Semin Arthritis Rheu:类风湿性关节炎女性患者的产科结局

2019-04-24 xiangting MedSci原创

RA患者妊娠不良结局的风险较高,因此需要进行产前和产后监测以减少并发症。

由于未知的原因,类风湿性关节炎患者的生育能力下降。很少有研究涉及RA的妊娠结局。这项研究通过使用最大的住院治疗数据库,旨在确定与一般产科人群比较,RA女性患者妊娠期间并发症的发生率。

通过使用2003-2011医疗成本和利用项目全国住院患者样本,研究人员估算了年龄18-50岁RA女性患者的产科住院人数。比较了RA患者和非RA患者所有妊娠相关入院的人口学特征和院内产科并发症。使用多因素logistic回归分析来获得调整后的比值比。

产科住院治疗总人数为4232万人,其中31,439人为RA患者。RA人群的妊娠年龄(30.5岁)高于对照组(27岁)。调整潜在的混杂因素后,妊娠RA患者高血压、胎膜早破、产前出血、早产、胎儿宫内发育迟缓和剖宫产的患病率明显升高。组间的产后出血患病率和院内死亡风险没有差异。

RA患者妊娠不良结局的风险较高,因此需要进行产前和产后监测以减少并发症。需要进一步的研究来分析这些发现与疾病严重程度、用药和存在其他合并症的相关性。

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    2019-04-26 lmm397
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    2019-04-26 zhaojie88
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    2019-04-24 gcwu82

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