Rhinology:在非过敏性鼻炎中,干冷空气激发是一种可靠的诊断工具

2019-01-21 AlexYang MedSci原创

对非过敏性鼻炎(NAR)来说,还没有标准的诊断流程。非特异性鼻过敏反应(NHR)可以通过干冷空气(CDA)激发来进行有效的评估,同时也是NAR的一个必要特性。因此,最近,有研究人员评估了CDA激发在区分NAR患者中的诊断价值。研究人员在13名健康志愿者和15名NAR患者中对CDA激发进行了评估。研究发现,与健康志愿者相比,NAR患者在CDA激发后表现出了显著更大的变化,包括总鼻症状得分(TNSS)

对非过敏性鼻炎(NAR)来说,还没有标准的诊断流程。非特异性鼻过敏反应(NHR)可以通过干冷空气(CDA)激发来进行有效的评估,同时也是NAR的一个必要特性。因此,最近,有研究人员评估了CDA激发在区分NAR患者中的诊断价值。

研究人员在13名健康志愿者和15名NAR患者中对CDA激发进行了评估。研究发现,与健康志愿者相比,NAR患者在CDA激发后表现出了显著更大的变化,包括总鼻症状得分(TNSS)和鼻塞得分,然而,鼻溢液得分的变化相当。相似地,研究人员在2组之间观察到了鼻腔最小截面积(MCA)和总鼻体积(TNA)显著的差异。研究人员还建立了一个NAR的预测模型,Y =-3.285加上TNR(%)差异的2.520倍,加上TNSS差异的1.027倍,减去TNV(%)差异的6.542倍,曲线下面积为0.93。 另外,根据Youden指数,当其敏感性和特异性分别为93.3%和84.6%时,标准设定Y值大于-0.52。

最后,研究人员指出,在患者友好、安全和有效的要求下,研究人员基于CDA激发,通过主观评分和客观测试,成功的在中国人群中进行了首次NAR预测模型构建。

原始出处:

Huang Y, Lou H, Wang C et al. Cold dry air provocation is a reliable diagnostic tool in nonallergic rhinitis. Rhinology. 5 Jan 2019.

本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (5)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=2047066, encodeId=9209204e066a8, content=<a href='/topic/show?id=6f5294036b1' target=_blank style='color:#2F92EE;'>#过敏性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94036, encryptionId=6f5294036b1, topicName=过敏性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a8e213, createdName=hongbochen, createdTime=Fri Jul 26 11:02:00 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1723634, encodeId=defc1e236348d, content=<a href='/topic/show?id=7b08915917b' target=_blank style='color:#2F92EE;'>#诊断工具#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91591, encryptionId=7b08915917b, topicName=诊断工具)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c37033510464, createdName=surilei, createdTime=Sun Mar 31 13:02:00 CST 2019, time=2019-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1955712, encodeId=2c8a1955e128d, content=<a href='/topic/show?id=4f6599e04e9' target=_blank style='color:#2F92EE;'>#非过敏性鼻炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99704, encryptionId=4f6599e04e9, topicName=非过敏性鼻炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2c31495, createdName=liuyg0228, createdTime=Wed Apr 10 22:02:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358810, encodeId=62a53588109a, content=好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Mon Jan 21 14:54:00 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358805, encodeId=23f335880509, content=学习了,涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Mon Jan 21 13:31:14 CST 2019, time=2019-01-21, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=2047066, encodeId=9209204e066a8, content=<a href='/topic/show?id=6f5294036b1' target=_blank style='color:#2F92EE;'>#过敏性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94036, encryptionId=6f5294036b1, topicName=过敏性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a8e213, createdName=hongbochen, createdTime=Fri Jul 26 11:02:00 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1723634, encodeId=defc1e236348d, content=<a href='/topic/show?id=7b08915917b' target=_blank style='color:#2F92EE;'>#诊断工具#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91591, encryptionId=7b08915917b, topicName=诊断工具)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c37033510464, createdName=surilei, createdTime=Sun Mar 31 13:02:00 CST 2019, time=2019-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1955712, encodeId=2c8a1955e128d, content=<a href='/topic/show?id=4f6599e04e9' target=_blank style='color:#2F92EE;'>#非过敏性鼻炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99704, encryptionId=4f6599e04e9, topicName=非过敏性鼻炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2c31495, createdName=liuyg0228, createdTime=Wed Apr 10 22:02:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358810, encodeId=62a53588109a, content=好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Mon Jan 21 14:54:00 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358805, encodeId=23f335880509, content=学习了,涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Mon Jan 21 13:31:14 CST 2019, time=2019-01-21, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=2047066, encodeId=9209204e066a8, content=<a href='/topic/show?id=6f5294036b1' target=_blank style='color:#2F92EE;'>#过敏性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94036, encryptionId=6f5294036b1, topicName=过敏性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a8e213, createdName=hongbochen, createdTime=Fri Jul 26 11:02:00 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1723634, encodeId=defc1e236348d, content=<a href='/topic/show?id=7b08915917b' target=_blank style='color:#2F92EE;'>#诊断工具#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91591, encryptionId=7b08915917b, topicName=诊断工具)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c37033510464, createdName=surilei, createdTime=Sun Mar 31 13:02:00 CST 2019, time=2019-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1955712, encodeId=2c8a1955e128d, content=<a href='/topic/show?id=4f6599e04e9' target=_blank style='color:#2F92EE;'>#非过敏性鼻炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99704, encryptionId=4f6599e04e9, topicName=非过敏性鼻炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2c31495, createdName=liuyg0228, createdTime=Wed Apr 10 22:02:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358810, encodeId=62a53588109a, content=好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Mon Jan 21 14:54:00 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358805, encodeId=23f335880509, content=学习了,涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Mon Jan 21 13:31:14 CST 2019, time=2019-01-21, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=2047066, encodeId=9209204e066a8, content=<a href='/topic/show?id=6f5294036b1' target=_blank style='color:#2F92EE;'>#过敏性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94036, encryptionId=6f5294036b1, topicName=过敏性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a8e213, createdName=hongbochen, createdTime=Fri Jul 26 11:02:00 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1723634, encodeId=defc1e236348d, content=<a href='/topic/show?id=7b08915917b' target=_blank style='color:#2F92EE;'>#诊断工具#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91591, encryptionId=7b08915917b, topicName=诊断工具)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c37033510464, createdName=surilei, createdTime=Sun Mar 31 13:02:00 CST 2019, time=2019-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1955712, encodeId=2c8a1955e128d, content=<a href='/topic/show?id=4f6599e04e9' target=_blank style='color:#2F92EE;'>#非过敏性鼻炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99704, encryptionId=4f6599e04e9, topicName=非过敏性鼻炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2c31495, createdName=liuyg0228, createdTime=Wed Apr 10 22:02:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358810, encodeId=62a53588109a, content=好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Mon Jan 21 14:54:00 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358805, encodeId=23f335880509, content=学习了,涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Mon Jan 21 13:31:14 CST 2019, time=2019-01-21, status=1, ipAttribution=)]
    2019-01-21 lietome2

    好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=2047066, encodeId=9209204e066a8, content=<a href='/topic/show?id=6f5294036b1' target=_blank style='color:#2F92EE;'>#过敏性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=94036, encryptionId=6f5294036b1, topicName=过敏性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0a8e213, createdName=hongbochen, createdTime=Fri Jul 26 11:02:00 CST 2019, time=2019-07-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1723634, encodeId=defc1e236348d, content=<a href='/topic/show?id=7b08915917b' target=_blank style='color:#2F92EE;'>#诊断工具#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91591, encryptionId=7b08915917b, topicName=诊断工具)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c37033510464, createdName=surilei, createdTime=Sun Mar 31 13:02:00 CST 2019, time=2019-03-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1955712, encodeId=2c8a1955e128d, content=<a href='/topic/show?id=4f6599e04e9' target=_blank style='color:#2F92EE;'>#非过敏性鼻炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=99704, encryptionId=4f6599e04e9, topicName=非过敏性鼻炎)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=2c31495, createdName=liuyg0228, createdTime=Wed Apr 10 22:02:00 CST 2019, time=2019-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358810, encodeId=62a53588109a, content=好文,值得点赞!认真学习了,把经验应用于实践,为患者解除病痛。, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRuUXgacXpPeW0x8Z3Qr9c3I2kTic4ZIpR29iaftYgkjRcbv982icYMtqANBPYBgPnOia6mVtX76qMXuc/0, createdBy=d85d1636106, createdName=lietome2, createdTime=Mon Jan 21 14:54:00 CST 2019, time=2019-01-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=358805, encodeId=23f335880509, content=学习了,涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLDM9swhbgTo7nzqRKzMmzckmEoeTyLQVDCgjqsicjyhxPs0vPoYU6GsSYbCjSkNHicJkz3NL0a0EbUMVdNjkctXI6FocpGKaVr9E/0, createdBy=29392048316, createdName=王秀, createdTime=Mon Jan 21 13:31:14 CST 2019, time=2019-01-21, status=1, ipAttribution=)]
    2019-01-21 王秀

    学习了,涨知识了!

    0

相关资讯

Allergy:非过敏性鼻炎对病人生活品质影响的分析

不同于过敏性鼻炎(AR)对生活品质(QoL),非过敏性鼻炎对生活品质影响的程度在很长一段时间都处于未知状态,原因是缺乏评估NAR病人群体生活质量公认的调查问卷。最近,有研究人员进行了在NAR病人中的确定的微型-RQLQ调查问卷,随后对NAR病人的生活品质和AR病人和健康对照的生活品质进行了比较。其次,研究人员还在AR和NAR病人中评估了医药的使用和治疗的满意度。研究是一个观察性的群体研究,包括了2

Otolaryngol Head Neck Surg:非过敏性鼻炎患者与嗜酸性粒细胞联系和鼻激发测试后响应分析

最近,有研究人员评估了鼻嗜酸性粒细胞与鼻对过敏原提取物高反应性的关系。研究是一个回顾性的图表总结研究。研究包括了194名患有鼻炎症状(76名男性和118名女性),年龄在11-69岁之间,并进行了过敏测试。 研究人员根据研究结果,将参与者分成了4组:组A(过敏性鼻炎且嗜酸性粒细胞过多,n=26);组B(过敏性鼻炎且不患有嗜酸性粒细胞过多,n=77);组C(非过敏性鼻炎且嗜酸性粒细胞过多,n=20);