Neurology:素食饮食与缺血性和出血性卒中发生率的关系

2020-02-27 xing.T MedSci原创

由此可见,素食饮食与缺血性和出血性卒中的风险较低有关。

近日,神经病学领域权威取杂志Neurology上发表了一篇研究文章,该研究旨在明确素食如何影响卒中发病率,并探讨是否通过饮食中维生素B12的摄入来改善这种关联。

随访直到2014年底的Tzu Chi Health研究(队列1,n=5050,于2007–2009年招募)和Tzu Chi素食研究(队列2,n=8302,于2005年招募)中没有卒中的参与者。通过基线时两个队列的食物频率问卷评估饮食。卒中事件和基线合并症是通过国家健康保险研究数据库确定的。对队列1的1528名参与者的亚组进行了血清高半胱氨酸、维生素B12和叶酸的评估。素食饮食与卒中发生率之间的相关性通过以年龄作为时间尺度的Cox回归进行估算,并针对性别、教育程度、吸烟、酗酒、体育锻炼、体重指数(仅针对队列1)、高血压糖尿病、血脂异常和缺血性心脏病进行了调整。

素食者的血清维生素B12含量较低,叶酸和高半胱氨酸含量高于非素食者。在队列1中,在30797人次每年的随访中发生了54起事件。素食者(与非素食者相比)的缺血性卒中风险较低(风险比[HR]为0.26;95%置信区间[CI]为0.08-0.88)。在队列2中,在76797人次每年的随访中发生了121起事件。素食主义者(与非素食者相比)的总体卒中(HR为0.52;95%CI为0.33-0.82)、缺血性卒中(HR为0.41;95%CI为0.19-0.88)和出血性卒中(HR为034;95%CI为0.12-1.00)的风险更低。该研究的探索性分析表明维生素B12的摄入可能会改变素食与总体卒中之间的关联(p相互作用=0.046)。

由此可见,素食饮食与缺血性和出血性卒中的风险较低有关。

原始出处:

Tina H.T. Chiu,et al.Vegetarian diet and incidence of total, ischemic, and hemorrhagic stroke in 2 cohorts in Taiwan.Neurology.2020.https://n.neurology.org/content/early/recent

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    2020-08-06 yinhl1978
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    2020-02-27 健健

    卒中虽然是临床上常见病,溶栓,取栓等血管内治疗也很成熟,但是仍然有很多未知问题有待认知!

    0