Rev Med Virol:目前关于疱疹病毒与种植体周围健康相关的证据

2019-03-25 不详 网络

人疱疹病毒(HHVs)(Epstein-Barr病毒[EBV],人巨细胞病毒[CMV]和单纯疱疹病毒[HSV])在种植体周围健康中的病理作用需要了解。为确定种植体周围炎(PI)患者中HHV的证据权重并证实HHV在种植体周围炎症中的重要性,研究人员检索了包括EMBASE,MEDLINE,Cochrane口腔健康组试验注册和Cochrane中心对照试验注册电子数据库,回顾1964年至2018年11月相

人疱疹病毒(HHVs)(Epstein-Barr病毒[EBV],人巨细胞病毒[CMV]和单纯疱疹病毒[HSV])在种植体周围健康中的病理作用需要了解。

为确定种植体周围炎(PI)患者中HHV的证据权重并证实HHV在种植体周围炎症中的重要性,研究人员检索了包括EMBASE,MEDLINE,Cochrane口腔健康组试验注册和Cochrane中心对照试验注册电子数据库,回顾1964年至2018年11月相关的文章。对PI和健康对照组中HHV的患病率进行了Meta分析。生成了森林图,记录了结果的风险差异(RD)和95%置信区间(CI)。

研究共纳入了五项临床研究。四项临床研究报告了EBV数据,而三项临床研究报告了CMV数据。考虑到这些病毒在PI中的风险,在PI和健康之间注意到CMV的显著异质性(χ2= 53.37,p <0.0001,I2 = 96.25%)和EBV(χ2= 14.14,p = 0.002,I2 = 78.79%)。仅EBV(RD = 0.20,95%CI,0.01-0.40,p = 0.03)的总体RD在两组之间具有统计学差异。与健康的非患病部位相比,PI患者的病毒频率增加。

然而,本研究的结果应该谨慎解释,因为所纳入的研究数量较少,研究之间的异质性较大。

原始出处:

Akram Z, Al-Aali KA, et al., Current weight of evidence of viruses associated with peri-implantitis and peri-implant health: A systematic review and meta-analysis. Rev Med Virol. 2019 Mar 22:e2042. doi: 10.1002/rmv.2042.

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    2019-11-29 huangdf
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  6. [GetPortalCommentsPageByObjectIdResponse(id=2077396, encodeId=de5020e739665, content=<a href='/topic/show?id=cb141845040' target=_blank style='color:#2F92EE;'>#Virol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=18450, encryptionId=cb141845040, topicName=Virol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Fri Nov 29 03:55:00 CST 2019, time=2019-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1702074, encodeId=df971e020747d, content=<a href='/topic/show?id=04b9e4784aa' target=_blank style='color:#2F92EE;'>#种植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=19, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74784, encryptionId=04b9e4784aa, topicName=种植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47e130405619, createdName=huangdf, createdTime=Fri Nov 29 12:55:00 CST 2019, time=2019-11-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1343901, encodeId=386a134390127, content=<a href='/topic/show?id=d512e47853f' target=_blank style='color:#2F92EE;'>#种植体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74785, encryptionId=d512e47853f, topicName=种植体)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/TnzXXl41yf6V8fHrDb5JdtxOgpaY6vplUhHtL8BzDh1xMtcap9H1IOlE8umxPGovhIuVkeGTY26eNUFCFaOheQ/132, createdBy=29702500197, createdName=ms6279672939590805, createdTime=Wed Mar 27 06:55:00 CST 2019, time=2019-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1580423, encodeId=63cb158042306, content=<a href='/topic/show?id=c026e05485f' target=_blank style='color:#2F92EE;'>#疱疹#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70548, encryptionId=c026e05485f, topicName=疱疹)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=2dcf16628144, createdName=ms2694732865965676, createdTime=Wed Mar 27 06:55:00 CST 2019, time=2019-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1609651, encodeId=c10d1609651dd, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Wed Mar 27 06:55:00 CST 2019, time=2019-03-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=363532, encodeId=6c41363532a0, content=学习了,涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Mon Mar 25 19:00:09 CST 2019, time=2019-03-25, status=1, ipAttribution=)]
    2019-03-25 王秀

    学习了,涨知识了!

    0