Neurology:机械取栓后血压水平与大血管闭塞卒中患者的预后!

2017-07-08 xing.T MedSci原创

MT后最大SBP水平较高与增加的3个月死亡率和LVO患者功能依赖独立相关。与允许性高血压相比,适度的血压控制也可以降低3个月死亡率。

评估机械取栓(MT)后血压(BP)水平对大血管闭塞(LVO)患者早期结局影响的数据十分有效。近日,神经病学领域权威取杂志Neurology上发表了一篇研究文章,研究人员试图探讨MT后BP时程变化与LVO患者早期结局之间的相关性。研究人员对连续就诊的进行MT治疗的LVO患者进行了评估。MT后24小时内记录每小时的收缩压(SBP)和舒张压(DBP)以及确定最大SBP和DBP水平。MT后完全再灌注的LVO患者基于MT后达到的目标血压而分为3组:经静脉溶栓治疗前<140/90mmHg(强化)、<160/90mmHg(中等)和<220/110mmHg或<180/105mmHg(允许性高血压)。三个月的功能独立性是通过改良Rankin量表评分为0–2分来定义。研究人员共前瞻性地评估了217例急性缺血性脑卒中的LVO患者。MT后首个24小时内最大SBP增加10mmHg与患者3个月功能独立的可能性较低(P=0.001)(比值比[OR]为0.70;95%可信区间[CI]为0.56-0.87)和患者3个月死亡率较高(OR为1.49;95%CI为1.18-1.88)相关,调整了潜在的混杂因素后。

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    2017-10-12 yinhl1978
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encryptionId=7f6443986ec, topicName=大血管)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=caff31165455, createdName=kkunny, createdTime=Sun Apr 22 17:13:00 CST 2018, time=2018-04-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1720187, encodeId=3bb41e2018785, content=<a href='/topic/show?id=915c3604e6b' target=_blank style='color:#2F92EE;'>#卒中患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=36047, encryptionId=915c3604e6b, topicName=卒中患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=940232842333, createdName=wangyang7969, createdTime=Sun Aug 27 12:13:00 CST 2017, time=2017-08-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=221149, encodeId=c9542211494e, content=不错的方式,努力学习,刻苦专研,不断总结出来新经验。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue Jul 11 22:11:11 CST 2017, time=2017-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220789, encodeId=92e0220e893a, content=好多灌水评论,有必要吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4cd1660740, createdName=dachengl, createdTime=Mon Jul 10 19:23:35 CST 2017, time=2017-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1479050, encodeId=4b1514e905049, content=<a href='/topic/show?id=b97f3800ee0' target=_blank style='color:#2F92EE;'>#取栓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38007, encryptionId=b97f3800ee0, topicName=取栓)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=99077483919, createdName=1249862am74(暂无昵称), createdTime=Mon Jul 10 14:13:00 CST 2017, time=2017-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1578892, encodeId=523115e889275, content=<a href='/topic/show?id=80286123908' target=_blank style='color:#2F92EE;'>#机械取栓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61239, encryptionId=80286123908, topicName=机械取栓)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=de0216462203, createdName=ms2186806800017884, createdTime=Mon Jul 10 14:13:00 CST 2017, time=2017-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220712, encodeId=f2b8220e1265, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuCl4zaE0zq0kFsKQmg3vef7gFticiaFX50TWZibZibNHbk3YSJ5uSh1a0DcUiaVIHkoe2Om3eYg7oUTlf/0, createdBy=442c2063958, createdName=海棠胜雪, createdTime=Mon Jul 10 12:53:38 CST 2017, time=2017-07-10, status=1, ipAttribution=)]
    2018-04-22 kkunny
  5. 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  6. 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topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Tue Jul 11 22:11:11 CST 2017, time=2017-07-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220789, encodeId=92e0220e893a, content=好多灌水评论,有必要吗?, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e4cd1660740, createdName=dachengl, createdTime=Mon Jul 10 19:23:35 CST 2017, time=2017-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1479050, encodeId=4b1514e905049, content=<a href='/topic/show?id=b97f3800ee0' target=_blank style='color:#2F92EE;'>#取栓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=38007, encryptionId=b97f3800ee0, topicName=取栓)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=99077483919, createdName=1249862am74(暂无昵称), createdTime=Mon Jul 10 14:13:00 CST 2017, time=2017-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1578892, encodeId=523115e889275, content=<a href='/topic/show?id=80286123908' target=_blank style='color:#2F92EE;'>#机械取栓#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61239, encryptionId=80286123908, topicName=机械取栓)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=de0216462203, createdName=ms2186806800017884, createdTime=Mon Jul 10 14:13:00 CST 2017, time=2017-07-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=220712, encodeId=f2b8220e1265, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuCl4zaE0zq0kFsKQmg3vef7gFticiaFX50TWZibZibNHbk3YSJ5uSh1a0DcUiaVIHkoe2Om3eYg7oUTlf/0, createdBy=442c2063958, createdName=海棠胜雪, createdTime=Mon Jul 10 12:53:38 CST 2017, time=2017-07-10, status=1, ipAttribution=)]
    2017-07-11 虈亣靌

    不错的方式,努力学习,刻苦专研,不断总结出来新经验。

    0

  7. 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beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuCl4zaE0zq0kFsKQmg3vef7gFticiaFX50TWZibZibNHbk3YSJ5uSh1a0DcUiaVIHkoe2Om3eYg7oUTlf/0, createdBy=442c2063958, createdName=海棠胜雪, createdTime=Mon Jul 10 12:53:38 CST 2017, time=2017-07-10, status=1, ipAttribution=)]
    2017-07-10 dachengl

    好多灌水评论,有必要吗?

    0

  8. 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  9. 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    2017-07-10 海棠胜雪

    学习了

    0

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很少有数据可以解释急性缺血性卒中患者接受机械血栓(MT)高血糖和结果之间的关联。研究人员在Flow Restoration With the Intention for Thrombectomy (SWIFT)多中心随机试验根据MT后再灌注状态调查了高血糖是否会影响MT治疗后患者的预后。研究人员分析了作为连续变量的葡萄糖水平和作为二元变量的高血糖(>140mg/dL葡萄糖)和几个感兴趣的结果

JAMA Neurol:急性缺血性脑卒中患者机械取栓前,静脉溶栓的益处不大

急性缺血性脑卒中患者经常出现大血管闭塞,而机械取栓(Mechanical thrombectomy,MT)改善了急性缺血性脑卒中(AIS)患者的临床结局。然而不知道静脉溶栓(IVT)对MT患者是否有益。最近发表在JAMA Neurol上的一项研究探讨了在MT(支架取栓)之前进行IVT治疗是否有益。这是一项事后分析,使用的数据来自291例机械取栓的病人,这些患者来自2个大的多中心的前瞻性评价AIS患

JACC:急性缺血性脑卒中患者机械取栓治疗可降低全因死亡率

急性缺血性脑卒中是世界范围内严重的伤残和死亡的主要原因。个体的随机临床试验显示,在急性缺血性卒中患者的治疗管理中,常规护理后进行机械取栓,与单独常规治疗(即静脉溶栓)相比,可能会为患者带来好处。本研究的目的是系统地确定,如果常规治疗后进行机械取栓是否会为大动脉闭塞引起的急性缺血性脑卒中患者带来更好的预后。研究人员进行了比较常规治疗后机械取栓与单纯常规治疗急性缺血性中风的随机试验。随机效应的总风险比

PLoS One:急性缺血性卒中机械取栓后出血、死亡及预后的预测因子有哪些?

背景:血管内机械血栓切除术是一种新兴的有前景治疗急性缺血性卒中的方法,并且有一些优势。然而,Solitaire取栓后的临床预后的预测数据尚不清楚。研究者试图找出应用Solitaire取栓后,急性缺血性卒中患者临床预后的预测因素。方法:研究者对2010年12月到2013年12月急性缺血性卒中患者进行回顾性分析,这些患者进行了Solitaire取栓质量。研究者评估了人口学资料的影响,3个月不良预后(m

Stroke:颈动脉颅内段钙化与接受机械取栓患者的血运重建有关吗?

在急性脑卒中患者在机械取栓前较大量的颈动脉颅内段钙化是糟糕的术后动脉血运重建和较差的功能预后的一个指标。