JAHA:法洛四联症修复术后住院时间长短的预测因素

2018-05-16 xing.T MedSci原创

由此可见,Fallot四联症修复术后的住院时间部分由患者和手术因素决定。一些因素(例如,有症状新生儿的手术策略)可能可能有所改变。这些结果可能会影响患者的心理咨询、手术方式的选择以及术后护理。

近日,心血管疾病领域权威杂志JAHA上发表了一篇研究文章,研究人员试图明确接受完全修复的Fallot四联症患者与出院时间相关的手术与患者因素。

研究人员对2012年5月1日至2017年6月2日在费城儿童医院接受完整修复的Fallot四联症患者进行了前瞻性队列研究,这些患者具有详细的人口统计学、临床和手术特征的信息。主要结局为出院时间。Cox比例风险模型用于确定受试者出院时间的患者和手术预测因子。研究人员招募了151名受试者,其中男性占62.8%,非西班牙裔白人占65.6%,非西班牙裔黑人占9.9%。出院的中位时间为7天(四分位数范围为4-12)。

该研究中有五例患者死亡,均在新生儿期接受法洛四联症修复术。出生体重越大,出院率越高(风险比[HR]=1.35,95%可信区间(CI)=1.11-1.64),而无肺动脉瓣与肺动脉狭窄(HR=0.27,95%CI=0.08-0.91)、肺动脉瓣闭锁与肺动脉狭窄(HR=0.57,95%CI=0.33-0.97)、主动脉-肺动脉侧支(HR=0.44,95%CI=0.24-0.84)、在新生儿期(<30天)完全修复(HR=0.45,95%CI=0.27-0.75)、超过1次体外循环运行(HR=0.33,95%CI=0.18-0.61)和更长的主动脉交叉钳夹时间(HR=0.88,95%CI=0.79-0.97)与出院率降低有关。

由此可见,Fallot四联症修复术后的住院时间部分由患者和手术因素决定。一些因素(例如,有症状新生儿的手术策略)可能可能有所改变。这些结果可能会影响患者的心理咨询、手术方式的选择以及术后护理。

原始出处:

Laura Mercer‐Rosa,et al. Predictors of Length of Hospital Stay After Complete Repair for Tetralogy of Fallot: A Prospective Cohort Study, JAHA.2018. https://doi.org/10.1161/JAHA.118.008719

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    2018-06-24 jyzxjiangqin

    法洛四联症修复术.

    0

  3. 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    2018-06-11 jyzxjiangqin

    法洛四联症修复术.

    0

  4. 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2018, time=2018-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=316826, encodeId=8c22316826b8, content=法洛四联症修复术后住院时间长短., beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun May 20 07:07:14 CST 2018, time=2018-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264289, encodeId=59261264289b3, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267819, encodeId=a2a3126e819ac, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1407130, encodeId=d14e140e13026, content=<a href='/topic/show?id=d0db264464a' target=_blank style='color:#2F92EE;'>#住院时间#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26446, encryptionId=d0db264464a, topicName=住院时间)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bfbf2593024, createdName=crystal0563, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421500, encodeId=d6391421500a8, content=<a href='/topic/show?id=068c6486e77' target=_blank style='color:#2F92EE;'>#法洛四联症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64867, encryptionId=068c6486e77, topicName=法洛四联症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f87f3671641, createdName=tongyongming, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315724, encodeId=12ab315e245c, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Wed May 16 19:38:05 CST 2018, time=2018-05-16, status=1, ipAttribution=)]
    2018-05-27 jyzxjiangqin

    法洛四联症修复术后的管理.

    0

  5. 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2018, time=2018-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=316826, encodeId=8c22316826b8, content=法洛四联症修复术后住院时间长短., beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun May 20 07:07:14 CST 2018, time=2018-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264289, encodeId=59261264289b3, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267819, encodeId=a2a3126e819ac, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1407130, encodeId=d14e140e13026, content=<a href='/topic/show?id=d0db264464a' target=_blank style='color:#2F92EE;'>#住院时间#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26446, encryptionId=d0db264464a, topicName=住院时间)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bfbf2593024, createdName=crystal0563, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421500, encodeId=d6391421500a8, content=<a href='/topic/show?id=068c6486e77' target=_blank style='color:#2F92EE;'>#法洛四联症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64867, encryptionId=068c6486e77, topicName=法洛四联症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f87f3671641, createdName=tongyongming, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315724, encodeId=12ab315e245c, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Wed May 16 19:38:05 CST 2018, time=2018-05-16, status=1, ipAttribution=)]
    2018-05-20 jyzxjiangqin

    法洛四联症修复术后住院时间长短.

    0

  6. 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2018, time=2018-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=316826, encodeId=8c22316826b8, content=法洛四联症修复术后住院时间长短., beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun May 20 07:07:14 CST 2018, time=2018-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264289, encodeId=59261264289b3, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267819, encodeId=a2a3126e819ac, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1407130, encodeId=d14e140e13026, content=<a href='/topic/show?id=d0db264464a' target=_blank style='color:#2F92EE;'>#住院时间#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26446, encryptionId=d0db264464a, topicName=住院时间)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bfbf2593024, createdName=crystal0563, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421500, encodeId=d6391421500a8, content=<a href='/topic/show?id=068c6486e77' target=_blank style='color:#2F92EE;'>#法洛四联症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64867, encryptionId=068c6486e77, topicName=法洛四联症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f87f3671641, createdName=tongyongming, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315724, encodeId=12ab315e245c, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Wed May 16 19:38:05 CST 2018, time=2018-05-16, status=1, ipAttribution=)]
  7. 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2018, time=2018-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=316826, encodeId=8c22316826b8, content=法洛四联症修复术后住院时间长短., beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160806/IMG57A5698BDB0244113.jpg, createdBy=32a91358059, createdName=jyzxjiangqin, createdTime=Sun May 20 07:07:14 CST 2018, time=2018-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1264289, encodeId=59261264289b3, content=<a href='/topic/show?id=daf1100226fb' target=_blank style='color:#2F92EE;'>#预测因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100226, encryptionId=daf1100226fb, topicName=预测因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a57b78, createdName=朱睿睿, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267819, encodeId=a2a3126e819ac, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8e886, createdName=仁者大医, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1407130, encodeId=d14e140e13026, content=<a href='/topic/show?id=d0db264464a' target=_blank style='color:#2F92EE;'>#住院时间#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26446, encryptionId=d0db264464a, topicName=住院时间)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=bfbf2593024, createdName=crystal0563, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1421500, encodeId=d6391421500a8, content=<a href='/topic/show?id=068c6486e77' target=_blank style='color:#2F92EE;'>#法洛四联症#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=64867, encryptionId=068c6486e77, topicName=法洛四联症)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f87f3671641, createdName=tongyongming, createdTime=Fri May 18 10:07:00 CST 2018, time=2018-05-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=315724, encodeId=12ab315e245c, content=学习了.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7c592194322, createdName=1209e435m98(暂无昵称), createdTime=Wed May 16 19:38:05 CST 2018, time=2018-05-16, status=1, ipAttribution=)]
    2018-05-18 仁者大医
  8. 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    2018-05-16 1209e435m98(暂无昵称)

    学习了.谢谢分享

    0

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