Behavioural Brain Research:α和β带神经振荡失步预测正常衰老中的语音和肢体运动反应

2020-07-22 MedSci原创 MedSci原创

正常的老化与运动计时机制的下降有关,这与运动的计划和执行有关。

目前尚不清楚正常的衰老如何影响老年人群运动的潜在神经机制。作何本研究中,记录了两组年轻人和老年人的脑电活动,而他们则根据时间可预测和不可预测的感觉刺激执行了随机的语音和肢体运动反应时间任务。

方法:在语音产生和肢体运动期间,老年人比年轻人的速度明显慢,尤其是在对时间不可预测的感觉刺激做出反应时。这种行为效应伴随着老年人(与年轻成年人相比)的α(7-12 Hz)和β(13-25 Hz)带神经振荡活动失步,主要在言语产生和肢体反应的预备运动前阶段运动。此外,我们发现,较年轻的成年人较快的运动反应时间与较弱的运动前前α和β带神经活动失步密切相关,而与刺激时机和反应方式无关。然而,α和β活动的运动前成分在老年人中是特定于时间的,并且响应于时间可预测的感觉刺激而更强烈地失步。

结果:突出了α和β带神经振荡在运动定时处理机制中的作用,并反映了正常衰老过程中语音产生和肢体运动的计划阶段它们的功能缺陷。

原文出处:

Johari, K. and R. Behroozmand, Event-related desynchronization of alpha and beta band neural oscillations predicts speech and limb motor timing deficits in normal aging. Behavioural Brain Research, 2020. 393: p. 112763.

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    2020-07-30 gq1688888

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    2020-07-24 qjddjq
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    2020-07-24 yangshch
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    2020-07-23 老婆子

    学习了

    0

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    2020-07-23 ms5000001953269209

    学习

    0

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    2020-07-23 linyidao

    中国人口老年化

    0

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老龄化表型,如健康寿命(healthspan)、总寿命(lifespan)和长寿(longevity),是我们大家都感兴趣的,对此,我们需要特别大的样本量来进行遗传学研究。