Cell Host Microbe:想从健康饮食中获益?那你得问问肠道菌群答不答应

2017-01-04 sunshine MedSci原创

如果你的新年决心是采取健康饮食,这里需要关注的是肠道微生物的作用。近日,来自圣路易斯华盛顿大学(WUSTL)基因组学和系统生物学中心的一项新研究发现表明,肠道菌群的多样化受典型的西方饮食的影响,该研究结果已发表于Cell Host & Microbe。此外,研究还发现,西方饮食所影响的肠道菌群可能会减弱健康、卡路里较少和植物性饮食的效果。西方饮食(有时被称为“美国标准饮食”)通常被定义为含

如果你的新年决心是采取健康饮食,这里需要关注的是肠道微生物的作用。近日,来自圣路易斯华盛顿大学(WUSTL)基因组学和系统生物学中心的一项新研究发现表明,肠道菌群的多样化受典型的西方饮食的影响,该研究结果已发表于Cell Host & Microbe。

此外,研究还发现,西方饮食所影响的肠道菌群可能会减弱健康、卡路里较少和植物性饮食的效果。

西方饮食(有时被称为“美国标准饮食”)通常被定义为含有少量水果、蔬菜、海鲜、家禽和全谷物,但却含有大量红肉、碳水化合物、饱和脂肪、糖类和加工食品的饮食。

研究已经证实西方饮食是导致肥胖发生的关键因素,会增加心脏病和其他各种疾病的风险。

为了降低这些疾病的风险,植物性饮食(大量蔬菜,水果,全谷类和豆类,少量动物产品)则认为是最好的饮食选择之一。

然而,该项新的研究发现从西方饮食转换为植物性饮食并不能立刻获得想要的效果。

该研究中,研究人员收集了无限制的西方饮食者或者植物性、卡路里较少饮食者的粪便样本。

经过分析,研究者发现植物性饮食者的样本中微生物更具多样性。

接下来,该团队将每种饮食习惯者的肠道微生物群落接种给无菌小鼠(不存在任何微生物的小鼠)。

结果两组小鼠均对新饮食有反应。然而,接种西方饮食习惯者肠道菌群的小鼠比接种植物性饮食者肠道菌群小鼠的反应弱。

然后研究人员将两组小鼠放在同一笼中,两组小鼠均接种了人肠道微生物群:一组是西方饮食习惯者的菌群,另一组是植物性饮食者的菌群。

结果发现植物性饮食者的肠道菌群很快进入西方饮食者的微生物群中;植物性饮食者的肠道微生物显著增加了西方饮食者肠道菌群对植物性饮食的反应。

研究人员希望该研究结果有助于找出可改善人们对健康饮食反应的方法,但是研究人员提醒道,仍需进一步的研究来确定微生物交换背后潜在的机制。

原始出处:

[1]Honor Whiteman. Dieting? Your gut microbes might delay the benefits. MNT, 3 January 2017.

[2]Jeffrey Gordon et al., Prior dietary practices and connections to a human gut microbial metacommunity alter responses to diet interventions, Cell Host & Microbe, 29 December 2016.


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    2017-10-30 维他命
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    2017-04-23 xjy02
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    2017-02-07 wmu姿

    新的研究方向仍需不断探索

    0

  6. 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  7. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLBkyaelI9ia3n9SbuKmBdaY0PqCOzd0nhRUstroXmUmXZ5EBTmibtLEvCCIpyHAqxQXGfZz49ibrwjkg/0, createdBy=39781652829, createdName=雾夜芭蕾, createdTime=Thu Jan 05 07:22:32 CST 2017, time=2017-01-05, status=1, ipAttribution=)]
    2017-01-05 明月清辉

    肠系膜是一个新的器官吗?

    0

  8. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLBkyaelI9ia3n9SbuKmBdaY0PqCOzd0nhRUstroXmUmXZ5EBTmibtLEvCCIpyHAqxQXGfZz49ibrwjkg/0, createdBy=39781652829, createdName=雾夜芭蕾, createdTime=Thu Jan 05 07:22:32 CST 2017, time=2017-01-05, status=1, ipAttribution=)]
    2017-01-05 komasun

    学习起来了

    0

  9. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLBkyaelI9ia3n9SbuKmBdaY0PqCOzd0nhRUstroXmUmXZ5EBTmibtLEvCCIpyHAqxQXGfZz49ibrwjkg/0, createdBy=39781652829, createdName=雾夜芭蕾, createdTime=Thu Jan 05 07:22:32 CST 2017, time=2017-01-05, status=1, ipAttribution=)]
    2017-01-05 雾夜芭蕾

    健康饮食习惯因人而异

    0

  10. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/ajNVdqHZLLBkyaelI9ia3n9SbuKmBdaY0PqCOzd0nhRUstroXmUmXZ5EBTmibtLEvCCIpyHAqxQXGfZz49ibrwjkg/0, createdBy=39781652829, createdName=雾夜芭蕾, createdTime=Thu Jan 05 07:22:32 CST 2017, time=2017-01-05, status=1, ipAttribution=)]
    2017-01-05 雾夜芭蕾

    中西方饮食习惯差异很大

    0