Radiology:深度学习在冠状动脉CTA钙化评分的应用

2022-01-15 shaosai MedSci原创

冠状动脉钙化评分(CAC)是一种有效的冠状动脉疾病风险分层的影像学指标。在临床上存在多种类型的钙化评分,其中Agatston钙化评分是使用最为广泛的一项。

 冠状动脉钙评分(CAC)是一种有效的冠状动脉疾病风险分层的影像学指标在临床上存在多种类型的钙评分,其中Agatston钙评分是使用最为广泛的一项。冠状动脉内的体素如果衰减超过预定的阈值130H以上,就被定义为钙。然后通过一个预定义的方程式来计算得分。过去采用的是半自动的方法进行计算近几年,人们尝试在平扫CT中自动计算Agatston评分,其中就包括基于深度学习的计算方法。

光谱CT利用了X射线光子衰减的能量依赖性,根据多能级下的材料分解提供更详细的组织分析。通过使用材料分解的虚拟碘减法算法,光谱CT扫描仪能够生成虚拟非强化(VNC)CT扫描。同时,在不需要额外辐射的情况下,成像后的重建可以取代真正的平扫CT。

近日,发表在Radiology杂志的一项研究提出了一种深度学习方法来自动量化CTA的钙化评分为快速准确的获得钙化评分提供了技术支持

 (A-F)钙化(蓝色箭头)在两位患者CT血管造影(CTA)、VNC CT和平扫CT扫描中的显示。VNC CT扫描(B,E)和平扫CT扫描(C,F)上的钙化外观相似,使用预定义的阈值130HU可以很容易获得,因为冠状动脉的衰减(B,C,E和F中的橙色箭头)明显小于130HU。然而,通过CTA(A,D)获得冠状动脉钙化(CAC)区域并估计相应的CAC评分可能具有挑战性,因为造影剂增强的动脉衰减不一。

总之,本研究提出了一种深度学习方法来自动量化来自CT血管造影(CTA)图像的冠状动脉钙(CAC)评分。本研究结果表明,所提出的方法可以准确地量化CAC,对CTA的风险进行分类。

原文出处

Dan Mu,Junjie Bai,Wenping Chen,et al.Calcium Scoring at Coronary CT Angiography Using Deep Learning.DOI:10.1148/radiol.2021211483

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    2022-04-19 zhouqu_8
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    2022-01-19 ms6000000656440728

    不错哦

    0

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    2022-01-15 小蚂蚁uu

    钙化积分,cta更加准确

    0

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    2022-01-15 qingbao2004

    学习了

    0

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    2022-01-15 ms2000000791187735

    学习

    0

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Circulation:普通人群亚临床动脉粥样硬化的发生率

CCTA 检查到的动脉粥样硬化的发生率随着 CAC 评分的增加而增加,即使 CAC 评分为 0 的个体,也有 5.5% 的存在动脉粥样硬化,0.4% 的存在明显狭窄

Hypertension:冠状动脉钙化评分用于个性化降压治疗指导

在当前指南不推荐治疗的人群中,利用CAC评分可指导高血压治疗和个体化降低心血管风险的预防策略。

JAHA:咖啡摄入量和冠状动脉钙化评分!

每天习惯性地摄入咖啡超过3杯降低了从不吸烟者亚临床动脉粥样硬化的几率。饮用咖啡对冠状动脉钙化有潜在的保护作用,特别是不吸烟者。

Int J Cardiol:冠状动脉钙化评分对有症状个体的预后价值

由此可见,这项荟萃分析表明CAC水平升高与稳定的、有症状的疑似CAD患者的MACE风险增加强烈且独立相关,CAC评分越高,风险越大。应用CAC扫描作为预测方法对于相当多的此类患者可能是有用的。

Circulation:低衰减斑块负荷——心肌梗死风险的强大预测指标!??

心肌梗死的未来风险通常通过心血管风险评分、冠状动脉钙评分或冠状动脉狭窄严重程度来评估。Williams等评估了冠状动脉CT血管造影(CCTA)中未钙化的低衰减斑块负荷是否可能更好地预测心肌梗死的未来风

Radiology:冠状动脉钙化评分在预测主动脉瓣置换术后患者预后中的价值

钙化性主动脉瓣狭窄是最常见的瓣膜性心脏病之一,未经治疗的中度或重度主动脉瓣狭窄患者的5年死亡率高于50%。