JACC:体质量指数与经皮冠脉介入治疗结果的关系

2017-07-04 xiangting MedSci原创

在当代临床实践中,关于BMI升高与PCI后死亡率降低相关性的悖论仍十分明显。

这项研究的目的是探讨经皮冠脉介入(PCI)后体质量指数(BMI)与临床结局之间的关系,并确定需要PCI的不同临床表现与这种关系的相关性。

肥胖是一个日益严重的问题,有研究报告显示与正常BMI相比,肥胖对PCI后的不良结局具有保护作用。

2005年至2013年间,共纳入345,192例参与者。数据来自英国心血管介入学会登记处,死亡率数据通过英国国家统计局获取。进行多元logistic回归以确定BMI组(<18.5,18.5至24.9,25-30>和> 30 kg/m2)与不良住院结局和死亡率之间的关系。

在PCI后30天,BMI升高的患者(BMI 25-30:OR = 0.86 [95%置信区间(CI):0.80-0.93] ;BMI> 30 kg/m 2:0.90 [95%CI:0.82-0.98])。PCI术后1年及PCI术后5年,与正常体重相比,体重指数升高(超重或肥胖)是存活率更高的独立预测指标(1年:OR:0.70 [95%CI:0.67-0.73],0.73 [95%CI:0.69-0.77];5年 OR:0.78 [95%CI:0.75-0.81]和0.88 [95%CI:0.84-0.92] )。根据临床表现(稳定型心绞痛、不稳定型心绞痛或非ST抬高型心梗和ST抬高型心梗),分析观察到相似的死亡率降低。

在当代临床实践中,关于BMI升高与PCI后死亡率降低相关性的悖论仍十分明显。这在稳定的和更急性的临床情况中都可以看到。

原始出处:

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    2017-09-17 hbwxf
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    2017-07-04 清风拂面

    学习了,谢谢分享

    0

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    2017-07-04 杨利洪

    学习了,分享了。

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