Sci Rep:商业化阴道产品对尿路致病菌和阴道共生菌的影响

2020-05-27 AlexYang MedSci原创

一半的绝经后女性会发生更年期泌尿生殖系统综合征,因此许多女性会使用润滑阴道的产品。阴道产品对尿道致病菌和阴道共生菌的影响还不清楚。

一半的绝经后女性会发生更年期泌尿生殖系统综合征,因此许多女性会使用润滑阴道的产品。阴道产品对尿道致病菌和阴道共生菌的影响还不清楚。

最近,有研究人员评估了5种阴道产品(KY Jelly、Replens Silky Smooth lubricant、coconut oil、Replens Long-Lasting moisturizer 和Trimo-San)对大肠杆菌和卷曲乳杆菌生长和生存能力的影响。细菌是共培养产物,同时包括了阴道上皮细胞和选择的阴道用产品。研究人员使用未配对t检验或者ANOVA对细菌的生长进行了比较。研究发现,除了coconut oil之外,其他所有产品均能显著的抑制实验室株系和临床株系大肠杆菌的生长(p<0.02)。只有2种产品(Replens Long-Lasting moisturizer 和Trimo-San)能够显著的抑制卷曲乳杆菌的生长(p<0.01),而Replens Silky Smooth却能够刺激其生长(p<0.01)。阴道上皮细胞和选择的阴道产品能够消除产品对大肠杆菌的抑制作用。

最后,研究人员指出,阴道保湿和润滑产品的使用能够抑制大肠杆菌的生长,且该效应能够被阴道上皮细胞减弱。卷曲乳杆菌生长抑制反应要比大肠杆菌小。

原始出处:

Kristin J. Hung, Patricia L. Hudson, Agnes Bergerat et al. Effect of commercial vaginal products on the growth of uropathogenic and commensal vaginal bacteria. Sci Rep. 06 May 2020

 

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1771812, encodeId=baa71e71812b0, content=<a href='/topic/show?id=62754005931' target=_blank style='color:#2F92EE;'>#商业#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40059, encryptionId=62754005931, topicName=商业)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Mon Jul 27 20:04:36 CST 2020, time=2020-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944077, encodeId=058919440e7fd, content=<a href='/topic/show?id=02c930028f2' target=_blank style='color:#2F92EE;'>#共生菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30028, encryptionId=02c930028f2, topicName=共生菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9ed371, createdName=楚秀娟, createdTime=Mon Jan 25 11:04:36 CST 2021, time=2021-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506766, encodeId=fec51506e667d, content=<a href='/topic/show?id=afce40064d1' target=_blank style='color:#2F92EE;'>#商业化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40064, encryptionId=afce40064d1, topicName=商业化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b549798360, createdName=yeaweam, createdTime=Fri May 29 04:04:36 CST 2020, time=2020-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626225, encodeId=f4a9162622564, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Fri May 29 04:04:36 CST 2020, time=2020-05-29, status=1, ipAttribution=)]
  2. [GetPortalCommentsPageByObjectIdResponse(id=1771812, encodeId=baa71e71812b0, content=<a href='/topic/show?id=62754005931' target=_blank style='color:#2F92EE;'>#商业#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40059, encryptionId=62754005931, topicName=商业)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Mon Jul 27 20:04:36 CST 2020, time=2020-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944077, encodeId=058919440e7fd, content=<a href='/topic/show?id=02c930028f2' target=_blank style='color:#2F92EE;'>#共生菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30028, encryptionId=02c930028f2, topicName=共生菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9ed371, createdName=楚秀娟, createdTime=Mon Jan 25 11:04:36 CST 2021, time=2021-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506766, encodeId=fec51506e667d, content=<a href='/topic/show?id=afce40064d1' target=_blank style='color:#2F92EE;'>#商业化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40064, encryptionId=afce40064d1, topicName=商业化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b549798360, createdName=yeaweam, createdTime=Fri May 29 04:04:36 CST 2020, time=2020-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626225, encodeId=f4a9162622564, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Fri May 29 04:04:36 CST 2020, time=2020-05-29, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1771812, encodeId=baa71e71812b0, content=<a href='/topic/show?id=62754005931' target=_blank style='color:#2F92EE;'>#商业#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40059, encryptionId=62754005931, topicName=商业)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Mon Jul 27 20:04:36 CST 2020, time=2020-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944077, encodeId=058919440e7fd, content=<a href='/topic/show?id=02c930028f2' target=_blank style='color:#2F92EE;'>#共生菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30028, encryptionId=02c930028f2, topicName=共生菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9ed371, createdName=楚秀娟, createdTime=Mon Jan 25 11:04:36 CST 2021, time=2021-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506766, encodeId=fec51506e667d, content=<a href='/topic/show?id=afce40064d1' target=_blank style='color:#2F92EE;'>#商业化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40064, encryptionId=afce40064d1, topicName=商业化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b549798360, createdName=yeaweam, createdTime=Fri May 29 04:04:36 CST 2020, time=2020-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626225, encodeId=f4a9162622564, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Fri May 29 04:04:36 CST 2020, time=2020-05-29, status=1, ipAttribution=)]
    2020-05-29 yeaweam
  4. [GetPortalCommentsPageByObjectIdResponse(id=1771812, encodeId=baa71e71812b0, content=<a href='/topic/show?id=62754005931' target=_blank style='color:#2F92EE;'>#商业#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40059, encryptionId=62754005931, topicName=商业)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=仁心济世, createdTime=Mon Jul 27 20:04:36 CST 2020, time=2020-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1944077, encodeId=058919440e7fd, content=<a href='/topic/show?id=02c930028f2' target=_blank style='color:#2F92EE;'>#共生菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=30028, encryptionId=02c930028f2, topicName=共生菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e9ed371, createdName=楚秀娟, createdTime=Mon Jan 25 11:04:36 CST 2021, time=2021-01-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1506766, encodeId=fec51506e667d, content=<a href='/topic/show?id=afce40064d1' target=_blank style='color:#2F92EE;'>#商业化#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=40064, encryptionId=afce40064d1, topicName=商业化)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8b549798360, createdName=yeaweam, createdTime=Fri May 29 04:04:36 CST 2020, time=2020-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1626225, encodeId=f4a9162622564, content=<a href='/topic/show?id=c11d864884d' target=_blank style='color:#2F92EE;'>#致病菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86488, encryptionId=c11d864884d, topicName=致病菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=395f25, createdName=爆笑小医, createdTime=Fri May 29 04:04:36 CST 2020, time=2020-05-29, status=1, ipAttribution=)]

相关资讯

Sci Transl Med:细菌抗原引发自身免疫性疾病

狼疮(Lupus)是一种自身免疫性疾病,患者在发病过程中会对很多自身抗原产生抗体。而最早出现的自身抗体中常见的靶点是名为Ro60的RNA结合蛋白。

Nat Immunol: 肠道菌与宿主的相爱相杀

提到肠道菌群,即使是非专业人士也肯定不会陌生。近年来,健康产业热炒的肠道有益菌群概念已经让众多保健品厂家赚的盆满钵满了。然而,时至今日对于肠道共生菌的相关机制仍然是个迷。诸多研究表明人是由人体与共生菌共同组成的超级生物体,并且肠道共生菌在人体健康中发挥重要作用。有意思的是,很多研究暗示了肠道共生菌“无所不能”并“无恶不作”。肠道共生菌如何发挥这些复杂作用目前所知甚少。对这些机制的探索恰恰是揭示

Cell Host & Microbe:毛囊滋养的不只是发根,更能调节免疫系统

Ccl20- Ccr6信号通路是诱导T细胞迁移到皮肤,并在毛囊与细菌接触,从而吸引更多的T细胞迁移,并且产生Treg细胞的重要机制

Sci Rep:一个前列腺来源的共生表皮葡萄球菌菌株能够预防和减轻UPEC感染诱导的慢性前列腺炎

慢性前列腺炎/慢性盆腔疼痛综合症(CP/CPPS)是一种常见的综合症,并且治疗方法有限且发病原因未知。之前,有研究人员确定了疾病起始中病理感染的一个潜在角色。即从CP/CPPS患者中分离的尿路致病性大肠杆菌菌株CP1的尿道内感染能够诱导小鼠前列腺炎和触觉异常性疼痛。研究人员同样阐释了一个从健康个体分离的前列腺特异性表皮葡萄球菌NPI(非疼痛诱导)在小鼠模型中能够减少疼痛和炎症。最近,有研究人员关注