帕金森患者在被移植4万个猪脑细胞后,病情居然出现了好转

2017-06-13 新华社 新华社

新华社北京6月13日电新西兰一家生物技术公司宣布,他们通过将猪脑细胞移植到患者脑部治疗帕金森病的试验初见成效,此前接受移植的4名患者病情有改善,并在移植后18个月内一直保持效果。据英国《新科学家》杂志最近报道,位于新西兰奥克兰市的“活细胞技术公司”上个月又完成了对18名帕金森病患者的移植手术试验,并设置了对照组,试验结果预计今年11月揭晓。帕金森病是一种中枢神经系统退化疾病,患者脑部分泌多巴胺的神

新华社北京6月13日电新西兰一家生物技术公司宣布,他们通过将猪脑细胞移植到患者脑部治疗帕金森病的试验初见成效,此前接受移植的4名患者病情有改善,并在移植后18个月内一直保持效果。

据英国《新科学家》杂志最近报道,位于新西兰奥克兰市的“活细胞技术公司”上个月又完成了对18名帕金森病患者的移植手术试验,并设置了对照组,试验结果预计今年11月揭晓。

帕金森病是一种中枢神经系统退化疾病,患者脑部分泌多巴胺的神经细胞死亡,导致肢体震颤、行动困难等。现行疗法是补充多巴胺,但效果会逐渐减退。

“活细胞技术公司”利用的是位于猪脑室脉络丛的一类中枢神经细胞,它含有几种生长因子,以及对维持神经细胞健康至关重要的信号分子。

研究人员设计出一种多孔微型“胶囊”,每个可容纳1000个猪脑细胞。这种胶囊使猪脑细胞分泌的生长因子能渗透到周围的患者脑组织里,同时保护猪脑细胞不受患者免疫细胞攻击。

在初次试验中,研究人员为每名患者的一侧大脑植入了40个胶囊。结果发现,在199分制的帕金森病严重程度评估体系中,4名患者的病情平均好转了14分,而通常情况下如不加干预病情会日益恶化。不过目前还不能完全排除安慰剂效应。

新近接受移植的18名患者大脑两侧都被植入胶囊,数量最多达到120个,研究人员希望进一步验证该疗法的效果。

猪的解剖结构和生理特性与人相近,并且容易饲养,是目前异种器官和细胞移植的主要研究对象。移植猪胰岛细胞治疗糖尿病的疗法已经在一些国家获批。

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    2017-07-31 Coco5816

    有意思

    0

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    2017-06-15 muzishouyi
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    2017-06-15 坚强007

    赞赞赞

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1765010, encodeId=f2061e6501003, content=<a href='/topic/show?id=df00e086653' target=_blank style='color:#2F92EE;'>#病情#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=22, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=70866, encryptionId=df00e086653, topicName=病情)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=778d36, createdName=柳叶一刀, createdTime=Mon Feb 19 16:43:00 CST 2018, time=2018-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=228531, encodeId=d599228531f4, content=有意思, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJECOI3z1sgUHAkZmaibc3WatVTwLeT5sK7gFumIunAwEwb5jdSIcr9mFjL0PjUW8emoKChia20o0Qg/132, createdBy=a4ef2100982, createdName=Coco5816, createdTime=Mon Jul 31 18:20:25 CST 2017, time=2017-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1424903, encodeId=5e2e1424903ec, content=<a href='/topic/show?id=bbd084993fd' target=_blank style='color:#2F92EE;'>#脑细胞#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=84993, encryptionId=bbd084993fd, topicName=脑细胞)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=39a23929286, createdName=bettycmoon, createdTime=Thu Jun 15 14:43:00 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1555251, encodeId=e6c91555251b7, content=<a href='/topic/show?id=f367681e434' target=_blank style='color:#2F92EE;'>#猪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=68174, encryptionId=f367681e434, topicName=猪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9ec214601917, createdName=muzishouyi, createdTime=Thu Jun 15 14:43:00 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=211035, encodeId=cd4f21103504, content=赞赞赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=e5171668917, createdName=坚强007, createdTime=Thu Jun 15 08:21:17 CST 2017, time=2017-06-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=210637, encodeId=db3b21063ea2, content=还需要更长期的观察,动物细胞移植的人体能不能提的功能还需要观察。当然,对于帕金森氏患者而言,只要他能分泌多巴其实就是有效地, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c4a5105539, createdName=lovetcm, createdTime=Wed Jun 14 12:01:57 CST 2017, time=2017-06-14, status=1, ipAttribution=)]
    2017-06-14 lovetcm

    还需要更长期的观察,动物细胞移植的人体能不能提的功能还需要观察。当然,对于帕金森氏患者而言,只要他能分泌多巴其实就是有效地

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