J Appl Oral Sci:鼠李糖乳杆菌L8020发酵的牛奶可降低智力障碍患者牙周病的发病风险

2019-08-02 不详 网络

智力障碍(ID)人群一直存在包括牙周病患病率高的问题。使用益生菌治疗牙周病一直是大量研究的焦点,鼠李糖乳杆菌L8020(L8020酸奶)发酵的牛奶可降低四种牙周病原体的口服流行率。这项随机,双盲,安慰剂对照试验旨在比较L8020酸奶(试验组)与安慰剂酸奶(安慰剂组)对23名ID患者的乳头-边缘附着(PMA)指数,牙龈指数( GI)和探诊深度(PD)的影响。所有患者在早餐后需要食用分配的酸奶90天。

智力障碍(ID)人群一直存在包括牙周病患病率高的问题。使用益生菌治疗牙周病一直是大量研究的焦点,鼠李糖乳杆菌L8020(L8020酸奶)发酵的牛奶可降低四种牙周病原体的口服流行率。这项随机,双盲,安慰剂对照试验旨在比较L8020酸奶(试验组)与安慰剂酸奶(安慰剂组)对23名ID患者的乳头-边缘附着(PMA)指数,牙龈指数( GI)和探诊深度(PD)的影响。

所有患者在早餐后需要食用分配的酸奶90天。在酸奶消费开始(基线)之前,消费45天和90天之后以及停止消费之后30天评估PMA指数和GI评分以及PD。学生t检验,Mann-Whitney U检验或Fisher精确检验用于组间比较,重复测量的混合效应模型用于数据分析。

结果显示,PMA指数评分的降低在试验组中显著高于安慰剂组(p <0.001)。在研究期间GI评分也降低,试验组的下降趋势更大。此外,测试组中基线45和90天之间PD的降低倾向于大于安慰剂组。

总之,这些结果表明,定期食用用鼠李糖乳杆菌L8020发酵的牛奶可降低患有ID的个体的牙周病风险。

原始出处:

Yuki O, Furutani C, et al., Effect of bovine milk fermented with Lactobacillus rhamnosus L8020 on periodontal disease in individuals with intellectual disability: a randomized clinical trial. J Appl Oral Sci. 2019 Jul 29;27:e20180564. doi: 10.1590/1678-7757-2018-0564.

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    2021-07-27 ms1000000439112988

    0

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    2020-05-01 小几洁
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  5. [GetPortalCommentsPageByObjectIdResponse(id=1003130, encodeId=97d71003130e2, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35db5557781, createdName=ms1000000439112988, createdTime=Tue Jul 27 21:10:12 CST 2021, time=2021-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2025319, encodeId=407a2025319a9, content=<a href='/topic/show?id=6c8323646a0' target=_blank style='color:#2F92EE;'>#乳杆菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23646, encryptionId=6c8323646a0, topicName=乳杆菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Thu Apr 02 16:52:00 CST 2020, time=2020-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020600, encodeId=9b352020600b3, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Fri May 01 08:52:00 CST 2020, time=2020-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1282307, encodeId=6860128230e73, content=<a href='/topic/show?id=46a06e5220c' target=_blank style='color:#2F92EE;'>#牙周病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67522, encryptionId=46a06e5220c, topicName=牙周病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1376173, createdName=linagood, createdTime=Sun Aug 04 03:52:00 CST 2019, time=2019-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1451172, encodeId=99d614511e253, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Sun Aug 04 03:52:00 CST 2019, time=2019-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530173, encodeId=131715301e32b, content=<a href='/topic/show?id=7e2a6003078' target=_blank style='color:#2F92EE;'>#智力障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60030, encryptionId=7e2a6003078, topicName=智力障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=858e12029830, createdName=mgqwxj, createdTime=Sun Aug 04 03:52:00 CST 2019, time=2019-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370654, encodeId=3efb3e065429, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1bb241978, createdName=phoebeyan520, createdTime=Fri Aug 02 13:03:22 CST 2019, time=2019-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370652, encodeId=d65f3e065223, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Fri Aug 02 12:57:00 CST 2019, time=2019-08-02, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1003130, encodeId=97d71003130e2, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35db5557781, createdName=ms1000000439112988, createdTime=Tue Jul 27 21:10:12 CST 2021, time=2021-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2025319, encodeId=407a2025319a9, content=<a href='/topic/show?id=6c8323646a0' target=_blank style='color:#2F92EE;'>#乳杆菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23646, encryptionId=6c8323646a0, topicName=乳杆菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Thu Apr 02 16:52:00 CST 2020, time=2020-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020600, encodeId=9b352020600b3, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Fri May 01 08:52:00 CST 2020, time=2020-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1282307, encodeId=6860128230e73, content=<a href='/topic/show?id=46a06e5220c' target=_blank style='color:#2F92EE;'>#牙周病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67522, encryptionId=46a06e5220c, topicName=牙周病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1376173, createdName=linagood, createdTime=Sun Aug 04 03:52:00 CST 2019, time=2019-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1451172, encodeId=99d614511e253, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Sun Aug 04 03:52:00 CST 2019, time=2019-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530173, encodeId=131715301e32b, content=<a href='/topic/show?id=7e2a6003078' target=_blank style='color:#2F92EE;'>#智力障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60030, encryptionId=7e2a6003078, topicName=智力障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=858e12029830, createdName=mgqwxj, createdTime=Sun Aug 04 03:52:00 CST 2019, time=2019-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370654, encodeId=3efb3e065429, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1bb241978, createdName=phoebeyan520, createdTime=Fri Aug 02 13:03:22 CST 2019, time=2019-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370652, encodeId=d65f3e065223, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Fri Aug 02 12:57:00 CST 2019, time=2019-08-02, status=1, ipAttribution=)]
  7. [GetPortalCommentsPageByObjectIdResponse(id=1003130, encodeId=97d71003130e2, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35db5557781, createdName=ms1000000439112988, createdTime=Tue Jul 27 21:10:12 CST 2021, time=2021-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2025319, encodeId=407a2025319a9, content=<a href='/topic/show?id=6c8323646a0' target=_blank style='color:#2F92EE;'>#乳杆菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23646, encryptionId=6c8323646a0, topicName=乳杆菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Thu Apr 02 16:52:00 CST 2020, time=2020-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020600, encodeId=9b352020600b3, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Fri May 01 08:52:00 CST 2020, time=2020-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1282307, encodeId=6860128230e73, content=<a href='/topic/show?id=46a06e5220c' target=_blank style='color:#2F92EE;'>#牙周病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67522, encryptionId=46a06e5220c, topicName=牙周病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1376173, createdName=linagood, createdTime=Sun Aug 04 03:52:00 CST 2019, time=2019-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1451172, encodeId=99d614511e253, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Sun Aug 04 03:52:00 CST 2019, time=2019-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530173, encodeId=131715301e32b, content=<a href='/topic/show?id=7e2a6003078' target=_blank style='color:#2F92EE;'>#智力障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60030, encryptionId=7e2a6003078, topicName=智力障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=858e12029830, createdName=mgqwxj, createdTime=Sun Aug 04 03:52:00 CST 2019, time=2019-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370654, encodeId=3efb3e065429, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1bb241978, createdName=phoebeyan520, createdTime=Fri Aug 02 13:03:22 CST 2019, time=2019-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370652, encodeId=d65f3e065223, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Fri Aug 02 12:57:00 CST 2019, time=2019-08-02, status=1, ipAttribution=)]
    2019-08-02 phoebeyan520

    学习了

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1003130, encodeId=97d71003130e2, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=35db5557781, createdName=ms1000000439112988, createdTime=Tue Jul 27 21:10:12 CST 2021, time=2021-07-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2025319, encodeId=407a2025319a9, content=<a href='/topic/show?id=6c8323646a0' target=_blank style='color:#2F92EE;'>#乳杆菌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23646, encryptionId=6c8323646a0, topicName=乳杆菌)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ce68183, createdName=xiongke010, createdTime=Thu Apr 02 16:52:00 CST 2020, time=2020-04-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020600, encodeId=9b352020600b3, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Fri May 01 08:52:00 CST 2020, time=2020-05-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1282307, encodeId=6860128230e73, content=<a href='/topic/show?id=46a06e5220c' target=_blank style='color:#2F92EE;'>#牙周病#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67522, encryptionId=46a06e5220c, topicName=牙周病)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1376173, createdName=linagood, createdTime=Sun Aug 04 03:52:00 CST 2019, time=2019-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1451172, encodeId=99d614511e253, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=医者仁心, createdTime=Sun Aug 04 03:52:00 CST 2019, time=2019-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530173, encodeId=131715301e32b, content=<a href='/topic/show?id=7e2a6003078' target=_blank style='color:#2F92EE;'>#智力障碍#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=60030, encryptionId=7e2a6003078, topicName=智力障碍)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=858e12029830, createdName=mgqwxj, createdTime=Sun Aug 04 03:52:00 CST 2019, time=2019-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370654, encodeId=3efb3e065429, content=学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1bb241978, createdName=phoebeyan520, createdTime=Fri Aug 02 13:03:22 CST 2019, time=2019-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=370652, encodeId=d65f3e065223, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0aa31415219, createdName=orangesking, createdTime=Fri Aug 02 12:57:00 CST 2019, time=2019-08-02, status=1, ipAttribution=)]
    2019-08-02 orangesking

    0