IBD: 炎症性肠病孕妇比一般人群更有可能进行剖宫产分娩

2020-11-07 MedSci原创 MedSci原创

包括克罗恩氏病(CD)和溃疡性结肠炎(UC)在内的炎症性肠病(IBD)是成年人中常见的自身免疫性疾病。由于许多患有这些疾病的妇女处于其生育的主要年龄.

包括克罗恩氏病(CD)和溃疡性结肠炎(UC)在内的炎症性肠病(IBD)是成年人中常见的自身免疫性疾病。由于许多患有这些疾病的妇女处于其生育的主要年龄,因此存在关于怀孕期间分娩方式正确以及哪些与疾病相关的变量和药物可能影响该决定的问题。数据表明,患有炎症性肠病(IBD)的孕妇比一般人群更有可能进行剖宫产和不良妊娠结局。这项研究的目的是描述与其他自身免疫性疾病患者和一般人群相比,IBD患者的剖宫产率和不良妊娠结局的发生率。

 

研究人员从数据库中确定了IBD的孕妇,非IBD自身免疫性疾病的孕妇和对照患者。回顾性记录基线人口统计学,疾病特征,药物使用和分娩结果。主要结局是剖宫产率。次要结局包括计划内和计划外剖宫产,分娩并发症,早产和胎儿并发症的发生率。

 

研究人员将93名IBD妇女与376名对照患者年龄相匹配。还确定了38名患有其他自身免疫性疾病的妇女。与对照组患者(31%;P <0.0001)相比,IBD妇女的剖宫产率更高(47%),但与其他自身免疫性疾病的妇女相比则没有。在IBD队列中,针对IBD相关因素的剖宫产分娩率很高。患有IBD的妇女的不良分娩或胎儿结局率没有增加。

 

研究最后作者说道:患有IBD的妇女比一般人群的剖宫产率更高,并且比率与患有其他自身免疫性疾病的妇女相似。

 

 

原始出处 :

Taylor Geisman. Et al. Delivery Outcomes of Pregnant Patients With Inflammatory Bowel Diseases Compared With the General Population and With Women With Other Autoimmune Diseases at a Tertiary Care Center. Inflammatory Bowel Diseases.2020.

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    2020-11-09 bnurmamat
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    2020-11-09 linlin2312
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