JAMA Netw open:近54万国人研究!男士抑郁,因心血管病过早死亡风险增49%!

2020-02-18 朱朱 中国循环杂志

近期,JAMA网络开放子刊发表的一项覆盖近54万成年人(中国慢性病前瞻性研究51.3万+东风-同济研究2.6万)的中国队列研究提示,抑郁是全因死亡和心血管死亡的危险因素之一。

近期,JAMA网络开放子刊发表的一项覆盖近54万成年人(中国慢性病前瞻性研究51.3万+东风-同济研究2.6万)的中国队列研究提示,抑郁是全因死亡和心血管死亡的危险因素之一。

校正社会人口学因素、生活方式因素和健康状态等的多因素分析显示,上述两队列中,抑郁者全因死亡风险分别增加32%和17%,心血管死亡风险分别增加22%和32%。

研究者指出,抑郁的男士风险尤其高,上述两队列中,全因死亡风险分别增加53%和24%,心血管死亡风险分别增加39%和49%。

但在抑郁的女士中,仅中国慢性病前瞻性研究显示全因死亡风险增加19%。

研究者指出,中国抑郁症和心血管病相关疾病负担均较重,而治疗率较低,因此,中国亟需加强对抑郁患者的管理,作为预防早死的措施之一。

临床医生尤其要注意抑郁症患者的心血管危险因素,如果患者是心血管疾病或死亡高危人群,那么要积极给予预防或治疗措施来降低风险。

中国慢性病前瞻性队列纳入512 712人,其平均年龄为52岁,严重抑郁发作的12个月患病率为0.64%。

东风-同济队列纳入26 298人,其平均年龄为63.6岁,该队列中有临床意义的抑郁症状1个月患病率为17.96%。
Association of Depression With All-Cause and CVD Mortality Stratified by Age

中国慢性病前瞻性研究采用世界卫生组织简版复合性国际诊断访谈表来诊断抑郁,东风-同济研究采用的诊断方法是从该表改良而来的一个7项症状调查问卷。

原始出处:Ruiwei Meng, PhD; Canqing Yu, PhD; Na Liu, PhD; et al. Association of Depression With All-Cause and Cardiovascular Disease Mortality Among Adults in China. JAMA Netw Open, 2020, 3(2): e1921043.

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    2020-11-24 feather89
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    2020-02-18 canlab
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    2020-02-27 14737642m56(暂无昵称)

    有没有文章关注过医护人员抑郁与心血管疾病?

    0

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    2020-02-18 旺医

    顶刊就是顶刊,谢谢梅斯带来这么高水平的研究报道,我们科里同事经常看梅斯,分享梅斯上的信息

    0

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