂。abexinostat联合pazopanib作为局部晚期或转移性RCC患者的一线或二线治疗正在进行全球随机关键性III期试验。目前,该试验正在美国、欧洲和韩国进行。美国FDA已将abexinostatpazopanib一起授予快速通道指定。


原始出处:

http://www.firstwordpharma.com/node/1666348#axzz5zU18ApSM

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abexinostat治疗肾癌的关键试验在中国和欧盟取得里程碑式进展

Xynomic是一家临床阶段的肿瘤药物开发公司,近日宣布,中国、西班牙和波兰当局已批准Xynomic的abexinostat进行关键III期试验的申请,abexinostat将与帕唑帕尼联合用于肾细胞癌(RCC)患者。