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Radiology：肝癌都这么大了，如何治疗才能提高生存期呢？

2018-05-21 shaosai MedSci原创

索拉菲尼经动脉化学栓塞肝细胞肝癌
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本研究旨在验证索拉菲尼联合经动脉化学栓塞（TACE）和射频消融（RFA）（S-TACE-RFA）治疗中或大肝细胞肝癌(HCC)的安全性和疗效，并将结果发表在Radiology上。

本研究旨在验证索拉菲尼联合经动脉化学栓塞（TACE）和射频消融（RFA）（S-TACE-RFA）治疗中或大肝细胞肝癌(HCC)的安全性和疗效，并将结果发表在Radiology上。

本研究纳入了有中或大HCC且行S-TACE-RFA或联合TACE和RFA（TACE-RFA）治疗的患者。索拉菲尼治疗开始于TACE3-5天后，RFA开始于TACE后1-2周。比较行S-TACE-RFA和TACE-RFA两组患者治疗并发症，无复发生存期（RFS）

和整体生存期（OS）。

结果为，共有174例患者行S-TACE-RFA或TACE-RFA治疗，其中有106例符合纳入标准。共有40例行S-TACE-RFA，66例行TACE-RFA。S-TACE-RFA组患者要较TACE-RFA组有更长的RFS(中位数为24.0 vs 10.0 months； P = .04)、更好的OS(中位数为63.0 vs 36.0 months， P = .048)。S-TACE-RFA和甲胎蛋白水平是生存期的独立预测指标。S-TACE-RFA组并发症与TACE-RFA组频率相似(22.5% vs 18.2%， P = .59)。

本研究表明，S-TACE-RFA与TACE-RFA疗法相比，会延长中或大HCC患者的RFS和改善OS。

原始出处：


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    2018-11-19 foxv3羽翼

    学习了，谢谢分享

    0

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    2018-11-14 foxv3羽翼

    学习了

    0

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    2018-06-10 如草

    谢谢分享

    0

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    2018-05-25 吴教授

    学习了学习了

    0

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    2018-05-24 zb1235672

    好知识值得借鉴!

    0

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    2018-05-23 仁者大医

    #生存期#

    0

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    2018-05-23 121832a9m88暂无昵称

    学习了

    0

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    2018-05-23 神功盖世

    阅

    0

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    2018-05-23 sunfeifeiyang

    学习

    0

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    2018-05-22 1821e83055m

    不错的方法

    0

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