Hypertension:多囊卵巢综合症患者更易出现未诊断高血压

2013-12-16 高晓方 译 医学论坛网

西班牙一项研究表明,在超重的多囊卵巢综合症(PCOS)女性患者中,未诊断高血压更为常见并可导致靶器官损伤。论文12月9日在线发表于《高血压》(Hypertension)。 此项横断面病例对照研究共纳入63例绝经后典型PCOS女性患者、33例月经正常非雄激素过多女性以及25例青年男性。消瘦和超重(BMI≥25 kg/m2)受试者分别为49和72例。受试者均无高血压病史,并且均是非吸烟者。评

西班牙一项研究表明,在超重的多囊卵巢综合症(PCOS)女性患者中,未诊断高血压更为常见并可导致靶器官损伤。论文12月9日在线发表于《高血压》(Hypertension)。

此项横断面病例对照研究共纳入63例绝经后典型PCOS女性患者、33例月经正常非雄激素过多女性以及25例青年男性。消瘦和超重(BMI≥25 kg/m2)受试者分别为49和72例。受试者均无高血压病史,并且均是非吸烟者。评估肥胖和雄激素过多对PCOS患者血压和超声心动图指标的影响。

结果显示,男性受试者的血压最高,对照女性最低,PCOS女性患者则处于中间水平。无论性别如何以及是否存在雄激素增多,在超重受试者中未诊断高血压均更为常见。超重PCOS患者的既往未诊断高血压发生率与超重男性相似,但高于对照女性。在男性以及PCOS女性患者中,高血压均可使左心室壁厚度增加。

原文出处:

Luque-Ramírez M, Martí D, Fernández-Durán E, Alpañés M, Alvarez-Blasco F, Escobar-Morreale HF.Office Blood Pressure, Ambulatory Blood Pressure Monitoring, and Echocardiographic Abnormalities in Women With Polycystic Ovary Syndrome: Role of Obesity and Androgen Excess.Hypertension. 2013 Dec 9.

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