创建带有网膜脂肪增强游离皮瓣的生物乳房植入物

2022-04-19 宁咸襄 MedSci原创

患有肌皮或筋膜皮肤软组织炎的女性在乳腺切除术后选择供区进行乳房重建,大多局限于植入物。对于那些不想要或存在基于植入物的重建禁忌症的患者便需要相应的替代物。

患有肌皮或筋膜皮肤软组织炎的女性在乳腺切除术后选择供区进行乳房重建,大多局限于植入物。对于那些不想要或存在基于植入物的重建禁忌症的患者便需要相应的替代物。

从大网膜制作三维乳房丘的一个主要挑战是其平坦、不成形的形状。该研究描述了一种新颖独特的方法,在保留乳头的乳房切除术后,使用包含在无粘膜真皮基质模具内的大网膜脂肪游离皮瓣。

图1 文章来源

该文章报告了一种新的技术,使用大网膜脂肪增强的游离皮瓣来创建一个与乳房植入物具有相似形状和投影的自体乳房。

2019年至2020年期间,研究者确定了三名需要单侧重建的乳腺癌患者。受试者都没有足够的传统自体部位,并且都反对使用植入物。为此,研究者行保留乳头的乳房切除术,并在腹腔镜下取大网膜,进行体外脂肪移植,然后将其包裹在脱细胞真皮基质中进行微血管吻合。

图2所有患者乳房、大网膜、脂肪移植物和大网膜脂肪增强无细胞真皮基质游离皮瓣的天然和重建重量的比较

结果表明,三名患者的体重指数分别为17.6、25和28.3 kg/m2。每个个体的乳房切除术标本和相应的大网膜加脂肪移植重量分别为113.7/228、271/293和270/360克。

未发生术后并发症。重建的乳房仍然柔软。在术后6个月时,受试者乳房体积稳定,没有脂肪坏死的迹象。

这是第一例使用大网膜脂肪游离皮瓣成功进行结构性乳房重建的报道。这项技术使乳房看起来自然,投影与植入物相当,美学效果优于之前使用网膜瓣的尝试。对于那些希望自体乳房重建但不想或不符合更传统自体乳房重建方法的患者,它提供了一种可靠的自体替代物。

 

文章来源:

Nguyen, Dung H. M.D., Pharm.D.; Ma, Irene T. M.D.; Choi, Youna K. M.D.; Zak, Yulia M.D.; Dua, Monica M. M.D.; Wapnir, Irene L. M.D. Creating a Biological Breast Implant with an Omental Fat-Augmented Free Flap, Plastic and Reconstructive Surgery: April 2022 - Volume 149 - Issue 4 - p 832-835

doi: 10.1097/PRS.0000000000008963

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    2022-04-26 1235bd28m70暂无昵称

    认真***

    0

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    2022-04-19 ms5000000462690030

    有趣

    0

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