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HEART：非缺血性心肌病的全新荟萃分析！

2017-10-14 MedSci MedSci原创

非缺血性心肌病除颤
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一项丹麦的研究通过评估了ICD对非缺血性心脏收缩期心力衰竭患者死亡率（DANISH）疗效的数据表明，植入式心律转复除颤器（ICD）减少了心源性猝死，但是其并没有降低非缺血性心肌病（NICM）患者的总死亡率。近期，一项发表在杂志HEART上的研究进行了荟萃分析，以评估ICD治疗对NICM患者死亡率的影响。此项研究系统地搜索了ICD对NICM患者结局的影响。此项分析将随机分配到ICD的患者与随机分为无

一项丹麦的研究通过评估了ICD对非缺血性心脏收缩期心力衰竭患者死亡率（DANISH）疗效的数据表明，植入式心律转复除颤器（ICD）减少了心源性猝死，但是其并没有降低非缺血性心肌病（NICM）患者的总死亡率。近期，一项发表在杂志HEART上的研究进行了荟萃分析，以评估ICD治疗对NICM患者死亡率的影响。此项研究系统地搜索了ICD对NICM患者结局的影响。此项分析将随机分配到ICD的患者与随机分为无ICD的患者进行了比较，并检查总体死亡率的终点。此项研究结果显示：共确定了六项初级预防试验和两项二级预防试验，均符合预先规定的检测标准。使用固定效应模型，初级预防试验分析显示ICD治疗总体死亡率降低（RR 0.76，95％CI 0.65至0.91）。此项研究结果表明：尽管此项更新的荟萃分析显示了ICD治疗的生存益处，但是通过纳入DANISH试验（其既是分析试验中最大的也是最近的试验），实质上减弱了这种效果，由此表明ICD的合并益处可能反映老年试验中猝死的风险，其包括按当代标准治疗的患者。因此，这些数据必须谨慎解释。DANISH试验的结果强调，NICM患者的一级预防ICD没有“一刀切”的指标，临

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    2018-07-17 fangcong

    #荟萃分析#

    0

  2. 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    2018-08-02 zhaojie88

    #荟萃#

    0

  3. 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    2017-12-17 guihongzh

    #缺血性#

    0

  4. 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likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/07/8c1e5a0085f3b74f3a4ab58a38a3d487.jpg, createdBy=b33e2159612, createdName=2227437833_79976374, createdTime=Sun Oct 15 08:32:13 CST 2017, time=2017-10-15, status=1, ipAttribution=)]
    2017-10-16 131****2916

    不错的文章值得推荐一下

    0

  5. 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likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/07/8c1e5a0085f3b74f3a4ab58a38a3d487.jpg, createdBy=b33e2159612, createdName=2227437833_79976374, createdTime=Sun Oct 15 08:32:13 CST 2017, time=2017-10-15, status=1, ipAttribution=)]
    2017-10-16 131****1460

    学习了受益匪浅

    0

  6. 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likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/07/8c1e5a0085f3b74f3a4ab58a38a3d487.jpg, createdBy=b33e2159612, createdName=2227437833_79976374, createdTime=Sun Oct 15 08:32:13 CST 2017, time=2017-10-15, status=1, ipAttribution=)]
    2017-10-16 zhaojie88

    #ART#

    0

  7. 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likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/07/8c1e5a0085f3b74f3a4ab58a38a3d487.jpg, createdBy=b33e2159612, createdName=2227437833_79976374, createdTime=Sun Oct 15 08:32:13 CST 2017, time=2017-10-15, status=1, ipAttribution=)]
    2017-10-16 huanbaofeng

    #缺血性心肌病#

    0

  8. 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likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/07/8c1e5a0085f3b74f3a4ab58a38a3d487.jpg, createdBy=b33e2159612, createdName=2227437833_79976374, createdTime=Sun Oct 15 08:32:13 CST 2017, time=2017-10-15, status=1, ipAttribution=)]
    2017-10-16 slcumt

    #HEART#

    0

  9. 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    2017-10-16 爆笑小医

    #肌病#

    0

  10. 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    2017-10-15 2227437833_79976374

    很好很好很好

    0

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