J Aller Cl Imm-Pract:美国孕妇妊娠期间过敏反应的情况分析

2019-05-16 xing.T 网络

由此可见,尽管美国剖腹产和随后给药率增加,但没有证据表明过敏反应有增加的趋势。剖腹产和先前的过敏反应史可以识别有过敏反应风险的女性。并非所有女性都有明确的危险因素,应始终做好准备,以确保在发生这种罕见事件时及时进行治疗。

妊娠期过敏反应是一种罕见的和严重的妊娠并发症。近日,过敏性疾病领域权威杂志Journal of Allergy and Clinical Immunology-In Practice上发表了一篇研究文章,该研究旨在描述发病率和时间趋势,并确定在美国孕妇妊娠期间过敏反应相关住院的潜在风险因素。

在2004-2014年期间,研究人员使用来自美国国家住院病例的ICD-9-CM代码识别妊娠期间所有住院治疗和任何过敏反应的孕妇,并计算了妊娠期间过敏反应的年发病率。Logistic回归模型评估了妊娠期间过敏反应的危险因素,以比值比和95%置信区间表示。 

在2004-2014年期间,妊娠期间每10万例住院期间过敏反应的发生率为3.8(95%CI为3.4-4.2),但发病率没有统计学差异。调整后,有三个因素增加了妊娠期间过敏反应的几率:剖腹产[与非剖腹产相比aOR为4.19(95%CI为3.28-5.35)] 、过敏反应史[与无过敏史相比aOR为4.05(95%CI为2.64-6.23)]、黑人种族[与白色人种相比aOR为1.57(95%CI为1.15-2.15)]和其他种族[与白色人种相比aOR为1.69(95%CI为1.08-2.63)。

由此可见,尽管美国剖腹产和随后给药率增加,但没有证据表明过敏反应有增加的趋势。剖腹产和先前的过敏反应史可以识别有过敏反应风险的女性。并非所有女性都有明确的危险因素,应始终做好准备,以确保在发生这种罕见事件时及时进行治疗。 

原始出处:

Stephen J. McCall,et al.Anaphylaxis in pregnancy in the USA: Risk factors and temporal trends using national routinely collected data.J Aller Cl Imm-Pract. 2019. https://doi.org/10.1016/j.jaip.2019.04.047

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    2019-05-18 膀胱癌
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