Radiology:活体肾移植供体移植前肾残存皮质体积对移植后肾功能有预测价值

2018-04-23 shaosai MedSci原创

本研究旨在验证是否活体肾移植供体基于CT测量的残存肾皮质能够预测移植后肾功能,并将结果发表在Radiology上。

本研究旨在验证是否活体肾移植供体基于CT测量的残存肾皮质能够预测移植后肾功能,并将结果发表在Radiology上。

本研究共纳入了126例活体肾移植捐献者并在捐献前进行肾脏CT扫描。测量。利用体表面积校正后的剩余肾脏全肾体积和皮质体积。计算全肾体积与BSA比率和肾皮质体积与BSA比率的双变量线性关系。建立2年移植后eGFR、捐献年龄、性别和全肾体积-BSA比率或皮质体积-BSA比率的线性回归模型,以及模型确定系数(R 2)。利用后退法排除无统计学意义的指标,计算简化模型的确定系数。

结果为,皮质体积-BSA比率的相关性要轻微优于全肾-BSA体积(r = 0.48 vs r = 0.44)。纳入所有捐献指标的线性回归模型R 2 为0.66。仅有皮质体积-BSA比率和捐献前eGFR (P = .01和P < .01)是仅有的具有显着性意义的指标。涵盖上述两个变量的最简化模型能够解释全指标模型相同的变异(R 2 = 0.65)。

本研究结果表明,残存肾皮质体积有助于预测2年后捐献后eGFR。因此,皮质-BSA比率可作为评价活体肾功能和指导选择。

原始出处:

Fananapazir G, Benzl R, Corwin MT. et al.Predonation Volume of Future Remnant Cortical Kidney Helps Predict Postdonation Renal Function in Live Kidney Donors.Radiology.DOI: 10.1148/radiol.2018171642

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    2019-02-17 feather85
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    2018-10-08 yese
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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Tue Apr 24 06:25:46 CST 2018, time=2018-04-24, status=1, ipAttribution=)]
  5. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Tue Apr 24 06:56:43 CST 2018, time=2018-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308727, encodeId=7653308e27f1, content=谢谢了.学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Tue Apr 24 06:53:54 CST 2018, time=2018-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308699, encodeId=951f308699c5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Tue Apr 24 06:25:46 CST 2018, time=2018-04-24, status=1, ipAttribution=)]
    2018-04-24 1dd8c52fm63(暂无匿称)

    了解了解.学习学习

    0

  6. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Tue Apr 24 06:56:43 CST 2018, time=2018-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308727, encodeId=7653308e27f1, content=谢谢了.学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Tue Apr 24 06:53:54 CST 2018, time=2018-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308699, encodeId=951f308699c5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Tue Apr 24 06:25:46 CST 2018, time=2018-04-24, status=1, ipAttribution=)]
    2018-04-24 wzb521zf

    一起学习学习

    0

  7. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Tue Apr 24 06:25:46 CST 2018, time=2018-04-24, status=1, ipAttribution=)]
    2018-04-24 1e17414fm02(暂无匿称)

    学习

    0

  8. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Tue Apr 24 06:56:43 CST 2018, time=2018-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308727, encodeId=7653308e27f1, content=谢谢了.学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Tue Apr 24 06:53:54 CST 2018, time=2018-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308699, encodeId=951f308699c5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Tue Apr 24 06:25:46 CST 2018, time=2018-04-24, status=1, ipAttribution=)]
    2018-04-24 执着追梦

    学习.谢谢分享

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1631860, encodeId=10ac1631860db, content=<a href='/topic/show?id=bd782682e3a' target=_blank style='color:#2F92EE;'>#供体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26827, encryptionId=bd782682e3a, topicName=供体)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c9ed21829086, createdName=feather85, createdTime=Sun Feb 17 14:13:00 CST 2019, time=2019-02-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1850669, encodeId=dd831850669ba, content=<a href='/topic/show?id=46c682469e4' target=_blank style='color:#2F92EE;'>#肾功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=82469, encryptionId=46c682469e4, topicName=肾功能)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=28d456, 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyhb9xDeHojCicsdRdyC3XXdGk2ib9yLypZuHN06WeW4HO8WN0GGrgEfvnTX8gsckof05GHOU5OM4Mvx/0, createdBy=9cee1982656, createdName=执着追梦, createdTime=Tue Apr 24 06:56:43 CST 2018, time=2018-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308727, encodeId=7653308e27f1, content=谢谢了.学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=30331616752, createdName=txqjm, createdTime=Tue Apr 24 06:53:54 CST 2018, time=2018-04-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=308699, encodeId=951f308699c5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Tue Apr 24 06:25:46 CST 2018, time=2018-04-24, status=1, ipAttribution=)]
    2018-04-24 txqjm

    谢谢了.学习

    0

  10. 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topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c3da1990174, createdName=yfjms, createdTime=Tue Apr 24 06:25:46 CST 2018, time=2018-04-24, status=1, ipAttribution=)]
    2018-04-24 yfjms

    学习

    0

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