JACC:肠球菌心内膜炎的当代临床研究

2020-02-19 不详 MedSci原创

肠球菌心内膜炎(EE)在西方国家中逐渐增多,然而却缺乏大型临床研究数据。本研究的目的旨在描述GAMES临床研究中的EE临床特征及其预后因素。本研究纳入分析了516例EE患者和3308例非肠球菌心内膜炎(NEE)患者作为对照。分析结果显示,EE患者年龄更大、慢性肺疾病更多、慢性心衰更多,更易有心内膜炎史和退行性瓣膜疾病。EE患者更常伴有主动脉瓣假体,急性心衰发生风险更高,但起搏器和除颤仪器植入的概率

肠球菌心内膜炎(EE)在西方国家中逐渐增多,然而却缺乏大型临床研究数据。本研究的目的旨在描述GAMES临床研究中的EE临床特征及其预后因素。

本研究纳入分析了516例EE患者和3308例非肠球菌心内膜炎(NEE)患者作为对照。分析结果显示,EE患者年龄更大、慢性肺疾病更多、慢性心衰更多,更易有心内膜炎史和退行性瓣膜疾病。EE患者更常伴有主动脉瓣假体,急性心衰发生风险更高,但起搏器和除颤仪器植入的概率更低。心脏手术在EE患者中更少见(40.7% vs. 45.9%; p = 0.024)。两组患者的住院率和一年死亡率无明显差异,但EE患者的复发率更高。另外,急性心衰、脓毒性休克和瓣旁并发症是死亡率增加的危险因素,而心内膜炎史是保护因素。

研究结果显示,肠球菌心内膜炎在假体瓣膜中更常见,而在起搏器/除颤仪器的植入中更少见,且复发率高于非肠球菌心内膜炎。

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    2020-12-08 hbwxf
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    2020-02-23 14737642m56(暂无昵称)

    东方国家有类似研究么?

    0

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