JAHA:自发性冠状动脉夹层患者偏头痛的患病率及临床因素分析

2018-12-13 xing.T MedSci原创

由此可见,许多SCAD患者有偏头痛病史。偏头痛的SCAD患者在发生SCAD时较年轻;在那些进行过影像学检查的患者中有更多的动脉瘤、假性动脉瘤和夹层患者;并且更经常报告有抑郁症和SCAD后胸痛的病史。

自发性冠状动脉夹层(SCAD)是急性冠状动脉综合征的一个原因,主要发生在没有血管危险因素的女性身上。许多人有偏头痛的病史,但对这种关联却知之甚少。近日,血管疾病领域权威杂志JAHA上发表了一篇研究文章,该研究旨在确定SCAD患者的偏头痛患病率,并根据偏头痛病史评估临床因素的差异。

研究人员使用经冠状动脉血管造影证实的SCAD患者组成的梅奥诊所SCAD“虚拟”多中心数据进行了队列研究。研究人员对参与者提供的数据和记录进行了审查,收集偏头痛、危险因素、SCAD详细信息、治疗和结局的数据。

在585名患者(96%女性)中,236名患者有偏头痛病史;偏头痛的终生和1年患病率分别为40%和26%。偏头痛在SCAD女性中的比例比文献报道的女性人群中更高(42% vs. 24%,P<0.0001; 42% vs. 33%,P<0.0001)。在所有SCAD患者中,偏头痛患者更可能是女性(99.6% vs. 94%; P=0.0002)、发生SCAD的年龄较小(45.2±9.0岁 vs. 47.6±9.9岁; P=0.0027)、抑郁症(27% vs. 17%; P=0.025)、SCAD1个月后复发性胸痛(50% vs. 39%; P=0.035)。在评估的患者中,有动脉瘤、假性动脉瘤或夹层的比例较高(28% vs. 18%; P=0.018)。对于偏头痛与非偏头痛患者,5年SCAD复发比例无显著差异(15% vs. 19%; P=0.39)。

由此可见,许多SCAD患者有偏头痛病史。偏头痛的SCAD患者在发生SCAD时较年轻;在那些进行过影像学检查的患者中有更多的动脉瘤、假性动脉瘤和夹层患者;并且更经常报告有抑郁症和SCAD后胸痛的病史。

原始出处:

Susan N. Kok.et al.Prevalence and Clinical Factors of Migraine in Patients With Spontaneous Coronary Artery Dissection.JAHA.2018.https://www.ahajournals.org/doi/full/10.1161/JAHA.118.010140

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    2019-10-12 howi
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    2018-12-17 荒郊野树

    略略略热了热啊

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=2040552, encodeId=5271204055242, content=<a href='/topic/show?id=b5b830850e7' target=_blank style='color:#2F92EE;'>#冠状动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30850, encryptionId=b5b830850e7, topicName=冠状动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Mon Apr 29 18:58:00 CST 2019, time=2019-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2007578, encodeId=7f7f200e57868, content=<a href='/topic/show?id=1ec222e50e6' target=_blank style='color:#2F92EE;'>#临床因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22750, encryptionId=1ec222e50e6, topicName=临床因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sat Oct 12 16:58:00 CST 2019, time=2019-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355626, encodeId=671435562653, content=略略略热了热啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq08fBE4ne4yAYXulsHUXiafWXWEQ1kDkMHtT9loagc1nibPCrwjpESVuPO4De8QTeajAic31lDPfjuA/132, createdBy=92ce1931739, createdName=荒郊野树, createdTime=Mon Dec 17 06:41:20 CST 2018, time=2018-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355557, encodeId=fadc35555e3d, content=提裤子正楷字, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq08fBE4ne4yAYXulsHUXiafWXWEQ1kDkMHtT9loagc1nibPCrwjpESVuPO4De8QTeajAic31lDPfjuA/132, createdBy=92ce1931739, createdName=荒郊野树, createdTime=Sun Dec 16 11:50:40 CST 2018, time=2018-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250587, encodeId=dfbc125058e64, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Sat Dec 15 10:58:00 CST 2018, time=2018-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268006, encodeId=da081268006af, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sat Dec 15 10:58:00 CST 2018, time=2018-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519587, encodeId=1cf8151958ef9, content=<a href='/topic/show?id=b63a3323558' target=_blank style='color:#2F92EE;'>#动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33235, encryptionId=b63a3323558, topicName=动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae5711287462, createdName=mhzhuang@stu.e, createdTime=Sat Dec 15 10:58:00 CST 2018, time=2018-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530581, encodeId=969415305817c, content=<a href='/topic/show?id=ed4a860e872' target=_blank style='color:#2F92EE;'>#自发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86078, encryptionId=ed4a860e872, topicName=自发性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=584a12117168, createdName=sodoo, createdTime=Sat Dec 15 10:58:00 CST 2018, time=2018-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355326, encodeId=d61e355326e7, content=好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Thu Dec 13 20:23:59 CST 2018, time=2018-12-13, status=1, ipAttribution=)]
    2018-12-16 荒郊野树

    提裤子正楷字

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2040552, encodeId=5271204055242, content=<a href='/topic/show?id=b5b830850e7' target=_blank style='color:#2F92EE;'>#冠状动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30850, encryptionId=b5b830850e7, topicName=冠状动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=9d8a96, createdName=doctorzheng, createdTime=Mon Apr 29 18:58:00 CST 2019, time=2019-04-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2007578, encodeId=7f7f200e57868, content=<a href='/topic/show?id=1ec222e50e6' target=_blank style='color:#2F92EE;'>#临床因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22750, encryptionId=1ec222e50e6, topicName=临床因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Sat Oct 12 16:58:00 CST 2019, time=2019-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355626, encodeId=671435562653, content=略略略热了热啊, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq08fBE4ne4yAYXulsHUXiafWXWEQ1kDkMHtT9loagc1nibPCrwjpESVuPO4De8QTeajAic31lDPfjuA/132, createdBy=92ce1931739, createdName=荒郊野树, createdTime=Mon Dec 17 06:41:20 CST 2018, time=2018-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355557, encodeId=fadc35555e3d, content=提裤子正楷字, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/DYAIOgq83eq08fBE4ne4yAYXulsHUXiafWXWEQ1kDkMHtT9loagc1nibPCrwjpESVuPO4De8QTeajAic31lDPfjuA/132, createdBy=92ce1931739, createdName=荒郊野树, createdTime=Sun Dec 16 11:50:40 CST 2018, time=2018-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1250587, encodeId=dfbc125058e64, content=<a href='/topic/show?id=7d6f52988e1' target=_blank style='color:#2F92EE;'>#患病率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=52988, encryptionId=7d6f52988e1, topicName=患病率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f49517, createdName=xinmeili, createdTime=Sat Dec 15 10:58:00 CST 2018, time=2018-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1268006, encodeId=da081268006af, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Sat Dec 15 10:58:00 CST 2018, time=2018-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1519587, encodeId=1cf8151958ef9, content=<a href='/topic/show?id=b63a3323558' target=_blank style='color:#2F92EE;'>#动脉夹层#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=33235, encryptionId=b63a3323558, topicName=动脉夹层)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ae5711287462, createdName=mhzhuang@stu.e, createdTime=Sat Dec 15 10:58:00 CST 2018, time=2018-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530581, encodeId=969415305817c, content=<a href='/topic/show?id=ed4a860e872' target=_blank style='color:#2F92EE;'>#自发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86078, encryptionId=ed4a860e872, topicName=自发性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=584a12117168, createdName=sodoo, createdTime=Sat Dec 15 10:58:00 CST 2018, time=2018-12-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=355326, encodeId=d61e355326e7, content=好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Thu Dec 13 20:23:59 CST 2018, time=2018-12-13, status=1, ipAttribution=)]
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    2018-12-15 zhaohui6731
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    2018-12-15 sodoo
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    2018-12-13 lietome2

    好文,值得点赞!认真学习,应用于实践!谢谢分享给广大同好!

    0

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