Nat Commun:黄酮类摄入量与较低的死亡率相关

2019-08-17 海北 MedSci原创

已有的研究显示,类黄酮,植物来源的多酚化合物,与健康益处有关。然而,现今为止,观察性研究的证据不完整。

已有的研究显示,类黄酮,植物来源的多酚化合物,与健康益处有关。然而,现今为止,观察性研究的证据不完整:关于癌症死亡率的研究很少,生活方式风险因素对早期死亡率的调节作用尚不清楚。

在最近的一项前瞻性队列研究中,丹麦饮食,癌症和健康队列与丹麦全国登记处的56,048名参与者被包含进来,其被随访了23年,期间共有14,083人死亡。

适度的习惯性黄酮类摄入量与全因,心血管和癌症相关的死亡率呈负相关。这种强烈的关联稳定在摄入量约500毫克/天。

此外,吸烟者中总黄酮摄入量与死亡率结果之间的负相关关系比非吸烟者更强,更线性,以及重度(> 20 g / d)酒精摄入者比低中度(<20 g / d)关联更强。

这些研究结果强调了通过增加富含类黄酮的食物摄入量来降低死亡率的潜力,特别是在吸烟者和高度酗酒者中。


原始出处:

Nicola P. Bondonno et al. Flavonoid intake is associated with lower mortality in the Danish Diet Cancer and Health Cohort. Nature Communications, 2019; 10 (1) DOI: 10.1038/s41467-019-11622-x


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    2021-09-22 lancyteng

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    2019-12-03 liuli5079
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    2020-05-06 liye789132251
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    2020-01-10 fengyi821
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    2020-07-16 lmm397

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