2015年癌症检测前沿技术盘点

2015-12-29 佚名 生物360

每年,癌症在全球致死700万人,我国也有100万人因此失去生命。为了降伏这一绝症,科学家们付出了极大努力,研究出多种癌症检测技术。那么,2015年又有哪些令人瞩目的癌症检测技术呢? 1、新型成像检测技术 近日,刊登在国际杂志《CancerResearch》上的一项研究报告中显示,来自曼彻斯特大学等处的科学家通过研究开发了一种新型成像检测技术,其可以在肿瘤扩散之前帮助医生们鉴别出更多危险的肿

每年,癌症在全球致死700万人,我国也有100万人因此失去生命。为了降伏这一绝症,科学家们付出了极大努力,研究出多种癌症检测技术。那么,2015年又有哪些令人瞩目的癌症检测技术呢?

1、新型成像检测技术

近日,刊登在国际杂志《CancerResearch》上的一项研究报告中显示,来自曼彻斯特大学等处的科学家通过研究开发了一种新型成像检测技术,其可以在肿瘤扩散之前帮助医生们鉴别出更多危险的肿瘤,并且指导临床治疗。研究者利用一种新出现的名为氧增强的磁共振成像技术来通过将癌细胞植入小鼠机体中,从而绘制出缺氧性肿瘤的位置,该技术未来或可用于癌症病人的临床研究中。

未来,研究人员在此基础上也许会开发出更好的技术,为有效治疗癌症患者提供更多的希望。

2、血清胃功能检测技术

同济大学附属杨浦医院引进血清胃功能检测技术将用于早期胃癌筛查。在做这项筛查时,受检人只要抽2毫升的静脉血,通过检测就能“发现”胃黏膜病变风险。抽血检查微创、安全、经济、便捷,适用于大面积的人群普查,对于提高早期胃癌的诊治率很有意义。专家指出,早期胃癌患者大多都没有特殊的症状,做血清胃功能检查可助尽早发现潜在的风险。对于血清胃功能检查异常的患者再进一步进行精细胃镜检查,即对可疑部位进行放大内镜、染色内镜等更精细的检查,并进行病理检查,可以提高早期胃癌的检查率。

这意味着,更多胃癌患者可以获得早诊早治的机会。

3、人造钻石检测技术

澳大利亚研究人员日前利用人造钻石成功甄别出癌细胞,这或许将在检测早期癌症中发挥关键作用。据澳大利亚广播公司报道,悉尼大学研究人员发现,将用纳米技术合成的人造钻石磁化,本身不会发光的钻石会在核磁共振检测中发光。经磁化的钻石依附在检测癌细胞的化学物质上被注入体内,如果发现癌细胞,钻石会在核磁共振检测中发光。研究人员表示,这种技术的好处是不用开刀就能准确检测到癌细胞,他们希望以此检测出胰腺癌等初期难以被检测的癌症。研究负责人表示,他们使用的人造钻石成本相对低廉。这项检测技术有望在数年后进入临床试验阶段。

任何及早发现癌细胞的方法都是受欢迎的,这意味着能更有效地治疗癌症。

4、新型荧光寿命成像技术

过去,医生通常使用价值10万美元的设备来检测病人的癌症。但近期麻省理工学院的研究人员正在进行一种技术检测,一种被称为荧光寿命成像的技术,它只需花费100美元。该技术采用荧光寿命,即荧光发光时间技术,这些荧光能吸收光并在短时间内重新发出光。通过与特定化学物质反应作用,荧光的吸收和发射之间的时间间隔能通过一种可预测的方式干预改变。

100美元的产品显然降低了成本,而且实用的诊断技术将在发展国家中更快地普及。

5、针对血液和脑脊髓液样本的检测技术

剑桥大学的研究人员开发了一种针对血液和脑脊髓液样本的检测技术,主要基于样本中微型核糖核酸的情况来判读生殖细胞瘤的发展,因为通常在恶性生殖细胞瘤中,能够找到大量这种物质存在。研究人员说,这一新的检测技术能通过简单的步骤判断生殖细胞瘤是恶性还是良性,并且医生通过这项技术还能评估对肿瘤的治疗效果,加上这一检测技术非常安全、低成本因此可频繁使用,有助医生观察肿瘤是否出现复发情况。

这种新开发的无创、低成本检测技术能更好地帮助医生诊断恶性生殖细胞瘤,以便及时展开治疗,提高疗效。

6、核医学分子影像检查核医学与分子影像学

作为一个新兴学科,近年来取得了迅猛发展,在疾病的临床诊断、治疗和医学研究中发挥越来越重要的作用,尤其是在肿瘤的诊断和治疗中显得尤为突出。分子影像学就是利用现代医学影像技术(如PET、PET-CT、SPECT、SPECT甚至MRI等)观察特定分子探针在体内的分布进而对疾病进行诊断和研究的学科。能够在活体条件下、在分子水平上、无创伤的对疾病进行诊断和研究。其中PET-CT是最为杰出的代表。可以进行肿瘤的诊断和分期、监测肿瘤复发和转移、判定预后等等。

分子影像学是对癌症早期诊断和分期治疗更有价值的技术研究,既有效推进靶向性治疗,也能够节省癌症医疗费用的浪费。

7、活性硅芯片

美国哥伦比亚大学科学家近日研制出一种活性硅芯片,该芯片将成为微电子技术和生物系统一体化的过渡环节。专家指出,在数年后纳米技术发展所取得的突破可帮助确定人体内存在的癌细胞,此发明还将有助于监测环境中有毒物质。专家称,这种芯片不仅能收集能量,还能识别分子。对于这种芯片的用途可能会被继续挖掘出来。

在不久的将来,该芯片或将能使微电子技术植入活体细胞。

8、三维断层高速扫描技术

台湾大学今天发表“高速次微米三维断层扫描仪”技术,采用非侵入式,而且可以更快、观察到更小癌细胞,可用来检测皮肤癌、大肠癌、黄斑部病变等,协助早期诊断早期治疗,预计最快2017年初可以正式使用。以目前检测技术,恶性肿瘤要成长到1毫米才有机会检验出,但三维断层高速扫描仪以高亮度晶体光纤光源技术,透过光照透析皮肤表皮层,可直接、快速观察组织结构及血球细胞等活体动态影像,对比癌细胞与正常细胞差异,且可观测到0.01毫米,比现行技术解析度更高,成功监识率达近9成。

现在诊断癌症多半是观察结构和癌细胞,透过高速次微米三维断层扫描仪,可以更快速观察细胞,提早进行后续治疗,如果再结合内视镜检测,包括大肠癌等都可以早期检测。

9、尿液检测新技术

日本一个科研小组日前宣布成功研究出一种新型的癌症检测技术,检测只需提取被检者1滴尿液,即可利用体长大约1毫米的线虫来诊断被检者是否患有癌症。研究小组以218名健康人和24名癌症患者为对象进行了一项实验,实验提取了每位参与者的1滴尿液,然后将线虫放入尿液中,并观察线虫的移动情况。结果发现运用这项技术检测癌症的准确度高达95.8%。而通过血液对同一批患者进行癌症检测的准确度仅为16.2%至25%。

该科研小组称,将继续提高诊断精度,争取用10年左右的时间使这项技术投入实用。

10、新型胰腺癌检查仪

日本国立癌症研究中心团队开发出一款新型胰腺癌检查仪,该检查仪仅需检查人体血液成分就能准确检查出个体是否患有胰腺癌,准确率接近100%。据悉,该团队研究人员发现,人体患胰腺癌后,血液中一种名叫“apoA2同种型”的蛋白质浓度会下降,于是团队研究开发出了这种新型检查仪,通过测定血液中此蛋白质浓度诊断个体是否患有胰腺癌。据了解,团队还以癌症患者和正常人共计653人为对象,对检查仪进行了测试。测试结果显示,该检查仪能以97%到100%的该准确率从653名测试对象中,检查出胰腺癌早期患者。

胰腺癌是众多癌症中最难早期发现早期治疗的癌症之一,患胰腺癌5年后,患者的相对存活率不到10%。该团队表示,今后将于日本神户大学合作,将仪器的测试对象由653人扩大至5000人,进一步认证该仪器的准确性,并在3年后,在医疗领域大规模推广应用该新型胰腺癌检查仪。

未来几年,随着这些技术的不断涌现,它们可能为癌症治疗带来非常广阔的前景,提高每个癌症护理的质量和效率。相信在不久的将来,我们不再谈癌色变。

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    2015-12-30 sword20000

    越来越无创,越来越精准化。

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1765451, encodeId=151a1e654512a, content=<a href='/topic/show?id=dee3e139503' target=_blank style='color:#2F92EE;'>#癌症检测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71395, encryptionId=dee3e139503, topicName=癌症检测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Thu Feb 18 01:00:00 CST 2016, time=2016-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50371, encodeId=14ed503e1f9, content=越来越无创,越来越精准化。, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLAibgOibuZnfdFE64hJHibbD6WwEgyaXx7DtibMOSicJ6JZoLEAIdAdkhDmHWO7P7OXg2tkTicZy9libryicw/0, createdBy=aa991670466, createdName=sword20000, createdTime=Wed Dec 30 07:41:00 CST 2015, time=2015-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50346, encodeId=18ac5034640, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Tue Dec 29 21:49:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50334, encodeId=85c2503342f, content=good, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc9a1675161, createdName=樱桃树, createdTime=Tue Dec 29 20:48:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50302, encodeId=50d55030220, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:15:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50299, encodeId=426f502996c, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50300, encodeId=5ecc5030029, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50301, encodeId=e0e55030109, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=)]
    2015-12-29 dhzzm

    值得学习

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1765451, encodeId=151a1e654512a, content=<a href='/topic/show?id=dee3e139503' target=_blank style='color:#2F92EE;'>#癌症检测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71395, encryptionId=dee3e139503, topicName=癌症检测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Thu Feb 18 01:00:00 CST 2016, time=2016-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50371, encodeId=14ed503e1f9, content=越来越无创,越来越精准化。, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLAibgOibuZnfdFE64hJHibbD6WwEgyaXx7DtibMOSicJ6JZoLEAIdAdkhDmHWO7P7OXg2tkTicZy9libryicw/0, createdBy=aa991670466, createdName=sword20000, createdTime=Wed Dec 30 07:41:00 CST 2015, time=2015-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50346, encodeId=18ac5034640, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Tue Dec 29 21:49:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50334, encodeId=85c2503342f, content=good, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc9a1675161, createdName=樱桃树, createdTime=Tue Dec 29 20:48:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50302, encodeId=50d55030220, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:15:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50299, encodeId=426f502996c, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50300, encodeId=5ecc5030029, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50301, encodeId=e0e55030109, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=)]
    2015-12-29 樱桃树

    good

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1765451, encodeId=151a1e654512a, content=<a href='/topic/show?id=dee3e139503' target=_blank style='color:#2F92EE;'>#癌症检测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71395, encryptionId=dee3e139503, topicName=癌症检测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Thu Feb 18 01:00:00 CST 2016, time=2016-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50371, encodeId=14ed503e1f9, content=越来越无创,越来越精准化。, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLAibgOibuZnfdFE64hJHibbD6WwEgyaXx7DtibMOSicJ6JZoLEAIdAdkhDmHWO7P7OXg2tkTicZy9libryicw/0, createdBy=aa991670466, createdName=sword20000, createdTime=Wed Dec 30 07:41:00 CST 2015, time=2015-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50346, encodeId=18ac5034640, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Tue Dec 29 21:49:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50334, encodeId=85c2503342f, content=good, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc9a1675161, createdName=樱桃树, createdTime=Tue Dec 29 20:48:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50302, encodeId=50d55030220, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:15:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50299, encodeId=426f502996c, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50300, encodeId=5ecc5030029, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50301, encodeId=e0e55030109, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=)]
    2015-12-29 wzf990214

    值得学习

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1765451, encodeId=151a1e654512a, content=<a href='/topic/show?id=dee3e139503' target=_blank style='color:#2F92EE;'>#癌症检测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71395, encryptionId=dee3e139503, topicName=癌症检测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Thu Feb 18 01:00:00 CST 2016, time=2016-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50371, encodeId=14ed503e1f9, content=越来越无创,越来越精准化。, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLAibgOibuZnfdFE64hJHibbD6WwEgyaXx7DtibMOSicJ6JZoLEAIdAdkhDmHWO7P7OXg2tkTicZy9libryicw/0, createdBy=aa991670466, createdName=sword20000, createdTime=Wed Dec 30 07:41:00 CST 2015, time=2015-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50346, encodeId=18ac5034640, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Tue Dec 29 21:49:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50334, encodeId=85c2503342f, content=good, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc9a1675161, createdName=樱桃树, createdTime=Tue Dec 29 20:48:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50302, encodeId=50d55030220, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:15:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50299, encodeId=426f502996c, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50300, encodeId=5ecc5030029, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50301, encodeId=e0e55030109, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=)]
    2015-12-29 wzf990214

    有意思

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1765451, encodeId=151a1e654512a, content=<a href='/topic/show?id=dee3e139503' target=_blank style='color:#2F92EE;'>#癌症检测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71395, encryptionId=dee3e139503, topicName=癌症检测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Thu Feb 18 01:00:00 CST 2016, time=2016-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50371, encodeId=14ed503e1f9, content=越来越无创,越来越精准化。, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLAibgOibuZnfdFE64hJHibbD6WwEgyaXx7DtibMOSicJ6JZoLEAIdAdkhDmHWO7P7OXg2tkTicZy9libryicw/0, createdBy=aa991670466, createdName=sword20000, createdTime=Wed Dec 30 07:41:00 CST 2015, time=2015-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50346, encodeId=18ac5034640, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Tue Dec 29 21:49:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50334, encodeId=85c2503342f, content=good, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc9a1675161, createdName=樱桃树, createdTime=Tue Dec 29 20:48:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50302, encodeId=50d55030220, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:15:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50299, encodeId=426f502996c, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50300, encodeId=5ecc5030029, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50301, encodeId=e0e55030109, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=)]
    2015-12-29 wzf990214

    不错哦

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1765451, encodeId=151a1e654512a, content=<a href='/topic/show?id=dee3e139503' target=_blank style='color:#2F92EE;'>#癌症检测#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71395, encryptionId=dee3e139503, topicName=癌症检测)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Thu Feb 18 01:00:00 CST 2016, time=2016-02-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50371, encodeId=14ed503e1f9, content=越来越无创,越来越精准化。, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLAibgOibuZnfdFE64hJHibbD6WwEgyaXx7DtibMOSicJ6JZoLEAIdAdkhDmHWO7P7OXg2tkTicZy9libryicw/0, createdBy=aa991670466, createdName=sword20000, createdTime=Wed Dec 30 07:41:00 CST 2015, time=2015-12-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50346, encodeId=18ac5034640, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=101, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=387d1660055, createdName=dhzzm, createdTime=Tue Dec 29 21:49:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50334, encodeId=85c2503342f, content=good, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=fc9a1675161, createdName=樱桃树, createdTime=Tue Dec 29 20:48:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50302, encodeId=50d55030220, content=值得学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=89, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:15:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50299, encodeId=426f502996c, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50300, encodeId=5ecc5030029, content=不错哦, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=50301, encodeId=e0e55030109, content=赞一个, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRiaKicWybj5Q5KN7PWibALciaJ4W5bZwTlDSFRibFu87125pCq0IXePrC0mpbiasADRqL4NcjUoyQCT9De/0, createdBy=7c7e1636498, createdName=wzf990214, createdTime=Tue Dec 29 17:14:00 CST 2015, time=2015-12-29, status=1, ipAttribution=)]
    2015-12-29 wzf990214

    赞一个

    0