基于多组学的肺小结节良恶性鉴别诊断前瞻性多中心临床研究:直播预告

2021-04-17 网络 网络

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肺癌的发病率和死亡率均处于我国恶性肿瘤首位。晚期肺癌患者的预后很差,而早期肺癌患者经过以手术为主的科学治疗预后良好。绝大多数早期肺癌表现为肺结节,因此,早期发现并识别出恶性肺结节患者,是降低肺癌死亡风险的重要预防措施。

据统计,中国人群中肺癌高危人群比例占整体人群比例 20% 以上,在肺癌高危人群中肺结节的发病率达到 35.5%,即超过1亿的中国人为肺结节患者。

肺部小结节 95% 以上都是良性结节。目前在进行小于 3cm 的肺小结节良恶性鉴别诊断时,对 LDCT 影像的临床判读经验要求较高,且缺乏形态影像信息以外的其他生物学信息补充。临床上亟需一套包含了影像和分子检测等多层次信息的肺小结节良恶性鉴别诊断解决方案。

MISSION( Multi-omIcs claSSIfier for pulmOnary Nodules ) 计划是由上海市肺科医院等全国十数家医院共同参与由泰莱生物牵头发起,旨在利用多组学技术(代谢组、蛋白组、表观遗传组、影像组),针对医学影像显示肺小结节(≤3cm)的患者进行肺小结节良恶性鉴别诊断的前瞻性多中心临床研究项目。

MISSION 计划将分 2 期进行,预计共计入组 2 万例临床样本,为目前国内最大的多组学单癌种的临床鉴别诊断前瞻性多中心临床研究队列。

MISSION・基于多组学的肺小结节良恶性鉴别诊断前瞻性多中心临床研究启动仪式将在本周日4月18日 下午15:30进行线上直播。启动仪式上,上海市肺科医院副院长陈昶教授将与大家进行该研究项目的具体分享。另外,武汉大学龚健雅院士、四川大学华西医院疾病分子网络前沿中心谢丹教授等嘉宾,也将就生命健康数据的人工智能研究、多组学技术研究等领域进行分享。

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    2021-12-11 gjsgj
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    2021-04-18 zhu333

    好期待

    0