郑州学者称,搭桥术前用硝酸酯类药物或增加输血风险

2019-02-19 xujing 中国循环杂志

郑州人民医院学者发现,术前静脉应用硝酸酯类药物或儿茶酚胺类药物是非体外循环冠状动脉搭桥术围术期红细胞输血危险因素。

郑州人民医院学者发现,术前静脉应用硝酸酯类药物或儿茶酚胺类药物是非体外循环冠状动脉搭桥术围术期红细胞输血危险因素。

研究纳入1 257 例单纯 OPCAB 患者,有603例(47.97%)患者输血,其中少量输血(≤ 4 U)471 例,大量输血(>4 U)132 例(占10.50%)。

输血定义:术中或术后 7-12 天内输注红细胞,输血量定义:术中和术后7-12 天内输注红细胞总数量。

红细胞输血标准:(1)术中 Hb ≤ 6.0 g/dl;(2)术后 Hb ≤ 8.0 g/dl;(3) 危重、高龄患者或怀疑或确定有活动性出血时 Hb ≤ 9.0 g/dl。

与少量输血者相比,大量输血者的年龄偏大、BMI 偏低、术前静脉应用儿茶酚胺类药物和硝酸酯类药物比例偏高。

研究亦表明,年龄偏大、BMI 偏低患者较年龄偏小、BMI 偏高患者,其输血风险高,且年龄越大、BMI 越低的患者,大量输血的风险越高。

研究的特有发现是:术前静脉应用硝酸酯类药物或儿茶酚胺类药物是搭桥手术患者输血的危险因素,并且与大量输血独立相关。

研究者建议,对于术前心功能较差的患者尽最大可能改善其心脏状态,增加手术耐受力,可降低输血风险,并减少输血量。

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    2019-09-01 zgwhgch
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    2019-02-20 windight
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    2019-02-20 zzc2214
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    2019-02-20 183****7028

    学习

    0

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    2019-02-19 一天没事干

    很好的学习机会

    0

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    2019-02-19 龙胆草

    学习谢谢分享

    0

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    2019-02-19 SCI我的梦

    谢谢分享

    0

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心脏搭桥术(图)

中国循环杂志:这些高危患者搭桥术前或需应用IABP

对于手术危险较高的搭桥患者,围手术期常需主动脉内球囊反博(IABP)进行辅助支持。近期阜外医院王现强、王巍、王跃堂等进行的研究显示,对于高危搭桥患者,术前置入IABP优化短期预后,而再次置入IABP是短期死亡的危险因素。 其中高危冠心病的诊断标准为:(1)≥3支冠脉显著狭窄;(2)冠脉左主干显著狭窄;(3)LVEF<0.4,或NYHA分级III 级或者IV 级;(4)急性心肌梗死或者药物