Cardiovascular Diabetology:不同强度的联合训练对2型糖尿病患者血管产生有利影响,抓紧动起来吧!!!

2021-08-24 MedSci原创 MedSci原创

糖尿病是心、脑血管疾患的独立危险因素。与非糖尿病人群相比, 糖尿病患者发生心、 脑血管疾病的风险增加2~4倍。有效的体育运动不仅对血糖控制有效,而且对糖尿病患者的心血管并发症的发展也有着重要影响。那么

糖尿病是心、脑血管疾患的独立危险因素。与非糖尿病人群相比, 糖尿病患者发生心、 脑血管疾病的风险增加2~4倍。有效的体育运动不仅对血糖控制有效,而且对糖尿病患者的心血管并发症的发展也有着重要影响。那么,糖尿病病人该如何高效运动才能更好的控制血管病变呢?接下来我们一起看看吧!

背景:定期运动是一种大众都认可的改善2型糖尿病患者血管功能的方法。然而,对2型糖尿病患者的血管结构和功能产生最大获益的运动强度仍不清楚。我们的目的是分析高强度间歇训练(HIIT)联合阻力训练(RT)与中等强度持续训练(MCT)联合阻力训练(RT)对2型糖尿病患者动脉结构和功能指数的影响。

方法:将80例2型糖尿病患者随机分为3组:对照组、HIIT联合RT组和MCT联合RT组。在一年的干预中,每周进行三次锻炼。采用高分辨率超声检查颈总动脉和中心及周围动脉压力来评估动脉结构和功能指数的变化。

结果:在调整性别、基线中重度体力活动(MVPA)和平均动脉压(MAP)变化的模型后,同时使用意向处理分析,MCT组(β=-4.25,P<0.01)和HIIT组(β=-3.61,P<0.01)在颈动脉内膜-中膜厚度(cIMT)上均观察到显著的相互作用。然而,只有HIIT观察从基线到1年的外周动脉硬度指标如颈-桡脉搏波速度(β=-0.10, P= 0.044)、颈远端脉搏波速度(β=-0.14, P<0.01)和扩张系数(β=-0.00, P<0.01)有良好的变化。干预后血流动力学变量未受影响。

                                                                                                             图 意向分析的血液动力学、动脉结构和功能指数

                              注:β是根据性别、基线MVPA和MAP变化进行调整的非标准化系数,有95%置信区间DC:扩张系数;CD PWV:颈远端脉搏波速度;CF PWV:颈-股脉搏波速度;CR PWV颈-桡脉搏波速度;DBP:舒张压

                                    HIIT:高强度间歇训练;IMT:内中膜厚度、MCT中等强度持续训练;SBP:收缩压;SI:刚度指数;VO2peak:峰值摄氧量

                                    *组间差异显著,P<0.05 †组内差异显著,P<0.05

结论:在对2型糖尿病患者进行1年的干预后,MCT组和HIIT组均降低了cIMT,而只有HIIT组改善了外周动脉硬化指数和扩张系数

因此我们认为,HIIT可能是改善2型糖尿病血管并发症有意义的方式

原文出处:

Magalhães JP, Melo X, Correia IR, et al. Effects of combined training with different intensities on vascular health in patients with type 2 diabetes: a 1-year randomized controlled trial. Cardiovasc Diabetol. 2019. 18(1): 34.

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  5. 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  6. 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  7. 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createdBy=03b737453747, createdName=ms1065684921169360, createdTime=Wed Jan 12 20:25:26 CST 2022, time=2022-01-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1639851, encodeId=8c2a16398511a, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Mon Oct 25 15:25:26 CST 2021, time=2021-10-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1761664, encodeId=4d501e6166474, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, 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beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Thu Aug 26 08:25:26 CST 2021, time=2021-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1500955, encodeId=755915009554d, content=<a href='/topic/show?id=a89e410286' target=_blank style='color:#2F92EE;'>#cardiovascular#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4102, encryptionId=a89e410286, topicName=cardiovascular)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f9c69479578, createdName=珙桐, createdTime=Thu Aug 26 08:25:26 CST 2021, time=2021-08-26, status=1, ipAttribution=), 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  8. 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style='color:#2F92EE;'>#运动#</a>是可能逆转<a href='/topic/show?id=4f77e665253' target=_blank style='color:#2F92EE;'>#糖尿病#</a>的,尤其是早期。不同运动形式可能又不一样,也许<a href='/topic/show?id=b33110439329' target=_blank style='color:#2F92EE;'>#间歇性运动#</a>最好, beContent=null, objectType=article, channel=null, level=null, likeNumber=238, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94137, encryptionId=babc9413eb6, topicName=运动), TopicDto(id=76652, encryptionId=4f77e665253, topicName=糖尿病), TopicDto(id=104393, encryptionId=b33110439329, topicName=间歇性运动)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=病毒猎手, createdTime=Tue Aug 24 18:15:35 CST 2021, time=2021-08-24, status=1, ipAttribution=)]
    2021-08-24 misszhang

    谢谢MedSci提供最新的资讯

    0

  9. 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style='color:#2F92EE;'>#运动#</a>是可能逆转<a href='/topic/show?id=4f77e665253' target=_blank style='color:#2F92EE;'>#糖尿病#</a>的,尤其是早期。不同运动形式可能又不一样,也许<a href='/topic/show?id=b33110439329' target=_blank style='color:#2F92EE;'>#间歇性运动#</a>最好, beContent=null, objectType=article, channel=null, level=null, likeNumber=238, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94137, encryptionId=babc9413eb6, topicName=运动), TopicDto(id=76652, encryptionId=4f77e665253, topicName=糖尿病), TopicDto(id=104393, encryptionId=b33110439329, topicName=间歇性运动)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=病毒猎手, createdTime=Tue Aug 24 18:15:35 CST 2021, time=2021-08-24, status=1, ipAttribution=)]
    2021-08-24 120d5e71m96(暂无昵称)

    学习

    0

  10. 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topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Sun Mar 20 18:25:26 CST 2022, time=2022-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383712, encodeId=f0961383e12d0, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Thu Aug 26 08:25:26 CST 2021, time=2021-08-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1475122, encodeId=84a714e512204, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, 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GetPortalCommentsPageByObjectIdResponse(id=1043760, encodeId=a09a1043e60d4, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Tue Aug 24 20:25:26 CST 2021, time=2021-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1011102, encodeId=03e5101110246, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=258a2211002, createdName=120d5e71m96(暂无昵称), createdTime=Tue Aug 24 19:46:49 CST 2021, time=2021-08-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1011075, encodeId=50da10110e551, content=<a href='/topic/show?id=babc9413eb6' target=_blank style='color:#2F92EE;'>#运动#</a>是可能逆转<a href='/topic/show?id=4f77e665253' target=_blank style='color:#2F92EE;'>#糖尿病#</a>的,尤其是早期。不同运动形式可能又不一样,也许<a href='/topic/show?id=b33110439329' target=_blank style='color:#2F92EE;'>#间歇性运动#</a>最好, beContent=null, objectType=article, channel=null, level=null, likeNumber=238, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94137, encryptionId=babc9413eb6, topicName=运动), TopicDto(id=76652, encryptionId=4f77e665253, topicName=糖尿病), TopicDto(id=104393, encryptionId=b33110439329, topicName=间歇性运动)], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20211210/ede9c51184aa4f54ae6c1164cfb8eeac/967dbf3eff2943c7bf3ccfec3a776ab0.JPG, createdBy=a33789389, createdName=病毒猎手, createdTime=Tue Aug 24 18:15:35 CST 2021, time=2021-08-24, status=1, ipAttribution=)]
    2021-08-24 病毒猎手

    #运动#是可能逆转#糖尿病#的,尤其是早期。不同运动形式可能又不一样,也许#间歇性运动#最好

    0

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