Int J Pediatr Otorhinolaryngol:过敏性鼻炎儿童患者呼出一氧化氮水平比较研究

2019-08-16 AlexYang MedSci原创

最近,有研究人员确定了是否测量呼出一氧化氮(eNO)水平能够帮助区分过敏性鼻炎(AR)儿童和健康对照,并探究了是否AR与疾病严重度相关。研究包括了5-15岁的儿童,并分成了过敏性鼻炎组(n=40)和健康对照组(n=40)。研究进行的时间为2015年8月到2016年。研究人员根据ARIA分类将eNO水平与患者的临床疾病严重度进行了比较。研究发现,AR儿童中eNO水平(12.64±14.67ppb)要

最近,有研究人员确定了是否测量呼出一氧化氮(eNO)水平能够帮助区分过敏性鼻炎(AR)儿童和健康对照,并探究了是否AR与疾病严重度相关。

研究包括了5-15岁的儿童,并分成了过敏性鼻炎组(n=40)和健康对照组(n=40)。研究进行的时间为2015年8月到2016年。研究人员根据ARIA分类将eNO水平与患者的临床疾病严重度进行了比较。研究发现,AR儿童中eNO水平(12.64±14.67ppb)要比健康对照组(7.00±6.33ppb)显著更高(p=0.046)。在永久性AR组(17.11±18.40ppb),eNO水平要比间歇性AR组(8.59±8.88ppb, p=0.024)和健康对照组(7.00±6.33ppb, p=0.008)显著更高。在患有AR的儿童中,eNO与性别、年龄、体重和被动吸烟暴露的关系无显著差异。

最后,研究人员指出,呼出一氧化氮水平在不具有并发性哮喘的AR儿童中提高。他们的结果表明了一氧化氮参数可能在监测骨过敏性鼻炎严重度和检测治疗效果中具有意义。另外,医生在以呼出一氧化氮作为监测参数来治疗哮喘时,应该考虑AR并发症的可能。

原始出处:

Sapsaprang S, Tanticharoenwiwat P, Kulalert P et al. Comparison of exhaled nitric oxide levels in pediatric patients with allergic rhinitis. Int J Pediatr Otorhinolaryngol. 26 Jul 2019

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    2020-04-09 feather89
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    2019-08-18 txqjm

    谢谢了,学习

    0

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    2019-08-16 329523732

    不错

    0

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