OGTT,你被它“忽悠”过吗?

2016-12-08 医学界内分泌频道 医学界内分泌频道

导语:看似简单的口服葡萄糖耐量试验,如果医生不将注意事项向受检查者交代清楚,那么即使是小小的散步,都会影响检查结果。口服葡萄糖耐量试验,简称OGTT,是一种葡萄糖负荷试验,用以了解胰岛β细胞功能和机体对血糖的调节能力,是临床常用的用于诊断糖尿病的确诊试验,具体过程是:75 g无水葡萄糖粉(或82.5 g含一分子结晶水的葡萄糖粉)溶于250~300 ml水中,于5分钟内喝完,从喝第一口开始计时,分别

导语:看似简单的口服葡萄糖耐量试验,如果医生不将注意事项向受检查者交代清楚,那么即使是小小的散步,都会影响检查结果。



口服葡萄糖耐量试验,简称OGTT,是一种葡萄糖负荷试验,用以了解胰岛β细胞功能和机体对血糖的调节能力,是临床常用的用于诊断糖尿病的确诊试验,具体过程是:75 g无水葡萄糖粉(或82.5 g含一分子结晶水的葡萄糖粉)溶于250~300 ml水中,于5分钟内喝完,从喝第一口开始计时,分别于0.5小时、1小时、2小时、3小时抽取肘静脉血检测血糖变化,观察病人耐受葡萄糖的能力。  

这个试验是目前公认的诊断糖尿病的金标准,虽然貌似稀松平常,但是如果有些细节没有做到位,很可能被试验结果“忽悠”了!  

最近遇到一位患者,男性,50岁,体检时发现空腹血糖升高,达6.8 mmol/L,于是做OGTT,以判断有无糖尿病。  

化验结果出来,完全正常。但患者的一句话提了个醒:“医生,原来一走路血糖就下来了!”原来他服完糖水,觉得时间难捱,便溜出去散步,到了抽血时间再回到医院。因为工作太忙,医护人员都忘了告诉患者,OGTT必须在安静状态下进行,而在活动状态下,服糖后的血糖可能会下降,试验结果可能出现假阴性!  

其实,OGTT“忽悠”人的地方还不只如此。试验前,有些患者为让血糖下降刻意减少主食量,或者还在口服避孕药、利尿剂和烟酸等药物,或者摄入过多脂肪,甚至头一晚还吃了夜宵,或者试验期间情绪激动,抑或伴有感冒发烧,在这些因素的作用下血糖都可能会进一步升高,容易出现假阳性的结果。  

为了不被OGTT“忽悠”,医生们必须将以下的一些注意点向进行检查的患者们交代清楚,做好充分准备:  

1、保证试验前3天有足量的碳水化合物的摄入,一般应大于250g/d,不能刻意节食,尤其是老年患者。  

2、饮食中脂肪含量过高或过低对检查也有明显影响,故必须同时注意脂肪摄入量标准化,即每日摄入鱼、肉、蛋、禽等动物性食物总计在150~200g,油脂摄入约25g。  

3、如果使用避孕药,应在试验前1周停用,试验前3~4天停用烟酸、利尿剂、口服降血糖药、水杨酸钠和普蔡洛尔等药物。  

4、如有发热、感染、手术等应激情况,此时不能作该检查。  

5、OGTT的前一天,应在晚上九点开始禁食,禁食时间至少8小时,可以饮水。当天的检查必须在早上7~9点进行。  

6、试验期间应注意避免精神刺激,禁止吸烟,不能活动,可坐或平卧,保持安静状态。  

医生们在判读OGTT结果时,应注意有无相关干扰因素。也可以把上述细节问题做成卡片,交给患者,以保证试验顺利进行。

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    2016-12-29 susice

    是的,我们平时都忽略了

    0

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    2016-12-26 1e1c7044m80(暂无匿称)

    细节真的很重要。

    0

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    2016-12-13 yfjms

    细心加耐心

    0

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    2016-12-12 1e1263e3m20(暂无匿称)

    细节决定判断,涨记性了

    0

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    2016-12-11 雅文博武

    学习了很多先进的医学知识讲座

    0

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    2016-12-10 186****0580(小山羊)

    学习了,知道了。

    0

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    2016-12-10 舒心和人

    感谢分享,小细节是要注意

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=166493, encodeId=48f516649346, content=是的,我们平时都忽略了, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Thu Dec 29 06:51:36 CST 2016, time=2016-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=165749, encodeId=6174165e495d, content=细节真的很重要。, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f97c2000394, createdName=1e1c7044m80(暂无匿称), createdTime=Mon Dec 26 09:43:44 CST 2016, time=2016-12-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162522, encodeId=c24716252292, content=细心加耐心, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Tue Dec 13 19:44:53 CST 2016, time=2016-12-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=162040, encodeId=d4c21620403d, content=细节决定判断,涨记性了, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84e21956153, createdName=1e1263e3m20(暂无匿称), createdTime=Mon Dec 12 00:05:20 CST 2016, time=2016-12-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161947, encodeId=cc2616194e2e, content=学习了很多先进的医学知识讲座, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161027/IMG58114E1818EA51495.jpg, createdBy=4b2c1959822, createdName=雅文博武, createdTime=Sun Dec 11 11:34:44 CST 2016, time=2016-12-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161743, encodeId=e34a161e439c, content=学习了,知道了。, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Sat Dec 10 16:29:05 CST 2016, time=2016-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161621, encodeId=34f11616210a, content=感谢分享,小细节是要注意, beContent=null, objectType=article, channel=null, level=null, likeNumber=20, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160907/IMG57D00CF1965701770.jpg, createdBy=565c1948251, createdName=舒心和人, createdTime=Sat Dec 10 08:17:46 CST 2016, time=2016-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161609, encodeId=64c31616096f, content=还真有很多点没认真处理,谢谢提醒!, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160916/IMG57DBEDBBA66BD2947.jpg, createdBy=3b181951777, createdName=ren1mw, createdTime=Sat Dec 10 07:52:48 CST 2016, time=2016-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1348527, encodeId=e7f1134852ec7, content=<a href='/topic/show?id=ee41132e8b1' target=_blank style='color:#2F92EE;'>#OGTT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13278, encryptionId=ee41132e8b1, topicName=OGTT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a9de34, createdName=shenxlcyp, createdTime=Sat Dec 10 06:39:00 CST 2016, time=2016-12-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=161528, encodeId=eda6161528bd, content=谢谢分享!!!!!!!, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Fri Dec 09 20:50:03 CST 2016, time=2016-12-09, status=1, ipAttribution=)]
    2016-12-10 ren1mw

    还真有很多点没认真处理,谢谢提醒!

    0

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    2016-12-10 shenxlcyp
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    2016-12-09 知难而进

    谢谢分享!!!!!!!

    0

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