复发难治性ALL的挽救治疗:低强度化疗联合Inotuzumab Ozogamicin

2019-09-16 Allan MedSci原创

根据2019年血液肿瘤学会(SOHO)会议的一项报告,对复发难治性B细胞急性淋巴细胞白血病(ALL)患者中进行首次挽救治疗-低强度化疗联合inotuzumab ozogamicin(INO)是非常有效的。

根据2019血液肿瘤学会(SOHO)会议的一项报告,对复发难治性B细胞急性淋巴细胞白血病ALL)患者中进行首次挽救治疗-低强度化疗联合inotuzumab ozogamicinINO)是非常有效的。在该研究中,总体反应率为92%,3年总反应率为42%,中位无事件生存期为10个月,总生存期为17个月。

德克萨斯大学安德森癌症中心的Nicholas J. Short医师表示:患有复发难治性急性淋巴细胞白血病的患者的治疗结果很差。新药的组合,如inotuzumab ozogamicinblinatumomab,可能会改善预后,特别是在首次挽救治疗中。在这种情况下,反应率和生存率优于单一药剂


原始出处:

http://www.firstwordpharma.com/node/1666439#axzz5zU18ApSM

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encodeId=ff94148e8348c, content=<a href='/topic/show?id=46385651633' target=_blank style='color:#2F92EE;'>#挽救治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56516, encryptionId=46385651633, topicName=挽救治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c02a8374760, createdName=drwjr, createdTime=Wed Sep 18 01:27:00 CST 2019, time=2019-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1528604, encodeId=d50c1528604ab, content=<a href='/topic/show?id=74b798601a1' target=_blank style='color:#2F92EE;'>#难治性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98601, encryptionId=74b798601a1, topicName=难治性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a1ef11916292, createdName=freve, createdTime=Wed Sep 18 01:27:00 CST 2019, time=2019-09-18, status=1, ipAttribution=)]
    2020-01-12 kalseyzl
  5. 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encodeId=ff94148e8348c, content=<a href='/topic/show?id=46385651633' target=_blank style='color:#2F92EE;'>#挽救治疗#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56516, encryptionId=46385651633, topicName=挽救治疗)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c02a8374760, createdName=drwjr, createdTime=Wed Sep 18 01:27:00 CST 2019, time=2019-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1528604, encodeId=d50c1528604ab, content=<a href='/topic/show?id=74b798601a1' target=_blank style='color:#2F92EE;'>#难治性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98601, encryptionId=74b798601a1, topicName=难治性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a1ef11916292, createdName=freve, createdTime=Wed Sep 18 01:27:00 CST 2019, time=2019-09-18, status=1, ipAttribution=)]
    2020-01-03 anan
  6. 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01:27:00 CST 2019, time=2019-09-18, status=1, ipAttribution=)]
    2019-10-25 snf701207
  7. 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01:27:00 CST 2019, time=2019-09-18, status=1, ipAttribution=)]
    2019-09-18 膀胱癌
  8. 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    2019-09-18 freve