Barrett食管,患者女30岁反复恶心、反胃、胸闷7年,如何治疗?

2019-01-04 王伯军 王伯军大夫谈消化

患者女30岁,反复恶心、反胃、胸闷7年,胃镜示:慢性浅表性胃炎伴糜烂,中医、西医多方治疗无效。听说Barrett食管是癌前病变,是否需要手术?是否需要长期用药治疗?

患者女30岁,反复恶心、反、胸闷7年,镜示:慢性浅表性胃炎伴糜烂,中医、西医多方治疗无效。听说Barrett食管是癌前病变,是否需要手术?是否需要长期用药治疗?

病 例

患者女30岁,反复恶心、反胃、胸闷7年。

白天基本还好,只偶尔屁多、口水多,有时恶心!主要是睡觉,午睡也一样,入睡困难,刚开始心脏方面不适,也感觉不到酸味,更像口水往上涌,有时候口水也没有,就是胸部闷、无力、轻飘飘的感觉,胸部以上,现在整个上部有时会牵扯到手臂关节也不适,偶尔手发麻,全身无力,影响睡眠,有时会失眠或者进入浅睡状态但感觉胸部以上不适!曾中医、西医多方治疗无效,很紧张、担心。

每天玩手机时间较长。

曾做过24小时动态心电图、胸部CT、血常规、甲状腺功能、血生化、血肿瘤标志等均正常。胃镜示:慢性浅表性胃炎伴糜烂,Barrett食管。

咨询医生:听说Barrett食管是癌前病变,很严重,我是否需要手术,这种病情是否需要长期用药控制?

回 复

已详细阅读了你发来的病史、资料,认为你主要是胃食管反流病?焦虑状态。Barrett食管存在,但问题不大。你主要是对Barrett食管很担心,我先解释一下Barrett食管:

正常食管是由鳞状上皮覆盖的,呈淡红色。Barrett食管(BE食管)是食管下段的鳞状上皮黏膜被柱状上皮所取代,变成桔红色的黏膜。BE食管的诊断主要根据胃镜和活检病理检查。

BE食管在胃镜下有三种形态:岛型、舌型、环型。

通常认为,环型BE食管可能是由胃食管反流病发展而来,但岛型、舌型BE食管,病因至今尚不清楚,可能与先天因素有关。

BE食管本身并无症状,患者的症状主要由胃食管反流及其伴随的病变引起。

胃食管反流病分为两种:反流性食管炎和胃镜检查阴性的胃食管反流症。这两者的症状都一样,主要是反酸、烧心、胸骨后疼痛或上腹痛。两者的区别主要是有无食管损伤。

BE食管目前被公认为食管腺癌的癌前疾病。但岛型、舌型BE食管不易癌变!环形BE食管容易癌变,病变长度越长癌变几率越高!

BE食管随访:对环型BE食管,病变长度 >1cm者,应加强胃镜随访。但对岛型、舌型BE食管患者,无需胃镜随访。

从你的胃镜图片以及文字描述来看,你是岛型BE食管,表面黏膜光滑,可以说几乎没有癌变可能,不需要担心,不需要随访,也不需要服药治疗。

你现在症状其实不是很明显,偶尔嗳气、屁多,这完全是正常现象,也与进食有关。“胸部以上现在是整个上部有时会牵扯到手臂关节也不适,偶尔手发麻”这很可能玩手机过多有关。必要时做一次胸部CT以排除肺部疾病,尤其肺癌可能。

你现在反复胸部不适,在平卧位时发生,平时不明显。确实平卧时容易发生胃食管反流症状,反流时胃酸刺激食管下段可使口水增多,但反流症状主要表现为烧心、灼痛,你的症状很不典型,可能与紧张焦虑有关,可以进一步做食管24小时酸和动力测定,以明确你胸部不适时食管内酸情况,以此可明确诊断

建 议

1.做24小时食管酸测定,胸部CT。
2.放松心情,多锻炼。睡前3小时不进食,少看手机。
3.劳拉西泮片睡前半小时1粒,以镇静促进睡眠,这对你很有必要。
4.如果24小时食管酸测定明确你平卧时有酸反流的话,可以睡前半小时服雷贝拉唑片20 mg或雷尼替丁片300 mg。

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    2019-07-27 ysjykql
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    2019-01-06 zhouqu_8
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    2019-01-06 yangeasy

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