Nutr Metab Cardiovasc Dis:静息心率较高 坏处不胜枚举

2017-07-11 张琪 吴星 环球医学

2017年6月,发表在《Nutr Metab Cardiovasc Dis》的一项由挪威和美国科学家进行的前瞻性研究的系统评价和荟萃分析,考察了静息心率与心血管疾病、肿瘤及全因死亡风险的相关性。

2017年6月,发表在《Nutr Metab Cardiovasc Dis》的一项由挪威和美国科学家进行的前瞻性研究的系统评价和荟萃分析,考察了静息心率与心血管疾病、肿瘤及全因死亡风险的相关性。

背景和目的:流行病学研究报告,静息心率较高,心血管疾病、癌症及全因死亡率风险增加。然而现有证据不一致。性别差异、混杂因素校正,以及亚临床疾病的潜在影响尚不清楚。一项既往荟萃分析遗漏了大量研究,并且此前没有总结过房颤的数据。因此,研究者旨在一项前瞻性研究的系统评价和荟萃分析中,阐明这些相关性。

方法和结果:检索PubMed和Embase中截至2017年3月29日的数据。使用随机效果模型,计算总RRs和95%置信区间(CIs)。共纳入87项研究。冠状动脉心脏病静息心率每分钟加快10次时,总RR值为1.07(95% CI:1.05~1.10,I2=61.9%,n=31),心源性猝死为1.09(95% CI:1.00~1.18,I2=62.3%,n=5),心衰为1.18(95% CI:1.10~1.27,I2=74.5%,n=8),房颤为0.97(95% CI:0.92~1.02,I2=91.4%,n=9),总卒中为1.06(95% CI:1.02~1.10,I2=59.5%,n=16),心血管疾病为1.15(95% CI:1.11~1.18,I2=84.3%,n=35),总癌症为1.14(95% CI:1.06~1.23,I2=90.2%,n=12),全因死亡率为1.17(95% CI:1.14~1.19,I2=94.0%,n=48)。全部结局,除了房颤,都存在正向剂量应答关系,且为J形相关性。

结论:本荟萃分析发现,静息心率较高,冠心病、心源性猝死、心衰、房颤、卒中、心血管疾病、总癌症和全因死亡率风险增加。

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    2017-10-01 quxin068
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    2017-10-20 一闲
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    2018-01-07 guojianrong
  5. [GetPortalCommentsPageByObjectIdResponse(id=1938735, encodeId=996d1938e352f, content=<a href='/topic/show?id=1c292818fd' target=_blank style='color:#2F92EE;'>#ASC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2818, encryptionId=1c292818fd, topicName=ASC)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=74808, createdName=quxin068, createdTime=Sun Oct 01 20:31:00 CST 2017, time=2017-10-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2012314, encodeId=0e7720123144d, content=<a href='/topic/show?id=7d69598468' target=_blank style='color:#2F92EE;'>#Dis#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5984, encryptionId=7d69598468, topicName=Dis)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Tue May 29 13:31:00 CST 2018, time=2018-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1896110, encodeId=0df918961106b, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Fri Oct 20 21:31:00 CST 2017, time=2017-10-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887692, encodeId=7e65188e6924d, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Sun Jan 07 15:31:00 CST 2018, time=2018-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1579025, encodeId=a6e015e9025b8, content=<a href='/topic/show?id=3007990e6f0' target=_blank style='color:#2F92EE;'>#静息心率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99076, encryptionId=3007990e6f0, topicName=静息心率)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=692416492771, createdName=12498761m61暂无昵称, createdTime=Thu Jul 13 05:31:00 CST 2017, time=2017-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=221232, encodeId=b23e2212327a, content=多运动运动, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Wed Jul 12 06:39:09 CST 2017, time=2017-07-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=221062, encodeId=a5c122106259, content=学了。。。。。。。。。。。。。, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4Neru1qt53a14aACuSzg3TZhkTcsPYVibyHibhTZ5L4k9qIBWiaej4lgomIsGptf8N16E4mTuIq2DVdJXjPjmwZKrLib/0, createdBy=5a0f2055853, createdName=135****7952平儿, createdTime=Tue Jul 11 14:37:24 CST 2017, time=2017-07-11, status=1, ipAttribution=)]
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    2017-07-12 天地飞扬

    多运动运动

    0

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    2017-07-11 135****7952平儿

    学了。。。。。。。。。。。。。

    0

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