Hypertension:PM1与儿童高血压

2019-12-16 xing.T MedSci原创

由此可见,这项研究首次提供了证据,表明长期暴露于PM1与儿童高血压有关,并且PM1可能是PM2.5导致高血压的主要因素。研究人员和政策制定者应更加关注PM1的潜在健康效应。

关于直径≤1μm(PM1)的空气传播颗粒和直径≤2.5μm(PM2.5)的空气传播颗粒与儿童血压(BP)之间存在关联的证据很少。近日,心血管权威杂志Hypertension上发表了一篇研究文章,为了解决这一研究空缺,研究人员进行了一项研究在中国儿童中探讨了这种关联。

在2012年至2013年期间,研究人员从中国东北7个城市的62所学校招募了9354名5至17岁的儿童。研究人员用水银血压计测量了他们的血压,并使用时空模型估算了参与者家庭住址的每日PM1和PM2.5环境暴露量。研究人员使用广义线性混合回归模型评估了颗粒物暴露与BP之间的关联。

研究结果表明,PM1暴露量每增加10 mg/m3 ,收缩压升高2.56mmHg(95%CI为1.47–3.65),高血压几率增加61%(比值比=1.61[95%CI为1.18-2.18])。在报道的PM2.5暴露与血压之间的关联中,PM1似乎起重要作用,研究人员发现空气中PM1/PM2.5比值(范围为0.80-0.96)与血压和高血压有关。年龄和体重改变了空气污染物与BP之间的关联(P<0.01),而在年龄较小(≤11岁)和超重/肥胖的儿童中关联更强。

由此可见,这项研究首次提供了证据,表明长期暴露于PM1与儿童高血压有关,并且PM1可能是PM2.5导致高血压的主要因素。研究人员和政策制定者应更加关注PM1的潜在健康效应。 

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    2020-06-27 医者仁心
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    2020-03-26 feather89
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  6. [GetPortalCommentsPageByObjectIdResponse(id=2018319, encodeId=a6442018319ea, content=<a href='/topic/show?id=4bfa2853506' target=_blank style='color:#2F92EE;'>#儿童高血压#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=28535, encryptionId=4bfa2853506, topicName=儿童高血压)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=263b421, createdName=zhaozuguo, createdTime=Sat Jun 13 08:29:00 CST 2020, time=2020-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974517, encodeId=f4a419e4517b4, content=<a href='/topic/show?id=e37b144015f' target=_blank style='color:#2F92EE;'>#PM1#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14401, encryptionId=e37b144015f, topicName=PM1)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Sat Jun 27 21:29:00 CST 2020, time=2020-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2039127, encodeId=ac69203912e7e, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Mon Jan 20 17:29:00 CST 2020, time=2020-01-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1728228, encodeId=2d4d1e2822805, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f06c33759375, createdName=feather89, createdTime=Thu Mar 26 10:29:00 CST 2020, time=2020-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1501420, encodeId=a834150142029, content=<a href='/topic/show?id=f2db9238f9' target=_blank style='color:#2F92EE;'>#Hypertension#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=9238, encryptionId=f2db9238f9, topicName=Hypertension)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=11ff9497046, createdName=jambiya, createdTime=Wed Dec 18 12:29:00 CST 2019, time=2019-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=377060, encodeId=a4e73e706046, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=77, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/08/03/0e492dda8bcc1f98474b74c2863aca87.jpg, createdBy=068d2446376, createdName=Dr Z, createdTime=Tue Dec 17 07:22:15 CST 2019, time=2019-12-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=377059, encodeId=e5173e70591b, content=谢谢了,学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=91, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Tue Dec 17 07:17:45 CST 2019, time=2019-12-17, status=1, ipAttribution=)]
    2019-12-17 Dr Z

    学习了

    0

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    2019-12-17 txqjm

    谢谢了,学习

    0

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