Pediatrics:补充DHA对早产儿过敏和呼吸转归的影响

2011-06-30 刘玉华 医学论坛网

 澳大利亚一项多中心随机对照研究发现,给小于33孕周的早产儿补充二十二碳六烯酸(DHA)可减少男婴和所有出生体重低于1250克婴儿的支气管肺发育不良(BPD)发生率及男婴的花粉症。该研究于6月27日在线发表于《儿科学》(Pediatrics)杂志。   已知,DHA与炎症反应下调相关。该研究旨在报告,补充DHA对早产儿长期过敏和呼吸系统转归的影响。   研究人员对喝了母乳的早产儿(少于33孕周

 澳大利亚一项多中心随机对照研究发现,给小于33孕周的早产儿补充二十二碳六烯酸(DHA)可减少男婴和所有出生体重低于1250克婴儿的支气管肺发育不良(BPD)发生率及男婴的花粉症。该研究于6月27日在线发表于《儿科学》(Pediatrics)杂志。

  已知,DHA与炎症反应下调相关。该研究旨在报告,补充DHA对早产儿长期过敏和呼吸系统转归的影响。

  研究人员对喝了母乳的早产儿(少于33孕周)的转归进行了比较,其母亲服用金枪鱼油(高DHA饮食)或大豆油(标准-DHA)胶囊。收集的数据包括:BPD和双亲所报告的出生18个月的过敏情况。他们登记了657名婴儿(高DHA饮食组:322名;标准DHA组:335名),其中,93.5%的婴儿完成了18个月的随访。

  研究人员发现,在男婴和所有出生体重低于1250克的婴儿中BPD均减少,相对危险(RR)分别为0.67(P=0.03)和 0.75(P=0.04)。而且呼吸支持持续时间,住院时间,或家庭氧疗的需求均未受影响。高DHA饮食组和所有男婴中,12个月或18个月时报告的花粉症均下降,RR分别为0.41(P=0.03)和0.15; P=0.01)。早产儿中补充DHA对婴儿哮喘、湿疹或食物过敏无影响。

  相关链接:High-Dose Docosahexaenoic Acid Supplementation of Preterm Infants: Respiratory and Allergy Outcomes

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    2015-09-27 mance

    For the love of God, keep writing these arcleits.

    0

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    2011-09-19 feather89
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    2011-07-16 hbwxf
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